Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions – A case study with itraconazole

European Journal of Pharmaceutics and Biopharmaceutics - Tập 70 - Trang 590-596 - 2008
Van Eerdenbrugh Bernard1, Vercruysse Sofie1, Martens Johan A2, Vermant Jan3, Froyen Ludo4, Van Humbeeck Jan4, Van den Mooter Guy1, Augustijns Patrick1
1Laboratory for Pharmacotechnology and Biopharmacy, Leuven, Belgium
2Center for Surface Chemistry and Catalysis, Heverlee, Belgium
3Department of Chemical Engineering, Heverlee, Belgium
4Metallurgy and Materials Engineering Department, Heverlee, Belgium

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European Journal of Pharmaceutics and Biopharmaceutics

Tập 70

590-596

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