MicroRNA-216a inhibits neuronal apoptosis in a cellular Parkinson’s disease model by targeting Bax

Xiaobo Yang1, Meng Zhang2, Meng Wang3, Anqi Wang3, Yongning Deng3, Hongmei Cao2
1Department of Psychology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China.
2Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China
3Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 Yanta Western Road, Xi'an, Shaanxi, 710061, People's Republic of China.

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Akh A, Filatova EV, Karabanov AV et al (2015) miRNA expression is highly sensitive to a drug therapy in Parkinson's disease. Parkinsonism Relat Disord 21(1):72–74

Armstrong RA (2017) Visual dysfunction in Parkinson's disease. Int Rev Neurobiol 134(6):921–946

Bai X, Tang Y, Yu M, Wu L, Wang J (2017) Downregulation of blood serum microRNA 29 family in patients with Parkinson’s disease. Sci Rep 7(1):5411

Cai X, Jia H, Liu Z et al (2010) Polyhydroxylated fullerene derivative C60(OH)24 prevents mitochondrial dysfunction and oxidative damage in an MPP+-induced cellular model of Parkinson's disease. J Neurosci Res 86(16):3622–3634

Caneda-Ferrón B, Girolamo LAD, Costa T, Beck KE, Layfield R, Billett EE (2010) Assessment of the direct and indirect effects of MPP+ and dopamine on the human proteasome: implications for Parkinson’s disease aetiology. J Neurochem 105(1):225–238

Casas S, García S, Cabrera R, Nanfaro F, Escudero C, Yunes R (2011) Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats. Pharmacol Biochem Behav 99(4):614–618

Chang D, Nalls MA, Hallgrímsdóttir IB, Hunkapiller J, van der Brug M, Cai F, International Parkinson's Disease Genomics Consortium, 23andMe Research Team, Kerchner GA, Ayalon G, Bingol B, Sheng M, Hinds D, Behrens TW, Singleton AB, Bhangale TR, Graham RR (2017) A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. Nat Genet 49(10):1511–1516

Chaudhuri KR, Healy DG, Schapira AH (2017) Non-motor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol 5(3):235–245

Da SF, Iop RD, Vietta GG et al (2016) microRNAs involved in Parkinson's disease: a systematic review. Mol Med Rep 14(5):4015–4022

Delavar MR, Baghi M, Yadegari E, Ghaedi K. Bioinformatic Prediction and Introducing of Some Targeting MicroRNAs of Sirt1 and Bcl2 Genes in Model of Parkinson's Disease. Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk. 2017

Dong S, Huiqing Y, Cuicui D et al (2017) Corrigendum to “Predictive value of plasma MicroRNA-216a/b in the diagnosis of esophageal squamous cell carcinoma”. Dis Markers 2017:1–2

Dunnewold RJ, Jacobi CE, van Hilten JJ (2018) Quantitative assessment of bradykinesia in patients with Parkinson's disease. J Clin Neurosurg 74(1):107

Falco MD, Luca LD, Acanfora F et al (2001) Alteration of the Bcl-2 : Bax Ratio in the placenta as pregnancy proceeds. Histochem J 33(7):421–425

Falup-Pecurariu C, Diaconu Ş (2017) Sleep dysfunction in Parkinson's disease. Int Rev Neurobiol 47(1):35

Guénin S, Mauriat M, Pelloux J, Wuytswinkel OV, Bellini C, Gutierrez L (2009) Normalization of qRT-PCR data: the necessity of adopting a systematic, experimental conditions-specific, validation of references. J Exp Bot 60(2):487–493

Harraz MM, Dawson TM, Dawson VL (2012) MicroRNAs in Parkinson's disease. J Chem Neuroanat 46(2):279–284

Hartmann A, Michel PP, Troadec JD et al (2001) Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?&nbsp. J Neurochem 76(6):1785–1793

He X, Yu Y, Awatramani R, Lu QR (2012) Unwrapping myelination by microRNAs. Neuroscientist 18(1):45

Jung YW, Zindl CL, Lai JF, Weaver CT, Chaplin DD (2010) MMP induced by Gr-1+ cells are crucial for recruitment of Th cells into the airways. Eur J Immunol 39(8):2281–2292

Kim C, Ojoamaize E, Spencer B et al (2015) Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson’s disease. J Neuroinflammation 12(1):236

Kuhar MJ, Yoho LL (2015) CART peptide analysis by Western blotting. Synapse 33(3):163–171

