MicroRNA-10a-5p targets SERPINE1 to suppress cell progression and epithelial–mesenchymal transition process in clear cell renal cell carcinoma

Molecular & Cellular Toxicology - Tập 20 Số 1 - Trang 75-84 - 2024
Jian Chang1, Guiling Xiao1, Weifeng Zhu1, Mengyu Ding1, Hui Liu1, Qiong Wang1
1Affiliated Hospital of Shaoxing University, NO. 999 Zhongxing South Road, Yuecheng District, Shaoxing, 312000, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

Akula SM, Ruvolo PP, McCubrey JA (2020) TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer. Aging 12:2777–2797. https://doi.org/10.18632/aging.102776

Arai T et al (2017) Regulation of spindle and kinetochore-associated protein 1 by antitumor miR-10a-5p in renal cell carcinoma. Cancer Sci 108:2088–2101. https://doi.org/10.1111/cas.13331

Barbato S, Solaini G, Fabbri M (2017) MicroRNAs in oncogenesis and tumor suppression. Int Rev Cell Mol Biol 333:229–268. https://doi.org/10.1016/bs.ircmb.2017.05.001

Bindayi A et al (2018) Neoadjuvant therapy for localized and locally advanced renal cell carcinoma. Urol Oncol 36:31–37. https://doi.org/10.1016/j.urolonc.2017.07.015

Courthod G, Franco P, Palermo L, Pisconti S, Numico G (2014) The role of microRNA in head and neck cancer: current knowledge and perspectives. Molecules 19:5704–5716. https://doi.org/10.3390/molecules19055704

Duran I et al (2017) Resistance to targeted therapies in renal cancer: the importance of changing the mechanism of action. Target Oncol 12:19–35. https://doi.org/10.1007/s11523-016-0463-4

Ferlay J et al (2015) Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136:E359-386. https://doi.org/10.1002/ijc.29210

Hsieh JJ et al (2017) Renal cell carcinoma. Nat Rev Dis Primers 3:17009. https://doi.org/10.1038/nrdp.2017.9

Hu B et al (2021) MicroRNA-148a-3p ZRGETS SERPINE1 to suppress EMT-mediated colon adenocarcinoma progression. Cancer Manag Res 13:6349–6362. https://doi.org/10.2147/cmar.S302777

Kim JE et al (2018) Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway. Sci Rep 8:12407. https://doi.org/10.1038/s41598-018-30530-6

Klimczak-Bitner AA, Kordek R, Bitner J, Musial J, Szemraj J (2016) Expression of MMP9, SERPINE1 and miR-134 as prognostic factors in esophageal cancer. Oncol Lett 12:4133–4138. https://doi.org/10.3892/ol.2016.5211

Kong HJ et al (2021) Crosstalk between YAP and TGFbeta regulates SERPINE1 expression in mesenchymal lung cancer cells. Int J Oncol 58:111–121. https://doi.org/10.3892/ijo.2020.5153

Kowalik CG et al (2017) Profiling microRNA from nephrectomy and biopsy specimens: predictors of progression and survival in clear cell renal cell carcinoma. BJU Int 120:428–440. https://doi.org/10.1111/bju.13886

Lu Y et al (2017) Direct targeting of MAPK8IP1 by miR-10a-5p is a major mechanism for gastric cancer metastasis. Oncol Lett 13:1131–1136. https://doi.org/10.3892/ol.2016.5544

Philips GK, Atkins MB (2014) New agents and new targets for renal cell carcinoma. Am Soc Clin Oncol Educ Book. https://doi.org/10.14694/EdBook_AM.2014.34.e222

Qin Z (2021) J Cell Mol Med 25:2734. https://doi.org/10.1111/jcmm.16354

Rini BI, Campbell SC, Escudier B (2009) Renal cell carcinoma. Lancet 373:1119–1132. https://doi.org/10.1016/S0140-6736(09)60229-4

Tsukigi M et al (2012) Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3beta. Cancer Lett 315:189–197. https://doi.org/10.1016/j.canlet.2011.10.008

Wu Y et al (2019) LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells. Cancer Sci 110:973–984. https://doi.org/10.1111/cas.13950

Yang JD, Ma L, Zhu Z (2019) SERPINE1 as a cancer-promoting gene in gastric adenocarcinoma: facilitates tumour cell proliferation, migration, and invasion by regulating EMT. J Chemother 31:408–418. https://doi.org/10.1080/1120009X.2019.1687996

Zhai L, Li Y, Lan X, Ai L (2017) MicroRNA-10a-5p suppresses cancer proliferation and division in human cervical cancer by targeting BDNF. Exp Ther Med 14:6147–6151. https://doi.org/10.3892/etm.2017.5312

Zhang L et al (2013) The complex roles of microRNAs in the metastasis of renal cell carcinoma. J Nanosci Nanotechnol 13:3195–3203. https://doi.org/10.1166/jnn.2013.6712

Zhang J et al (2019) S-equol inhibits proliferation and promotes apoptosis of human breast cancer MCF-7cells via regulating miR-10a-5p and PI3K/AKT pathway. Arch Biochem Biophys 672:108064. https://doi.org/10.1016/j.abb.2019.108064

Zhang Q, Lei L, Jing D (2020) Knockdown of SERPINE1 reverses resistance of triplenegative breast cancer to paclitaxel via suppression of VEGFA. Oncol Rep 44:1875–1884. https://doi.org/10.3892/or.2020.7770