Microfluidic in-vitro fertilization technologies: Transforming the future of human reproduction

Agarwal, 2015, A unique view on male infertility around the globe, Reprod. Biol. Endocrinol. : RBE (Rev. Bras. Entomol.), 13, 37, 10.1186/s12958-015-0032-1 Eskew, 2017, A history of developments to improve in vitro fertilization, Mo. Med., 114, 156 Meseguer, 2012, Full in vitro fertilization laboratory mechanization: toward robotic assisted reproduction?, Fertil. Steril., 97, 1277, 10.1016/j.fertnstert.2012.03.013 Kushnir, 2022, The future of IVF: the new normal in human reproduction, Reprod. Sci., 29, 849, 10.1007/s43032-021-00829-3 Choucair, 2021, The value of the modern embryologist to a successful IVF system: revisiting an age-old question, Middle East Fertil. Soc. J., 26, 15, 10.1186/s43043-021-00061-8 Katz, 2011, Costs of infertility treatment: results from an 18-month prospective cohort study, Fertil. Steril., 95, 915, 10.1016/j.fertnstert.2010.11.026 Veiga, 2022, Recalculating the staff required to run a modern assisted reproductive technology laboratory, Hum. Reprod., 37, 1774, 10.1093/humrep/deac121 Ashrafi, 2013, ICSI outcome in infertile couples with different causes of infertility: a cross-sectional study, Int J Fertil Steril, 7, 88 Kovacs, 2014, Embryo selection: the role of time-lapse monitoring, Reprod. Biol. Endocrinol. : RBE (Rev. Bras. Entomol.), 12, 124, 10.1186/1477-7827-12-124 Whitesides, 2006, The origins and the future of microfluidics, Nature, 442, 368, 10.1038/nature05058 Ma, 2011, In vitro fertilization on a single-oocyte positioning system integrated with motile sperm selection and early embryo development, Anal. Chem., 83, 2964, 10.1021/ac103063g Sackmann, 2014, The present and future role of microfluidics in biomedical research, Nature, 507, 181, 10.1038/nature13118 Weng, 2019, IVF-on-a-Chip: recent advances in microfluidics technology for in vitro fertilization, SLAS Technol., 24, 373, 10.1177/2472630319851765 Hull, 1985, Population study of causes, treatment, and outcome of infertility, Br. Med. J., 291, 1693, 10.1136/bmj.291.6510.1693 Henkel, 2003, Sperm preparation for ART, Reprod. Biol. Endocrinol. : RBE (Rev. Bras. Entomol.), 1, 108, 10.1186/1477-7827-1-108 Chen, 2011, Analysis of sperm concentration and motility in a microfluidic device, Microfluid. Nanofluidics, 10, 59, 10.1007/s10404-010-0646-8 Chinnasamy, 2018, Guidance and self-sorting of active swimmers: 3D periodic arrays increase persistence length of human sperm selecting for the fittest, Adv. Sci., 5 Tasoglu, 2013, Exhaustion of racing sperm in nature-mimicking microfluidic channels during sorting, Small, 9, 3374, 10.1002/smll.201300020 Zhang, 2011, Lensless imaging for simultaneous microfluidic sperm monitoring and sorting, Lab Chip, 11, 2535, 10.1039/c1lc20236g Seo, 2007, Development of sorting, aligning, and orienting motile sperm using microfluidic device operated by hydrostatic pressure, Microfluid. Nanofluidics, 3, 561, 10.1007/s10404-006-0142-3 Wu, 2017, High-throughput flowing upstream sperm sorting in a retarding flow field for human semen analysis, Analyst, 142, 938, 10.1039/C6AN02420C Zaferani, 2018, Rheotaxis-based separation of sperm with progressive motility using a microfluidic corral system, Proc. Natl. Acad. Sci. USA, 115, 8272, 10.1073/pnas.1800819115 Kaupp, 2008, Mechanisms of sperm chemotaxis, Annu. Rev. Physiol., 70, 93, 10.1146/annurev.physiol.70.113006.100654 Oren-Benaroya, 2008, The sperm chemoattractant secreted from human cumulus cells is progesterone, Hum. Reprod., 23, 2339, 10.1093/humrep/den265 Anderson, 1995, Atrial natriuretic peptide: a chemoattractant of human spermatozoa by a guanylate cyclase-dependent pathway, Mol. Reprod. Dev., 40, 371, 10.1002/mrd.1080400314 Xie, 2010, Integration of sperm motility and chemotaxis screening with a microchannel-based device, Clinic. Chem., 56, 1270, 10.1373/clinchem.2010.146902 Li, 2018, Novel distance-progesterone-combined selection approach improves human sperm quality, J. Transl. Med., 