Mikrobiom und neurodegenerative Erkrankungen
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Bauerl C, Collado MC, Diaz Cuevas A et al (2018) Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimer’s disease during lifespan. Lett Appl Microbiol 66:464–471
Berer K, Mues M, Koutrolos M et al (2011) Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479:538–541
Calvo-Barreiro L, Eixarch H, Montalban X et al (2018) Combined therapies to treat complex diseases: The role of the gut microbiota in multiple sclerosis. Autoimmun Rev 17:165–174
Cani PD, Bibiloni R, Knauf C et al (2008) Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57:1470–1481
Cattaneo A, Cattane N, Galluzzi S et al (2017) Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. Neurobiol Aging 49:60–68
Erny D, Hrabe de Angelis AL, Jaitin D et al (2015) Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci 18:965–977
Forsyth CB, Shannon KM, Kordower JH et al (2011) Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson’s disease. PLoS ONE 6:e28032
Haghikia A, Jorg S, Duscha A et al (2015) Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine. Immunity 43:817–829
Harach T, Marungruang N, Duthilleul N et al (2017) Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota. Sci Rep 7:41802
Hufnagel DA, Tukel C, Chapman MR (2013) Disease to dirt: The biology of microbial amyloids. PLoS Pathog 9:e1003740
Keshavarzian A, Green SJ, Engen PA et al (2015) Colonic bacterial composition in Parkinson’s disease. Mov Disord 30:1351–1360
Minter MR, Zhang C, Leone V et al (2016) Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease. Sci Rep 6:30028
Postuma RB, Gagnon JF, Pelletier A et al (2013) Prodromal autonomic symptoms and signs in Parkinson’s disease and dementia with Lewy bodies. Mov Disord 28:597–604
Rao SSC, Rehman A, Yu S et al (2018) Brain fogginess, gas and bloating: A link between SIBO, probiotics and metabolic acidosis. Clin Transl Gastroenterol 9:162
Sampson TR, Debelius JW, Thron T et al (2016) Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease. Cell 167:1469–1480.e12
Sender R, Fuchs S, Milo R (2016) Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 164:337–340
Shahi SK, Freedman SN, Mangalam AK (2017) Gut microbiome in multiple sclerosis: The players involved and the roles they play. Gut Microbes 8:607–615
Shen L, Liu L, Ji HF (2017) Alzheimer’s disease histological and behavioral manifestations in transgenic mice correlate with specific gut microbiome state. J Alzheimers Dis 56:385–390
Socias SB, Gonzalez-Lizarraga F, Avila CL et al (2018) Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases. Prog Neurobiol 162:17–36
Stanley D, Mason LJ, Mackin KE et al (2016) Translocation and dissemination of commensal bacteria in post-stroke infection. Nat Med 22:1277–1284
Tankou SK, Regev K, Healy BC et al (2018) A probiotic modulates the microbiome and immunity in multiple sclerosis. Ann Neurol 83:1147–1161
Tomas-Camardiel M, Rite I, Herrera AJ et al (2004) Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system. Neurobiol Dis 16:190–201
Ulusoy A, Phillips RJ, Helwig M et al (2017) Brain-to-stomach transfer of alpha-synuclein via vagal preganglionic projections. Acta Neuropathol 133:381–393
Villumsen M, Aznar S, Pakkenberg B et al (2019) Inflammatory bowel disease increases the risk of Parkinson’s disease: A Danish nationwide cohort study 1977–2014. Gut 68:18–24
Wilson QN, Wells M, Davis AT et al (2018) Greater microbial translocation and vulnerability to metabolic disease in healthy aged female monkeys. Sci Rep 8:11373
Xu R, Wang Q (2016) Towards understanding brain-gut-microbiome connections in Alzheimer’s disease. BMC Syst Biol 10(Suppl 3):63
Yin J, Liao SX, He Y et al (2015) Dysbiosis of gut microbiota with reduced trimethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient Ischemic attack. J Am Heart Assoc. https://doi.org/10.1161/JAHA.115.002699
Zaura E, Brandt BW, Teixeira de Mattos MJ et al (2015) Same exposure but two radically different responses to antibiotics: Resilience of the salivary microbiome versus long-term microbial shifts in feces. mBio. https://doi.org/10.1128/mBio.01693-15