Microfluidics device for drug discovery, screening and delivery

Neff, 2011, Peak oil, food systems, and public health, Am J Public Health, 101, 1587, 10.2105/AJPH.2011.300123 Schwartz, 2011, Public health and medicine in an age of energy scarcity: the case of petroleum, Am J Public Health, 101, 1560, 10.2105/AJPH.2010.205187 Dias, 2012, A historical overview of natural products in drug discovery, Metabolites, 2, 303, 10.3390/metabo2020303 Mohs, 2017, Drug discovery and development: role of basic biological research, Alzheimers Dement, 3, 651, 10.1016/j.trci.2017.10.005 Helleboid, 2014, The identification of naturally occurring neoruscogenin as a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1), J Biomol Screen, 19, 399, 10.1177/1087057113497095 Dincer, 2019, Disposable sensors in diagnostics, food, and environmental monitoring, Adv Mater, 31, 10.1002/adma.201806739 Neuži, 2012, Revisiting lab-on-a-chip technology for drug discovery, Nat Rev Drug Discov, 11, 620, 10.1038/nrd3799 Sun, 2019, Recent advances in microfluidics for drug screening, Biomicrofluidics, 13, 10.1063/1.5121200 Chou, 2015, Recent advances in applications of droplet microfluidics, Micromachines, 6, 1249, 10.3390/mi6091249 Suea-Ngam, 2019, Droplet microfluidics: From proof-of-concept to real-world utility?, Chem Commun, 55, 9895, 10.1039/C9CC04750F Damiati, 2018, Microfluidic devices for drug delivery systems and drug screening, Genes (Basel), 9, 103, 10.3390/genes9020103 Kitazoe, 2012, Fabrication of functionalized double-lamellar multifunctional envelope-type nanodevices using a microfluidic chip with a chaotic mixer array, PLoS One, 7, 10.1371/journal.pone.0039057 Riahi, 2015, Microfluidics for advanced drug delivery systems, Curr Opin Chem Eng, 7, 101, 10.1016/j.coche.2014.12.001 Vladisavljević, 2013, Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery, Adv Drug Deliv Rev, 65, 1626, 10.1016/j.addr.2013.07.017 Pang, 2004, High-throughput multiplexed capillary electrophoresis in drug discovery, Drug Discov Today, 9, 1072, 10.1016/S1359-6446(04)03293-3 Dittrich, 2006, Lab-on-a-chip: microfluidics in drug discovery, Nat Rev Drug Discov, 5, 210, 10.1038/nrd1985 Tsui, 2013, Microfluidics-assisted in vitro drug screening and carrier production, Adv Drug Deliv Rev, 65, 1575, 10.1016/j.addr.2013.07.004 Kuramoto, 2008, On-chip fabrication of mutifunctional envelope-type nanodevices for gene delivery, Anal Bioanal Chem, 391, 2729, 10.1007/s00216-008-2124-7 Koh, 2009, Delivery of polyethylenimine/DNA complexes assembled in a microfluidics device, Mol Pharm, 6, 1333, 10.1021/mp900016q Sant, 2012, Microfabrication technologies for oral drug delivery, Adv Drug Deliv Rev, 64, 496, 10.1016/j.addr.2011.11.013 Ghosh, 2020, Gastrointestinal-resident, shape-changing microdevices extend drug release in vivo, Sci Adv, 6, 4133, 10.1126/sciadv.abb4133 Hood, 2014, Microfluidic remote loading for rapid single-step liposomal drug preparation, Lab Chip, 14, 3359, 10.1039/C4LC00390J Huang, 2017, Microfluidic hydrodynamic focusing synthesis of polymer-lipid nanoparticles for siRNA delivery, Oncotarget, 8, 96826, 10.18632/oncotarget.18281 Jung, 2020, Polymeric nanoparticles controlled by on-chip self-assembly enhance cancer treatment effectiveness, Adv Healthc Mater, 9, 10.1002/adhm.202001633 Guo, 2012, Droplet microfluidics for high-throughput biological assays, Lab Chip, 12, 2146, 10.1039/c2lc21147e Teh, 2008, Droplet microfluidics, Lab Chip, 8, 198, 10.1039/b715524g Pirbodaghi, 2015, Investigating the fluid dynamics of rapid processes within microfluidic devices using bright-field microscopy, Lab Chip, 15, 2140, 10.1039/C5LC00175G Jiang, 2017, Droplet-based light-sheet fluorescence microscopy for high-throughput sample preparation, 3-D imaging and quantitative analysis on a chip, Lab Chip, 17, 2193, 10.1039/C7LC00164A Barnes, 2006, Raman spectroscopic monitoring of droplet polymerization in a microfluidic device, Analyst, 131, 1027, 10.1039/b603693g Kim, 2017, Raman spectroscopy compatible PDMS droplet microfluidic culture and analysis platform towards on-chip lipidomics, Analyst, 142, 1054, 10.1039/C6AN02221A Zhu, 2013, Analytical detection techniques for droplet microfluidics—a review, Anal Chim Acta, 787, 24, 10.1016/j.aca.2013.04.064 Pekin, 2011, Quantitative and sensitive detection of rare mutations using droplet-based microfluidics, Lab Chip, 11, 2156, 10.1039/c1lc20128j Lyu, 2015, Quantitative detection of cells expressing BlaC using droplet-based microfluidics for use in the diagnosis of tuberculosis, Biomicrofluidics, 9, 10.1063/1.4928879 Benz, 2013, Protein-protein interaction analysis in single microfluidic droplets using FRET and fluorescence lifetime detection, Lab Chip, 13, 2808, 10.1039/c3lc00057e Chen, 2015, A novel droplet dosing strategy-based versatile microscale biosensor for detection of DNA, protein and ion, Sensors Actuators B Chem, 215, 206, 10.1016/j.snb.2015.03.065 Rane, 2012, Droplet microfluidics for amplification-free genetic detection of single cells, Lab Chip, 12, 3341, 10.1039/c2lc40537g Huebner, 2007, Quantitative detection of protein expression in single cells using droplet microfluidics, Chem Commun, 1218, 10.1039/b618570c Srisa-Art, 2009, Analysis of protein–protein interactions by using droplet-based microfluidics, Chembiochem, 10, 1605, 10.1002/cbic.200800841 Brouzes, 2009, Droplet microfluidic technology for single-cell high-throughput screening, Proc Natl Acad Sci, 106, 14195, 10.1073/pnas.0903542106 Wong, 2017, Drug screening of cancer cell lines and human primary tumors using droplet microfluidics, Sci Rep, 7, 9109, 10.1038/s41598-017-08831-z Beneyton, 2016, High-throughput screening of filamentous fungi using nanoliter-range droplet-based microfluidics, Sci Rep, 6, 10.1038/srep27223 de Carvalho, 2021, Hybrid microgels produced via droplet microfluidics for sustainable delivery of hydrophobic and hydrophilic model nanocarriers, Mater Sci Eng C, 118, 10.1016/j.msec.2020.111467 Fang, 2021, Digital droplet infusion, Lab Chip, 21, 502, 10.1039/D0LC00896F