Micro-percutaneous nephrolithotomy in infants: a single-center experience

Onur Dede1, Ahmet Ali Sancaktutar1, Okan Baş2, Mansur Dağgüllu1, Mazhar Utangaç1, Necmettin Penbegul1, Haluk Soylemez3, Namık Kemal Hatipoglu1, Mehmet Nuri Bodakci1, Yaşar Bozkurt1, Murat Atar1, Gülay Dede4
1Department of Urology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey
2Department of Urology, Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey
3Department of Urology, Faculty of Medicine, Hacettepe University, Ankara, Turkey,
4Department of Clinical Microbiology and Infectious Diseases, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey

Tóm tắt

This study aimed to investigate the effectiveness and reliability of micro-percutaneous nephrolithotomy (micro-PNL) for the management of kidney stones in pediatric patients. This retrospective study included 24 infants that underwent micro-PNL for renal stones between March 2012 and April 2015. The inclusion criteria included: age younger than 2 years, stone size <20 mm, absence of urinary tract malformations and active infection, and no coagulopathy. Stone-free rates were assessed one month postoperatively by ultrasonography (USG) and kidneys, ureters, bladder (KUB) radiography. Complications were classified according to the Clavien classification system. The mean age of the patients was 15.8 ± 7.8 months (range, 8–23) and the mean stone size was 13.5 ± 3.84 mm. Intra-renal access was achieved using USG in 11 patients and KUB fluoroscopy in 13 patients. The operation time and fluoroscopic screening time were 53.7 ± 10.35 and 1.4 ± 0.9 min, respectively. The mean hospital stay was 2.5 ± 0.8 days, and the mean drop in the hemoglobin level was 0.51 ± 0.34 g/dL. Bleeding requiring blood transfusion was not observed. A ureteral J stent was implanted perioperatively in four patients because of stone burden. Four patients complained of postoperative renal colic (Clavien grade 1) and postoperative fever was observed in two patients. Definitive success rates were as follows: the stone-free rate was 83.3 % (n = 20) and residual fragments were observed in four patients.

Từ khóa


Tài liệu tham khảo

Muslumanoglu AY, Tefekli A, Sarilar O, Binbay M, Altunrende F, Ozkuvanci U (2003) Extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: a large scale retrospective analysis. J Urol 170(6 Pt 1):2405–2408. doi:10.1097/01.ju.0000096422.72846.80

Hatipoglu NK, Tepeler A, Buldu I, Atis G, Bodakci MN, Sancaktutar AA, Silay MS, Daggulli M, Istanbulluoglu MO, Karatag T, Gurbuz C, Armagan A, Caskurlu T (2014) Initial experience of micro-percutaneous nephrolithotomy in the treatment of renal calculi in 140 renal units. Urolithiasis 42(2):159–164. doi:10.1007/s00240-013-0631-2

Atar M, Sancaktutar AA, Penbegul N, Soylemez H, Bodakci MN, Hatipoglu NK, Bozkurt Y, Cakmakci S (2012) Comparison of a 4.5 F semi-rigid ureteroscope with a 7.5 F rigid ureteroscope in the treatment of ureteral stones in preschool-age children. Urol Res 40(6):733–738. doi:10.1007/s00240-012-0489-8

Unsal A, Resorlu B, Kara C, Bozkurt OF, Ozyuvali E (2010) Safety and efficacy of percutaneous nephrolithotomy in infants, preschool age, and older children with different sizes of instruments. Urology 76(1):247–252. doi:10.1016/j.urology.2009.08.087

Tepeler A, Armagan A, Sancaktutar AA, Silay MS, Penbegul N, Akman T, Hatipoglu NK, Ersoz C, Erdem MR, Akcay M (2013) The role of microperc in the treatment of symptomatic lower pole renal calculi. J Endourol Soc 27(1):13–18. doi:10.1089/end.2012.0422

Desai MR, Sharma R, Mishra S, Sabnis RB, Stief C, Bader M (2011) Single-step percutaneous nephrolithotomy (microperc): the initial clinical report. J Urol 186(1):140–145. doi:10.1016/j.juro.2011.03.029

Penbegul N, Bodakci MN, Hatipoglu NK, Sancaktutar AA, Atar M, Cakmakci S, Yildirim K (2013) Microsheath for microperc: 14-gauge angiocath. J Endourol Soc 27(7):835–839. doi:10.1089/end.2012.0737

