Microemulsions in Systems with Lecithin and Oleic Acid for Medical Use
Tóm tắt
Reverse microemulsions for use in medicine and cosmetics in systems containing lecithin (a mixture of phospholipids with a lecithin content of ~22 wt %), oleic acid, vaseline oil, vegetable oil, essential oil (in an amount of less than 5 wt %), and water are developed. The hydrodynamic diameter of the droplets of the microemulsions ranges from 15 to 80 nm. The microemulsions are stable when heated up to 45°C: the mass loss is less than 1%, and no phase transitions and chemical reactions accompanied by the absorption or release of heat are observed. The microemulsions possess a delayed release of water-soluble substances: 3.6% water-soluble dye Rhodamine C is released from the microemulsion in 7 h of dialysis.
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