MicroRNAs regulating cell pluripotency and vascular differentiation

Vascular Pharmacology - Tập 55 - Trang 69-78 - 2011
Lynsey Howard1, Nicole M. Kane1, Graeme Milligan2, Andrew H. Baker1
1BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK
2Institute of Neuroscience & Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ, UK

Tài liệu tham khảo

Becker, 2007, Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells, Journal of Cellular Physiology, 210, 517, 10.1002/jcp.20903 Benetti, 2008, A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases, Nat. Struct. Mol. Biol., 15, 268, 10.1038/nsmb.1399 Boettger, 2009, Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster, The Journal of Clinical Investigation, 119, 2634, 10.1172/JCI38864 Bonauer, 2009, MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice, Science, 324, 1710, 10.1126/science.1174381 Brons, 2007, Derivation of pluripotent epiblast stem cells from mammalian embryos, Nature, 448, 191, 10.1038/nature05950 Caporali, 2011, Deregulation of microRNA-503 Contributes to Diabetes Mellitus -Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia / Clinical Perspective, Circulation, 123, 282, 10.1161/CIRCULATIONAHA.110.952325 Carmeliet, 2011, Molecular mechanisms and clinical applications of angiogenesis, Nature, 473, 298, 10.1038/nature10144 Chang, 2009, Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation, Proceedings of the National Academy of Sciences, 106, 3384, 10.1073/pnas.0808300106 Chen, 2008, Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5, Blood, 111, 1217, 10.1182/blood-2007-07-104133 Chen, 2006, The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation, Nature Genetics, 38, 228, 10.1038/ng1725 Chen, 2008, Integration of external signaling pathways with the core transcriptional network in embryonic stem cells, Cell, 133, 1106, 10.1016/j.cell.2008.04.043 Condorelli, 2010, MicroRNAs in heart disease: putative novel therapeutic targets?, European Heart Journal, 31, 649, 10.1093/eurheartj/ehp573 Cordes, 2009, miR-145 and miR-143 regulate smooth muscle cell fate and plasticity, Nature, 460, 705, 10.1038/nature08195 Davis, 2009, Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype, Journal of Biological Chemistry, 284, 3728, 10.1074/jbc.M808788200 Denli, 2004, Processing of primary microRNAs by the microprocessor complex, Nature, 432, 231, 10.1038/nature03049 Dews, 2006, Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster, Nature Genetics, 38, 1060, 10.1038/ng1855 Doebele, 2010, Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells, Blood, 115, 4944, 10.1182/blood-2010-01-264812 Elia, 2009, The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease, Cell Death and Differentiation, 16, 1590, 10.1038/cdd.2009.153 Fasanaro, 2008, MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand ephrin-A3, Journal of Biological Chemistry, 283, 15878, 10.1074/jbc.M800731200 Feldman, 2006, G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis, Nat. Cell. Biol., 8, 188, 10.1038/ncb1353 Fish, 2008, miR-126 regulates angiogenic signaling and vascular integrity, Developmental Cell, 15, 272, 10.1016/j.devcel.2008.07.008 Giraldez, 2005, MicroRNAs regulate brain morphogenesis in zebrafish, Science, 308, 833, 10.1126/science.1109020 Greer Card, 2008, Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells, Molecular and Cellular Biology, 28, 6426, 10.1128/MCB.00359-08 Gregory, 2004, The microprocessor complex mediates the genesis of microRNAs, Nature, 432, 235, 10.1038/nature03120 Guo, 2010, Mammalian microRNAs predominantly act to decrease target mRNA levels, Nature, 466, 835, 10.1038/nature09267 Harris, 2008, MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1, Proceedings of the National Academy of Sciences, 105, 1516, 10.1073/pnas.0707493105 Heng, 2010, Transcriptional regulation in embryonic stem cells, vol. 695, 76 Hosoda, 2011, Human Cardiac Stem Cell Differentiation Is Regulated by a Mircrine Mechanism / Clinical Perspective, Circulation, 123, 1287, 10.1161/CIRCULATIONAHA.110.982918 Houbaviy, 2003, Embryonic stem cell-specific microRNAs, Developmental Cell, 5, 351, 10.1016/S1534-5807(03)00227-2 Huang, 2010, miR-10a contributes to retinoid acid-induced smooth muscle cell differentiation, Journal of Biological Chemistry, 285, 9383, 10.1074/jbc.M109.095612 Huntzinger, 2011, Gene silencing by microRNAs: contributions of translational repression and mRNA decay, Nature Reviews Genetics, 12, 99, 10.1038/nrg2936 Hurst, 2009, Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis, Cancer Research, 69, 1279, 10.1158/0008-5472.CAN-08-3559 Ivey, 2008, MicroRNA regulation of cell lineages in mouse and human embryonic stem cells, Cell Stem Cell, 2, 219, 