Mice deficient for 5-lipoxygenase, but not leukocyte-type 12-lipoxygenase, display altered immune responses during infection with Schistosoma mansoni

Wynn, 1995, An IL-12 based vaccination method for preventing fibrosis induced by schistosome infection, Nature, 376, 594, 10.1038/376594a0 Wynn, 1993, Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni, J Immunol, 151, 1430, 10.4049/jimmunol.151.3.1430 Chensue, 1983, Production of superoxide anion, prostaglandins, and hydroxyeicosatetraenoic acids by macrophages from hypersensitivity-type (Schistosoma mansoni egg) and foreign body-type granulomas, Infect Immun, 42, 1116, 10.1128/iai.42.3.1116-1125.1983 Kunkel, 1984, Role of lipoxygenase products in murine pulmonary granuloma formation, J Clin Invest, 74, 514, 10.1172/JCI111449 Kunkel, 1984, Macrophage function in the Schistosoma mansoni egg-induced pulmonary granuloma. Role of arachidonic acid metabolites in macrophage Ia antigen expression, Am J Pathol, 114, 240 Rand, 1982, Arachidonic acid metabolism of the murine eosinophil. II. Involvement of the lipoxygenase pathway in the response to the lymphokine eosinophil stimulation promoter, J Immunol, 129, 1239, 10.4049/jimmunol.129.3.1239 Rand, 1983, Arachidonic acid metabolism of the murine eosinophil. III. Effect of nonsteroid anti-inflammatory drugs on lymphokine-directed eosinophil migration in vivo, J Immunol, 130, 1356, 10.4049/jimmunol.130.3.1356 Turk, 1983, Identification of lipoxygenase products from arachidonic acid metabolism in stimulated murine eosinophils, Biochim Biophys Acta, 750, 78, 10.1016/0005-2760(83)90206-0 Chen, 1994, Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene, Nature, 372, 179, 10.1038/372179a0 Sun, 1996, Targeted disruption of the 12/15-lipoxygenase expression in peritoneal macrophages, J Biol Chem, 271, 24055, 10.1074/jbc.271.39.24055 Colley, 1975, Immune responses to a soluble egg antigen preparation during chronic primary infection with Schistosoma mansoni, J Immunol, 115, 150, 10.4049/jimmunol.115.1.150 Colley, 1972, Intradermal immune responses to a schistosomal egg antigen during experimental murine Schistosoma mansoni infection, Proc Soc Exp Biol Med, 140, 772, 10.3181/00379727-140-36550 Secor, 1990, Eosinophils and immune mechanisms. VI. The synergistic combination of granulocyte-macrophage colony-stimulating factor and IL-5 accounts for eosinophil-stimulation promoter activity in Schistosoma mansoni-infected mice, J Immunol, 144, 1484, 10.4049/jimmunol.144.4.1484 Barsoum, 1990, Schistosoma mansoni: Detection of circulating antigens in murine schistosomiasis by antigen capture sandwich ELISA using a monoclonal antibody, Exp Parasitol, 71, 107, 10.1016/0014-4894(90)90013-3 Svetic, 1991, Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody, J Immunol, 147, 2391, 10.4049/jimmunol.147.7.2391 Wynn, 1994, Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology, J Exp Med, 179, 1551, 10.1084/jem.179.5.1551 Eltoum, 1995, Suppressive effect of interleukin-4 (IL-4) neutralization differs for granulomas around Schistosoma mansoni eggs injected into mice compared with those around eggs laid in infected mice, Infect Immun, 63, 2532, 10.1128/iai.63.7.2532-2536.1995 Pearce, 1996, Schistosoma mansoni in IL-4-deficient mice, Int Immunol, 8, 435, 10.1093/intimm/8.4.435 Stadecker, 1994, The shrinking schistosomal egg granuloma, Exp Parasitol, 79, 198, 10.1006/expr.1994.1080 Lu, 1998, Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice, J Exp Med, 187, 601, 10.1084/jem.187.4.601 Funk, 1996, The molecular biology of mamalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice, Biochim Biophys Acta, 1304, 65, 10.1016/S0005-2760(96)00107-5 Nakamura, 1995, Immunocytochemical localization of platelet-type arachidonate 12-lipoxygenase in mouse blood cells, J Histochem Cytochem, 43, 237, 10.1177/43.3.7868854