16, 203, 10.1186/s12967-018-1575-7 Gatica, 2013, Picomolar gradients of progesterone select functional human sperm even in subfertile samples, Mol. Hum. Reprod., 19, 559, 10.1093/molehr/gat037 Bahat, 2003, Thermotaxis of mammalian sperm cells: a potential navigation mechanism in the female genital tract, Nat. Med., 9, 149, 10.1038/nm0203-149 Bahat, 2012, Thermotaxis of human sperm cells in extraordinarily shallow temperature gradients over a wide range, PLoS One, 7, 10.1371/journal.pone.0041915 Boryshpolets, 2015, Behavioral mechanism of human sperm in thermotaxis: a role for hyperactivation, Hum. Reprod., 30, 884, 10.1093/humrep/dev002 Perez-Cerezales, 2018, Sperm selection by thermotaxis improves ICSI outcome in mice, Sci. Rep., 8, 2902, 10.1038/s41598-018-21335-8 Ko, 2018, Design, fabrication, and testing of a microfluidic device for thermotaxis and chemotaxis assays of sperm, SLAS Technol., 23, 507, 10.1177/2472630318783948 Li, 2014, The construction of an interfacial valve-based microfluidic chip for thermotaxis evaluation of human sperm, Biomicrofluidics, 8, 10.1063/1.4866851 Kime, 2001, Computer-assisted sperm analysis (CASA) as a tool for monitoring sperm quality in fish, Comp. Biochem. Physiol. C Toxicol. Pharmacol., 130, 425, 10.1016/S1532-0456(01)00270-8 Franken, 2012, Semen analysis and sperm function testing, Asian J. Androl., 14, 6, 10.1038/aja.2011.58 Vasan, 2011, Semen analysis and sperm function tests: how much to test?, Indian J. Urol, 27, 41, 10.4103/0970-1591.78424 Perez-Cerezales, 2012, Comparison of four methods to evaluate sperm DNA integrity between mouse caput and cauda epididymidis, Asian J. Androl., 14, 335, 10.1038/aja.2011.119 Bungum, 2007, Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome, Hum. Reprod., 22, 174, 10.1093/humrep/del326 Chen, 2013, Sperm quality assessment via separation and sedimentation in a microfluidic device, Analyst, 138, 4967, 10.1039/c3an00900a Segerink, 2010, On-chip determination of spermatozoa concentration using electrical impedance measurements, Lab Chip, 10, 1018, 10.1039/b923970g Chen, 2013, Direct characterization of motion-dependent parameters of sperm in a microfluidic device: proof of principle, Clinic. Chem., 59, 493, 10.1373/clinchem.2012.190686 Elsayed, 2015, Development of computer-assisted sperm analysis plugin for analyzing sperm motion in microfluidic environments using Image-J, Theriogenology, 84, 1367, 10.1016/j.theriogenology.2015.07.021 Kanakasabapathy, 2017, An automated smartphone-based diagnostic assay for point-of-care semen analysis, Sci. Transl. Med., 9, 10.1126/scitranslmed.aai7863 Yang, 2017, Paper-based microfluidic devices: emerging themes and applications, Anal. Chem., 89, 71, 10.1021/acs.analchem.6b04581 Martinez, 2010, Diagnostics for the developing world: microfluidic paper-based analytical devices, Anal. Chem., 82, 3, 10.1021/ac9013989 Matsuura, 2014, Paper-based diagnostic devices for evaluating the quality of human sperm, Microfluid. Nanofluidics, 16, 857, 10.1007/s10404-014-1378-y Matsuura, 2017, Relationship between porcine sperm motility and sperm enzymatic activity using paper-based devices, Sci. Rep., 7, 10.1038/srep46213 Nosrati, 2016, Paper-based quantification of male fertility potential, Clinic. Chem., 62, 458, 10.1373/clinchem.2015.250282 Rienzi, 2012, The oocyte, Hum. Reprod., 27, i2, 10.1093/humrep/des200 Smith, 2017, Application of microfluidic technologies to human assisted reproduction, Mol. Hum. Reprod., 23, 257 Van de Velde, 1997, Effects of different hyaluronidase concentrations and mechanical procedures for cumulus cell removal on the outcome of intracytoplasmic sperm injection, Hum. Reprod., 12, 2246, 10.1093/humrep/12.10.2246 Zeringue, 2004, Microfluidic removal of cumulus cells from Mammalian zygotes, Methods Mol. Biol., 254, 365 Zeringue, 2005, Early mammalian embryo development depends on cumulus removal technique, Lab Chip, 5, 86, 10.1039/b316494m Iwasaki, 2018, Simple separation of good quality bovine oocytes using