10.1016/j.stem.2008.01.016 Judson, 2009, Embryonic stem cell-specific microRNAs promote induced pluripotency, Nat. Biotech., 27, 459, 10.1038/nbt.1535 Kane, 2010, Derivation of endothelial cells from human embryonic stem cells by directed differentiation: analysis of microRNA and angiogenesis in vitro and in vivo, Arteriosclerosis, Thrombosis, and Vascular Biology, 30, 1389, 10.1161/ATVBAHA.110.204800 Kanellopoulou, 2005, Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing, Genes & Development, 19, 489, 10.1101/gad.1248505 Kashyap, 2009, Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the nanog, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs, Stem Cells and Development, 18, 1093, 10.1089/scd.2009.0113 Kazenwadel, 2010, Prox1 expression is negatively regulated by miR-181 in endothelial cells, Blood, 116, 2395, 10.1182/blood-2009-12-256297 Kim, 2009, A study of microRNAs in silico and in vivo: emerging regulators of embryonic stem cells, FEBS Journal, 276, 2140, 10.1111/j.1742-4658.2009.06932.x Knight, 2001, A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans, Science, 293, 2269, 10.1126/science.1062039 Kuhn, 2010, MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype, American Journal of Respiratory Cell and Molecular Biology, 42, 506, 10.1165/rcmb.2009-0123OC Kwon, 2005, MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling, Proceedings of the National Academy of Sciences of the United States of America, 102, 18986, 10.1073/pnas.0509535102 Laflamme, 2011, Heart regeneration, Nature, 473, 326, 10.1038/nature10147 Lai, 2011, Advancements in reprogramming strategies for the generation of induced pluripotent stem cells, Journal of Assisted Reproduction and Genetics, 1 Lakshmipathy, 2007, MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells, Stem Cells and Development, 16, 1003, 10.1089/scd.2007.0026 Landgraf, 2007, A mammalian microRNA expression atlas based on small RNA library sequencing, Cell, 129, 1401, 10.1016/j.cell.2007.04.040 Larsson, 2009, Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1, Genome Medicine, 1, 108, 10.1186/gm108 Laurent, 2008, Comprehensive MicroRNA Profiling Reveals a Unique Human Embryonic Stem Cell Signature Dominated by a Single Seed Sequence, Stem Cells, 26, 1506, 10.1634/stemcells.2007-1081 Lee, 2003, The nuclear RNase III Drosha initiates microRNA processing, Nature, 425, 415, 10.1038/nature01957 Lee, 2007, MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression, Proceedings of the National Academy of Sciences, 104, 20350, 10.1073/pnas.0706901104 Lin, 2009, Myc-regulated microRNAs attenuate embryonic stem cell differentiation, EMBO Journal, 28, 3157, 10.1038/emboj.2009.254 Lin, 2011, Regulation of somatic cell reprogramming through inducible mir-302 expression, Nucleic Acids Research, 39, 1054, 10.1093/nar/gkq850 Liu, 2008, microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart, Genes & Development, 22, 3242, 10.1101/gad.1738708 Lund, 2004, Nuclear export of microRNA precursors, Science, 303, 95, 10.1126/science.1090599 Marson, 2008, Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells, Cell, 134, 521, 10.1016/j.cell.2008.07.020 Matsa, 2011, Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation, European Heart Journal, 32, 952, 10.1093/eurheartj/ehr073 Melton, 2010, MicroRNA regulation of embryonic stem cell self-renewal and differentiation, Advances in Experimental Medicine and Biology, 695, 105, 10.1007/978-1-4419-7037-4_8 Mendell, 2008, miRiad Roles for the miR-17–92 Cluster in Development and Disease, Cell, 133, 217, 10.1016/j.cell.2008.04.001 Nakatake, 2006, Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells, Molecular and Cellular Biology, 26, 7772, 10.1128/MCB.00468-06 Nicoli, 2010, MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis, Nature, 464, 1196, 10.1038/nature08889 O'Donnell, 2005, c-Myc-regulated microRNAs modulate E2F1 expression, Nature, 435, 839, 10.1038/nature03677 Ohtsuka, 2008, Molecular and biological properties of pluripotent embryonic stem cells, Gene Therapy, 15, 74, 10.1038/sj.gt.3303065 Pan, 2011, Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality, Biochemical and Biophysical Research Communications, 408, 369, 10.1016/j.bbrc.2011.02.119 Qi, 2009, MicroRNAs regulate human embryonic stem cell division, Cell Cycle, 8, 3729, 10.4161/cc.8.22.10033 Qiu, 2010, Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells, Nucleic Acids Research, 38, 1240, 10.1093/nar/gkp1071 Rao, 2006, Myogenic factors that regulate expression of muscle-specific microRNAs, Proceedings of the National Academy of Sciences, 103, 8721, 10.1073/pnas.0602831103 Reddy, 2008, Bone marrow subsets differentiate into endothelial cells and pericytes