Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming

Immunity - Tập 25 Số 1 - Trang 153-162 - 2006
Rhys S. Allan1, Jason Waithman1, Sammy Bedoui2, Claerwen M. Jones1, José A. Villadangos2, Yifan Zhan2, Andrew M. Lew2, Ken Shortman2, William R. Heath2, Federico Carbone1
1The Department of Microbiology and Immunology, The University of Melbourne, Parkville 3010, Victoria, Australia
2Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3050, Victoria, Australia

Tóm tắt

Từ khóa


Tài liệu tham khảo

Albert, 1998, Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs, Nature, 392, 86, 10.1038/32183

Allan, 2003, Epidermal viral immunity induced by CD8α+ dendritic cells but not by Langerhans cells, Science, 301, 1925, 10.1126/science.1087576

Angeli, 2001, Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection, J. Exp. Med., 193, 1135, 10.1084/jem.193.10.1135

Bacci, 1997, High and low doses of haptens dictate whether dermal or epidermal antigen-presenting cells promote contact hypersensitivity, Eur. J. Immunol., 27, 442, 10.1002/eji.1830270214

Banchereau, 1998, Dendritic cells and the control of immunity, Nature, 392, 245, 10.1038/32588

Belz, 2002, The CD8α+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens, J. Exp. Med., 196, 1099, 10.1084/jem.20020861

Belz, 2004, Cutting edge: conventional CD8α+ dendritic cells are generally involved in priming CTL immunity to viruses, J. Immunol., 172, 1996, 10.4049/jimmunol.172.4.1996

Belz, 2004, Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus, Proc. Natl. Acad. Sci. USA, 101, 8670, 10.1073/pnas.0402644101

Bennett, 1998, Help for cytotoxic-T-cell responses is mediated by CD40 signalling, Nature, 393, 478, 10.1038/30996

Bosnjak, 2005, Herpes simplex virus infection of human dendritic cells induces apoptosis and allows cross-presentation via uninfected dendritic cells, J. Immunol., 174, 2220, 10.4049/jimmunol.174.4.2220

De Smedt, 1996, Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo, J. Exp. Med., 184, 1413, 10.1084/jem.184.4.1413

den Haan, 2000, CD8+ but not CD8− dendritic cells cross-prime cytotoxic T cells in vivo, J. Exp. Med., 192, 1685, 10.1084/jem.192.12.1685

Fleeton, 2004, Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice, J. Exp. Med., 200, 235, 10.1084/jem.20041132

Garg, 2003, Genetic tagging shows increased frequency and longevity of antigen-presenting, skin-derived dendritic cells in vivo, Nat. Immunol., 4, 907, 10.1038/ni962

Henri, 2001, The dendritic cell populations of mouse lymph nodes, J. Immunol., 167, 741, 10.4049/jimmunol.167.2.741

Inaba, 1998, Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells, J. Exp. Med., 188, 2163, 10.1084/jem.188.11.2163

Itano, 2003, Antigen presentation to naive CD4 T cells in the lymph node, Nat. Immunol., 4, 733, 10.1038/ni957

Jennings, 1991, CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice, Cell. Immunol., 133, 234, 10.1016/0008-8749(91)90194-G

Jones, 2003, Herpes simplex virus type 2 induces rapid cell death and functional impairment of murine dendritic cells in vitro, J. Virol., 77, 11139, 10.1128/JVI.77.20.11139-11149.2003

Kamath, 2002, Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs, Blood, 100, 1734, 10.1182/blood.V100.5.1734.h81702001734_1734_1741

Katz, 1979, Epidermal Langerhans cells are derived from cells originating in bone marrow, Nature, 282, 324, 10.1038/282324a0

Kissenpfennig, 2005, Dynamics and function of Langerhans cells in vivo dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells, Immunity, 22, 643, 10.1016/j.immuni.2005.04.004

Kleindienst, 2003, Endogenous dendritic cells are required for amplification of T cell responses induced by dendritic cell vaccines in vivo, J. Immunol., 170, 2817, 10.4049/jimmunol.170.6.2817

Lindquist, 2004, Visualizing dendritic cell networks in vivo, Nat. Immunol., 5, 1243, 10.1038/ni1139

