Migration of Endothelial Progenitor Cells Mediated by Stromal Cell-Derived Factor-1α/CXCR4 via PI3K/Akt/eNOS Signal Transduction Pathway

Journal of Cardiovascular Pharmacology - Tập 50 Số 3 - Trang 274-280 - 2007
Hao Zheng1, Guosheng Fu1, Tao Dai1, He Huang1
1the Department of Cardiovascular Diseases, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, PR China.

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Nagasawa, 1994, Molecular cloning and structure of a pre-B-cell growth-stimulating factor., Proc Natl Acad Sci USA, 91, 2305, 10.1073/pnas.91.6.2305

Bleul, 1996, The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry., Nature, 382, 829, 10.1038/382829a0

Asahara, 1997, Isolation of putative progenitor endothelial cells for angiogenesis., Science, 275, 964, 10.1126/science.275.5302.964

Shi, 1998, Evidence for circulating bone marrow-derived endothelial cells., Blood, 92, 362, 10.1182/blood.V92.2.362

Verma, 2002, Fundamentals of endothelial function for the clinical cardiologist., Circulation, 105, 546, 10.1161/hc0502.104540

Hill, 2003, Circulating endothelial progenitor cells, vascular function, and cardiovascular risk., N Engl J Med, 348, 593, 10.1056/NEJMoa022287

Vasa, 2001, Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease., Circ Res, 89, E1, 10.1161/hh1301.093953

Yamaguchi, 2003, Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization., Circulation, 107, 1322, 10.1161/01.CIR.0000055313.77510.22

Segal, 2006, Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes., Diabetes, 55, 102, 10.2337/diabetes.55.01.06.db05-0803

Veit, 2004, Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells., Cancer Res, 64, 5291, 10.1158/0008-5472.CAN-04-1112

Wang, 2000, Stromal cell-derived factor-1a stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progrnitor cells: role of phosphoinositol-3 kinase and protein kinase C., Blood, 95, 2505, 10.1182/blood.V95.8.2505

Cheresh, 1999, Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells., J Cell Biol, 146, 1107, 10.1083/jcb.146.5.1107

Floridi, 2003, Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells., J Neuroimmunol, 135, 38, 10.1016/S0165-5728(02)00432-0

Lataillade, 2000, Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival., Blood, 95, 756, 10.1182/blood.V95.3.756

Kalka, 2000, Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization., Proc Natl Acad Sci USA, 97, 3422, 10.1073/pnas.97.7.3422

Dimmeler, 2000, Phosphorylation of endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration., FEBS Lett, 477, 258, 10.1016/S0014-5793(00)01657-4

Kahn, 2004, Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation., Blood, 103, 2942, 10.1182/blood-2003-07-2607

Burns, 2006, A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development., J Exp Med, 203, 2201, 10.1084/jem.20052144

Askari, 2006, Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet. 2003;362:697-703., J Exp Med, 203, 2201

Chang, 2001, Mammalian MAP kinase signalling cascades., Nature, 410, 37, 10.1038/35065000

Johnson, 2002, Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases., Science, 298, 1911, 10.1126/science.1072682

Ganju, 1998, The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways., J Biol Chem, 273, 23169, 10.1074/jbc.273.36.23169

Guinamard, 1999, B cell antigen receptor engagement inhibits stromal cell-derived factor (SDF)-1alpha chemotaxis and promotes protein kinase C (PKC)-induced internalization of CXCR4., J Exp Med, 189, 1461, 10.1084/jem.189.9.1461

Sotsios, 1999, The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes., J Immunol, 163, 5954, 10.4049/jimmunol.163.11.5954

Barbero, 2003, Stromal cell-derived factor 1a stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt., Cancer Res, 63, 1969

Dimmeler, 2001, HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway., J Clin Invest, 108, 391, 10.1172/JCI200113152

Bahlmann, 2003, Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin., Kidney Int, 64, 1648, 10.1046/j.1523-1755.2003.00279.x

Ackah, 2005, Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis., J Clin Invest, 115, 2119, 10.1172/JCI24726

Imanishi, 2005, Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity., J Hypertens, 23, 1699, 10.1097/01.hjh.0000176788.12376.20