MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart

Virginija Jazbutyte1, Jan Fiedler1, Susanne Kneitz2, Paolo Galuppo3, Annette Just1, Angelika Holzmann1, Johann Bauersachs3, Thomas Thum4
1Institute of Molecular and Translational Therapeutic Strategies (IMTTS), IFB-Tx, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
2Microarray Core Facility, Interdisciplinary Centre of Clinical Research, University of Würzburg, Würzburg, Germany
3Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany
4Centre for Clinical and Basic Research, IRCCS San Raffaele, Rome, Italy

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