Lyons, 1994, Determination of lymphocyte division by flow cytometry, J. Immunol. Methods, 171, 131, 10.1016/0022-1759(94)90236-4

Macatonia, 1987, Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies, J. Exp. Med., 166, 1654, 10.1084/jem.166.6.1654

Merad, 2002, Langerhans cells renew in the skin throughout life under steady-state conditions, Nat. Immunol., 3, 1135, 10.1038/ni852

Mikloska, 2001, Immature monocyte-derived dendritic cells are productively infected with herpes simplex virus type 1, J. Virol., 75, 5958, 10.1128/JVI.75.13.5958-5964.2001

Mueller, 2002, Characterization of two TCR transgenic mouse lines specific for herpes simplex virus, Immunol. Cell Biol., 80, 156, 10.1046/j.1440-1711.2002.01071.x

Mueller, 2002, Rapid cytotoxic T lymphocyte activation occurs in the draining lymph nodes after cutaneous herpes simplex virus infection as a result of early antigen presentation and not the presence of virus, J. Exp. Med., 195, 651, 10.1084/jem.20012023

Norbury, 2002, Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo, Nat. Immunol., 3, 265, 10.1038/ni762

Orr, 2005, Inhibition of MHC class I is a virulence factor in herpes simplex virus infection of mice, PLoS Pathog, 1, e7, 10.1371/journal.ppat.0010007

Pulendran, 1997, Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice, J. Immunol., 159, 2222, 10.4049/jimmunol.159.5.2222

Reis e Sousa, 1993, Phagocytosis of antigens by Langerhans cells in vitro, J. Exp. Med., 178, 509, 10.1084/jem.178.2.509

Ridge, 1998, A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell, Nature, 393, 474, 10.1038/30989

Romani, 1989, Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells, J. Exp. Med., 169, 1169, 10.1084/jem.169.3.1169

Salio, 1999, Inhibition of dendritic cell maturation by herpes simplex virus, Eur. J. Immunol., 29, 3245, 10.1002/(SICI)1521-4141(199910)29:10<3245::AID-IMMU3245>3.0.CO;2-X

Salomon, 1998, Three populations of mouse lymph node dendritic cells with different origins and dynamics, J. Immunol., 160, 708, 10.4049/jimmunol.160.2.708

Sato, 2004, Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartments, Proc. Natl. Acad. Sci. USA, 101, 16274, 10.1073/pnas.0406268101

Scheinecker, 2002, Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node, J. Exp. Med., 196, 1079, 10.1084/jem.20020991

Schoenberger, 1998, T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions, Nature, 393, 480, 10.1038/31002

Schuler, 1985, Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro, J. Exp. Med., 161, 526, 10.1084/jem.161.3.526

Smith, 2003, Cutting edge: conventional CD8α+ dendritic cells are preferentially involved in CTL priming after footpad infection with herpes simplex virus-1, J. Immunol., 170, 4437, 10.4049/jimmunol.170.9.4437

Smith, 2004, Cognate CD4+ T cell licensing of dendritic cells in CD8+ T cell immunity, Nat. Immunol., 5, 1143, 10.1038/ni1129

Sporri, 2005, Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function, Nat. Immunol., 6, 163, 10.1038/ni1162

Steinman, 2002, Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance, Proc. Natl. Acad. Sci. USA, 99, 351, 10.1073/pnas.231606698

Stock, 2004, Cutting edge: prolonged antigen presentation after herpes simplex virus-1 skin infection, J. Immunol., 173, 2241, 10.4049/jimmunol.173.4.2241

Thery, 2002, Exosomes: composition, biogenesis and function, Nat. Rev. Immunol., 2, 569, 10.1038/nri855

Turley, 2003, Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model, J. Exp. Med., 198, 1527, 10.1084/jem.20030966

van Lint, 2004, Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation, J. Immunol., 172, 392, 10.4049/jimmunol.172.1.392

Villadangos, 2005, Life cycle, migration and antigen presenting functions of spleen and lymph node dendritic cells: Limitations of the Langerhans cells paradigm, Semin. Immunol., 17, 262, 10.1016/j.smim.2005.05.015

Wilson, 2006, Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity, Nat. Immunol., 7, 165, 10.1038/ni1300

Zhao, 2003, Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2, J. Exp. Med., 197, 153, 10.1084/jem.20021109