Piskin MM, Guven S, Kilinc M, Arslan M, Goger E, Ozturk A (2012) Preliminary, favorable experience with microperc in kidney and bladder stones. J Endourol Soc 26(11):1443–1447. doi:10.1089/end.2012.0333

Unsal A, Resorlu B (2011) Retrograde intrarenal surgery in infants and preschool-age children. J Pediatr Surg 46(11):2195–2199. doi:10.1016/j.jpedsurg.2011.07.013

Bodakci MN, Daggulli M, Sancaktutar AA, Soylemez H, Hatipoglu NK, Utangac MM, Penbegul N, Ziypak T, Bozkurt Y (2014) Minipercutaneous nephrolithotomy in infants: a single-center experience in an endemic region in Turkey. Urolithiasis 42(5):427–433. doi:10.1007/s00240-014-0677-9

Thomas JC, DeMarco RT, Donohoe JM, Adams MC, Brock JW 3rd, Pope JC (2005) Pediatric ureteroscopic stone management. J Urol 174(3):1072–1074. doi:10.1097/01.ju.0000169159.42821.bc

Wadhwa P, Aron M, Seth A, Dogra PN, Hemal AK, Gupta NP (2007) Pediatric shockwave lithotripsy: size matters! J Endourol Soc 21(2):141–144. doi:10.1089/end.2006.0245

Bruce RG, el-Galley RE, Wells J, Galloway NT (1999) Antegrade continence enema for the treatment of fecal incontinence in adults: use of gastric tube for catheterizable access to the descending colon. J Urol 161(6):1813–1816

Resorlu B, Oguz U, Resorlu EB, Oztuna D, Unsal A (2012) The impact of pelvicaliceal anatomy on the success of retrograde intrarenal surgery in patients with lower pole renal stones. Urology 79(1):61–66. doi:10.1016/j.urology.2011.06.031

Dave S, Khoury AE, Braga L, Farhat WA (2008) Single-institutional study on role of ureteroscopy and retrograde intrarenal surgery in treatment of pediatric renal calculi. Urology 72(5):1018–1021. doi:10.1016/j.urology.2008.03.065

Manohar T, Ganpule AP, Shrivastav P, Desai M (2006) Percutaneous nephrolithotomy for complex caliceal calculi and staghorn stones in children less than 5 years of age. J Endourol Soc 20(8):547–551. doi:10.1089/end.2006.20.547

Gunes A, Yahya Ugras M, Yilmaz U, Baydinc C, Soylu A (2003) Percutaneous nephrolithotomy for pediatric stone disease–our experience with adult-sized equipment. Scand J Urol Nephrol 37(6):477–481. doi:10.1080/00365590310001755

Sabnis RB, Ganesamoni R, Ganpule AP, Mishra S, Vyas J, Jagtap J, Desai M (2013) Current role of microperc in the management of small renal calculi. Indian J Urol 29(3):214–218. doi:10.4103/0970-1591.117282

Bilen CY, Kocak B, Kitirci G, Ozkaya O, Sarikaya S (2007) Percutaneous nephrolithotomy in children: lessons learned in 5 years at a single institution. J Urol 177(5):1867–1871. doi:10.1016/j.juro.2007.01.052

Penbegul N, Tepeler A, Sancaktutar AA, Bozkurt Y, Atar M, Yildirim K, Soylemez H (2012) Safety and efficacy of ultrasound-guided percutaneous nephrolithotomy for treatment of urinary stone disease in children. Urology 79(5):1015–1019. doi:10.1016/j.urology.2011.10.059

Guven S, Istanbulluoglu O, Gul U, Ozturk A, Celik H, Aygun C, Ozdemir U, Ozturk B, Ozkardes H, Kilinc M (2011) Successful percutaneous nephrolithotomy in children: multicenter study on current status of its use, efficacy and complications using Clavien classification. J Urol 185(4):1419–1424. doi:10.1016/j.juro.2010.11.055

Kukreja R, Desai M, Patel S, Bapat S, Desai M (2004) Factors affecting blood loss during percutaneous nephrolithotomy: prospective study. J Endourol Soc 18(8):715–722. doi:10.1089/end.2004.18.715

Armagan A, Tepeler A, Silay MS, Ersoz C, Akcay M, Akman T, Erdem MR, Onol SY (2013) Micropercutaneous nephrolithotomy in the treatment of moderate-size renal calculi. J Endourol Soc 27(2):177–181. doi:10.1089/end.2012.0517

Roberts S, Bolton DM, Stoller ML (1994) Hypothermia associated with percutaneous nephrolithotomy. Urology 44(6):832–835