MicroRNA circolanti come biomarcatori per il diabete mellito di tipo 2: avanzamenti e prospettive future

Springer Science and Business Media LLC - Tập 23 - Trang 447-453 - 2022
Giuseppina Emanuela Grieco1,2, Daniela Fignani1,2, Francesco Dotta1,2,3, Guido Sebastiani1,2
1Unità di Ricerca Diabetologica, Dipartimento di Scienze Mediche Chirurgiche e Neuroscienze, Università di Siena, Siena, Italia
2Fondazione Umberto Di Mario, Siena, Italia
3Centro Regionale Toscano per la Medicina di Precisione (CReMeP), Siena, Italia

Tóm tắt

Il diabete mellito di tipo 2 (DMT2) è una malattia metabolica cronica eterogenea in costante aumento. In questa rassegna, al fine di identificare un gruppo di microRNA (miRNA) con potenziale applicazione in clinica come biomarcatori per la diagnosi, prognosi e selezione di terapie personalizzate per i pazienti con DMT2, abbiamo effettuato una ricerca sistematica di letteratura, identificando e selezionando 10 miRNA (miR-126-3p, miR-223-3p, miR-21-5p, miR-15a-5p, miR-24-3p, miR-34a-5p, miR-146a-5p, miR-148a-3p, miR-30d-5p e miR-30c-5p).

Tài liệu tham khảo

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