a microfluidic device, Sci. Rep., 8, 10.1038/s41598-018-32687-6 Luo, 2015, Deformation of a single mouse oocyte in a constricted microfluidic channel, Microfluid. Nanofluidics, 19, 883, 10.1007/s10404-015-1614-0 Weng, 2018, On-chip oocyte denudation from cumulus-oocyte complexes for assisted reproductive therapy, Lab Chip, 18, 3892, 10.1039/C8LC01075G Mokhtare, 2022, Non-contact ultrasound oocyte denudation, Lab Chip, 22, 777, 10.1039/D1LC00715G Xia, 2013, Biology of polyspermy in IVF and its clinical indication, Curr. Obstetrics Gynecol. Rep., 2, 226, 10.1007/s13669-013-0059-2 Clark, 2005, Reduction of polyspermic penetration using biomimetic microfluidic technology during in vitro fertilization, Lab Chip, 5, 1229, 10.1039/b504397m Suh, 2006, IVF within microfluidic channels requires lower total numbers and lower concentrations of sperm, Hum. Reprod., 21, 477, 10.1093/humrep/dei323 Lopez-Garcia, 2008, Sperm motion in a microfluidic fertilization device, Biomed. Microdevices, 10, 709, 10.1007/s10544-008-9182-7 Han, 2010, Integration of single oocyte trapping, in vitro fertilization and embryo culture in a microwell-structured microfluidic device, Lab Chip, 10, 2848, 10.1039/c005296e Angione, 2015, Simple perfusion apparatus for manipulation, tracking, and study of oocytes and embryos, Fertil. Steril., 103, 281, 10.1016/j.fertnstert.2014.09.039 Heo, 2012, Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation, Lab Chip, 12, 2240, 10.1039/c2lc21050a Kim, 2009, A microfluidic in vitro cultivation system for mechanical stimulation of bovine embryos, Electrophoresis, 30, 3276, 10.1002/elps.200900157 Wong, 2014, Cryopreservation of human embryos and its contribution to in vitro fertilization success rates, Fertil. Steril., 102, 19, 10.1016/j.fertnstert.2014.05.027 Brown, 1996, Natural cycle in-vitro fertilization with embryo cryopreservation prior to chemotherapy for carcinoma of the breast, Hum. Reprod., 11, 197, 10.1093/oxfordjournals.humrep.a019017 Mazur, 1970, Cryobiology: the freezing of biological systems, Science, 168, 939, 10.1126/science.168.3934.939 Rall, 1985, Ice-free cryopreservation of mouse embryos at -196 degrees C by vitrification, Nature, 313, 573, 10.1038/313573a0 Weng, 2019, Exploring dynamics and structure of biomolecules, cryoprotectants, and water using molecular dynamics simulations: implications for biostabilization and biopreservation, Annu. Rev. Biomed. Eng., 21, 1, 10.1146/annurev-bioeng-060418-052130 Zhao, 2017, A microfluidic perfusion approach for on-chip characterization of the transport properties of human oocytes, Lab Chip, 17, 1297, 10.1039/C6LC01532H Heo, 2011, Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform, Lab Chip, 11, 3530, 10.1039/c1lc20377k Lai, 2015, Slow and steady cell shrinkage reduces osmotic stress in bovine and murine oocyte and zygote vitrification, Hum. Reprod., 30, 37, 10.1093/humrep/deu284 Tirgar, 2021, Toward embryo cryopreservation-on-a-chip: a standalone microfluidic platform for gradual loading of cryoprotectants to minimize cryoinjuries, Biomicrofluidics, 15, 10.1063/5.0047185 Pyne, 2014, Digital microfluidic processing of mammalian embryos for vitrification, PLoS One, 9, 10.1371/journal.pone.0108128 Zheng, 2018, On-chip loading and unloading of cryoprotectants facilitate cell cryopreservation by rapid freezing, Sensor. Actuator. B Chem., 255, 647, 10.1016/j.snb.2017.08.084 Bhattacharjee, 2016, The upcoming 3D-printing revolution in microfluidics, Lab Chip, 16, 1720, 10.1039/C6LC00163G Nielsen, 2020, 3D printed microfluidics, Annu. Rev. Anal. Chem., 13, 45, 10.1146/annurev-anchem-091619-102649 Wu, 2020, Organ-on-a-chip: recent breakthroughs and future prospects, Biomed. Eng. Online, 19, 9, 10.1186/s12938-020-0752-0 Yu, 2019 Ren, 2014, New materials for microfluidics in biology, Curr. Opin. Biotechnol., 25, 78, 10.1016/j.copbio.2013.09.004 Berlanda, 2021, Recent advances in microfluidic technology for bioanalysis and diagnostics, Anal. Chem., 93, 311, 10.1021/acs.analchem.0c04366