contributing to ewing's tumor vessels, Molecular Cancer Research, 6, 929, 10.1158/1541-7786.MCR-07-2189 Rybak, 2008, A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment, Nature Cell Biology, 10, 987, 10.1038/ncb1759 Sengupta, 2009, MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells, Stem Cells, 27, 1524, 10.1002/stem.84 Sinkkonen, 2008, MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells, Nature Structural and Molecular Biology, 15, 259, 10.1038/nsmb.1391 Sluijter, 2010, MicroRNA-1 and -499 regulate differentiation and proliferation in human-derived cardiomyocyte progenitor cells, Arteriosclerosis, Thrombosis, and Vascular Biology, 30, 859, 10.1161/ATVBAHA.109.197434 Smale, 2010, Pioneer factors in embryonic stem cells and differentiation, Current Opinion in Genetics & Development, 20, 519, 10.1016/j.gde.2010.06.010 Small, 2011, Pervasive roles of microRNAs in cardiovascular biology, Nature, 469, 336, 10.1038/nature09783 Smith, 2010, Myc represses primitive endoderm differentiation in pluripotent stem cells, Cell Stem Cell, 7, 343, 10.1016/j.stem.2010.06.023 Stadler, 2010, Characterization of microRNAs involved in embryonic stem cell states, Stem Cells and Development, 19, 935, 10.1089/scd.2009.0426 Suarez, 2007, Dicer dependent MicroRNAs regulate gene expression and functions in human endothelial cells, Circulation Research, 100, 1164, 10.1161/01.RES.0000265065.26744.17 Suárez, 2008, Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis, Proceedings of the National Academy of Sciences, 105, 14082, 10.1073/pnas.0804597105 Suh, 2004, Human embryonic stem cells express a unique set of microRNAs, Developmental Biology, 270, 488, 10.1016/j.ydbio.2004.02.019 Taguchi, 2008, Identification of hypoxia-inducible factor-1α as a novel target for miR-17-92 microrna cluster, Cancer Research, 68, 5540, 10.1158/0008-5472.CAN-07-6460 Takaya, 2009, MicroRNA-1 and microRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells, Circulation Journal, 73, 1492, 10.1253/circj.CJ-08-1032 Tay, 2008, MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation, Nature, 455, 1124, 10.1038/nature07299 van Rooij, 2007, MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets, The Journal of Clinical Investigation, 117, 2369, 10.1172/JCI33099 Ventura, 2008, Targeted deletion reveals essential and overlapping functions of the miR-17 92 family of miRNA clusters, Cell, 132, 875, 10.1016/j.cell.2008.02.019 Viswanathan, 2008, Selective blockade of microRNA processing by Lin28, Science, 320, 97, 10.1126/science.1154040 Wakioka, 2001, Spred is a sprouty-related suppressor of Ras signalling, Nature, 412, 647, 10.1038/35088082 Wang, 2007, DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal, Nature Genetics, 39, 380, 10.1038/ng1969 Wang, 2008, The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis, Developmental Cell, 15, 261, 10.1016/j.devcel.2008.07.002 Wang, 2008, Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation, Nature Genetics, 40, 1478, 10.1038/ng.250 Weber, 2006, A limited set of human microRNA is deregulated in follicular thyroid carcinoma, Journal of Clinical Endocrinology and Metabolism, 91, 3584, 10.1210/jc.2006-0693 Wellner, 2009, The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs, Nature Cell Biology, 11, 1487, 10.1038/ncb1998 Wilson, 2009, MicroRNA profiling of human-induced pluripotent stem cells, Stem Cells and Development, 18, 749, 10.1089/scd.2008.0247 Wilson, 2010, Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells/clinical perspective, Circulation. Cardiovascular Genetics, 3, 426, 10.1161/CIRCGENETICS.109.934281 Würdinger, 2008, miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells, Cancer Cell, 14, 382, 10.1016/j.ccr.2008.10.005 Xie, 2011, MicroRNA-1 regulates smooth muscle cell differentiation by repressing kruppel-like factor 4, Stem Cells and Development, 20, 205, 10.1089/scd.2010.0283 Xin, 2009, MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury, Genes & Development, 23, 2166, 10.1101/gad.1842409 Yang, 2005, Dicer is required for embryonic angiogenesis during mouse development, Journal of Biological Chemistry, 280, 9330, 10.1074/jbc.M413394200 Zhang, 2011, A human iPSC model of hutchinson gilford progeria reveals vascular smooth muscle and mesenchymal stem cell defects, Cell Stem Cell, 8, 31, 10.1016/j.stem.2010.12.002 Zhao, 2007, Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2, Cell, 129, 303, 10.1016/j.cell.2007.03.030 Zhao, 2011, Immunogenicity of induced pluripotent stem cells, Nature, 474, 212, 10.1038/nature10135 Zhou, 2011, Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23∼27∼24 clusters, Proceedings of the National Academy of Sciences, 108, 8287, 10.1073/pnas.1105254108