MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met

International Journal of Oncology - Tập 42 Số 3 - Trang 957-962 - 2013
Liguang Wang1, Ni Yang1, Benhua Su2, Xueru Mu3, Hongchang Shen3, Jiajun Du1
1Department of thoracic surgery, Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan, P.R. China
2Department of Medical Engineering, Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan, P.R. China
3Institute for Cancer Research, Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan, P.R. China

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Lee, 1993, The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14, Cell, 75, 843, 10.1016/0092-8674(93)90529-Y

Lee, 2003, The nuclear RNase III Drosha initiates microRNA processing, Nature, 425, 415, 10.1038/nature01957

Kong, 2009, Strategies for profiling microRNA expression, J Cell Physiol, 218, 22, 10.1002/jcp.21577

Hutvágner, 2001, A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA, Science, 293, 834, 10.1126/science.1062961

Grishok, 2001, Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing, Cell, 106, 23, 10.1016/S0092-8674(01)00431-7

Schwarz, 2003, Asymmetry in the assembly of the RNAi enzyme complex, Cell, 115, 199, 10.1016/S0092-8674(03)00759-1

Ørom, 2008, MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation, Mol Cell, 30, 460, 10.1016/j.molcel.2008.05.001

Brennecke, 2005, Principles of microRNA-target recognition, PLoS Biol, 3, E85, 10.1371/journal.pbio.0030085

Bartel, 2004, MicroRNAs genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5

Calin, 2004, Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers, Proc Natl Acad Sci USA, 101, 2999, 10.1073/pnas.0307323101

Crawford, 2008, MicroRNA-126 inhibits invasion in nonsmall cell lung carcinoma cell lines, Biochem Biophys Res Commun, 373, 607, 10.1016/j.bbrc.2008.06.090

Zhu, 2008, MicroRNA-21 targets tumor suppressor genes in invasion and metastasis, Cell Res, 18, 350, 10.1038/cr.2008.24

Tavazoie, 2008, Endogenous human microRNAs that suppress breast cancer metastasis, Nature, 451, 147, 10.1038/nature06487

Nicoloso, 2009, MicroRNAs - the micro steering wheel of tumour metastases, Nat Rev Cancer, 9, 293, 10.1038/nrc2619

Valastyan, 2009, A pleiotropically acting microRNA miR-31, inhibits breast cancer metastasis, Cell, 137, 1032, 10.1016/j.cell.2009.03.047

Kong, 2008, MicroRNA-155 is regulated by the transforming growth factor beta/ Smad pathway and contributes to epithelial cell plasticity by targeting RhoA, Mol Cell Biol, 28, 6773, 10.1128/MCB.00941-08

Asangani, 2008, MicroRNA-21 (miR-21) posttranscriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer, Oncogene, 27, 2128, 10.1038/sj.onc.1210856

Gabriely, 2008, MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators, Mol Cell Biol, 28, 5369, 10.1128/MCB.00479-08

Yang, 2006, Exploring a new twist on tumor metastasis, Cancer Res, 66, 4549, 10.1158/0008-5472.CAN-05-3850

Lodygin, 2008, Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer, Cell Cycle, 7, 2591, 10.4161/cc.7.16.6533

Bommer, 2007, p53-mediated activation of miRNA34 candidate tumor-suppressor genes, Curr Biol, 17, 1298, 10.1016/j.cub.2007.06.068

Zhang, 2007, microRNAs as oncogenes and tumor suppressors, Dev Biol, 302, 1, 10.1016/j.ydbio.2006.08.028

He, 2007, A microRNA component of the p53 tumour suppressor network, Nature, 447, 1130, 10.1038/nature05939

Tarasov, 2007, Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest, Cell Cycle, 6, 1586, 10.4161/cc.6.13.4436

Cohen, 2006, Denoising feedback loops by thresholding-a new role for microRNAs, Genes Dev, 20, 2769, 10.1101/gad.1484606

Naran, 2009, Inhibition of HGF/MET as therapy for malignancy, Expert Opin Ther Targets, 13, 569, 10.1517/14728220902853917

Furlan, 2011, Abl interconnects oncogenic Met and p53 core pathways in cancer cells, Cell Death Differ, 18, 1608, 10.1038/cdd.2011.23