Leggio L, Vivarelli S, L'Episcopo F et al (2017) microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches. Int J Mol Sci 18(12):2698

Lewis TB, Glasgow JN, Harms AS, Standaert DG, Curiel DT (2014) Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy. Viruses 6(8):3293–3310

Liu C, Xi G, Yan P, Zhang W, Tang Y (2004) Effect of scorpion venom on the expression of Bcl-2/Bax in dopaminergic neurons of PD mice. Neuroscientist 24:623–628

Marconi R, Lefebvrecaparros D, Bonnet AM, Vidailhet M, Dubois B, Agid Y (2010) Levodopa-induced dyskinesias in Parkinson's disease phenomenology and pathophysiology. Mov Disord 9(1):2–12

Mei JM, Niu CS (2014) Effects of CDNF on 6-OHDA-induced apoptosis in PC12 cells via modulation of Bcl-2/Bax and caspase-3 activation. Neurol Sci 35(8):1275–1280

Menghini R, Casagrande V, Marino A et al (2017) MiR-216a: a link between endothelial dysfunction and autophagy. Cell Death Dis 5(1):e1029

Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O'Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 105(30):10513–10518

O'Connor L, Strasser A, O'Reilly LA et al (2014) Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 17(2):384–395

Onyango IG (2008) Mitochondrial dysfunction and oxidative stress in Parkinson’s disease. Neurochem Res 33(3):589–597

Pang X, Hogan EM, Casserly A, Gao G, Gardner PD, Tapper AR (2014) Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival. Mol Cell Neurosci 58(1):22–28

Reed JC (2006) Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities. Cell Death Differ 13(8):1378–1386

Rodriguezoroz MC, Jahanshahi M, Krack P et al (2009) Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms. Lancet Neurol 8(12):1128–1139

Singleton AB, Farrer M, Johnson J et al (2003) Alpha-Synuclein locus triplication causes Parkinson's disease. Science 302(5646):841–841

Staudt MD, Di SA, Xu H et al (2015) Advances in Neurotrophic factor and cell-based therapies for Parkinson's disease: a mini-review. Gerontology 62(3):371–380

Suh DC, Pahwa R, Mallya U (2012) Treatment patterns and associated costs with Parkinson's disease levodopa induced dyskinesia. J Neurol Sci 319(1–2):24–31

Titzedealmeida R, Titzedealmeida SS (2018) miR-7 replacement therapy in Parkinson's disease. Curr Gene Ther 18(3):143–153

Tolosa E, Bottaorfila T, Morató X et al (2018) MicroRNA alterations in iPSC-derived dopaminergic neurons from Parkinson disease patients. Neurobiol Aging 4(5):eaao5553

Wang Z, Li Y, Kong D, Ahmad A, Banerjee S, Sarkar FH (2010) Cross-talk between miRNA and notch signaling pathways in tumor development and progression. Cancer Lett 292(2):141–148

Wang DB, Uo T, Kinoshita C et al (2017) Bax interacting Factor-1 promotes survival and mitochondrial elongation in neurons. J Neurosci the Official Journal of the Society for Neuroscience 34(7):2674–2683

Willis AW, Schootman M, Kung N, Racette BA (2013) Epidemiology and neuropsychiatric manifestations of young onset Parkinson’s disease in the United States. Parkinsonism Relat Disord 19(2):202–206

Xiao M, Li J, Li W, Wang Y, Wu F, Xi Y, Zhang L, Ding C, Luo H, Li Y, Peng L, Zhao L, Peng S, Xiao Y, Dong S, Cao J, Yu W (2017) MicroRNAs activate gene transcription epigenetically as an enhancer trigger. RNA Biol 14(10):1326–1334

Xie Y, Chen Y (2016) microRNAs: emerging targets regulating oxidative stress in the models of Parkinson's disease. Front Neurosci 10

Yang B, Gao G, Wang Z, et al (2018) Long non-coding RNA HOTTIP promotes prostate cancer cells proliferation and migration by sponging miR-216a-5p. Biosci Rep 38(5):BSR20180566

Zhao N, Jin L, Fei G, Zheng Z, Zhong C (2014) Serum microRNA-133b is associated with low ceruloplasmin levels in Parkinson's disease. Parkinsonism Relat Disord 20(11):1177–1180

Zou XZ, Liu T, Gong ZC, Hu CP, Zhang Z (2017) MicroRNAs-mediated epithelial-mesenchymal transition in fibrotic diseases. Eur J Pharmacol 796:190–206