MiR-200, a new star miRNA in human cancer

Cancer Letters - Tập 344 Số 2 - Trang 166-173 - 2014
Xiangling Feng1, Zhengming Wang1, Rebecca A. Fillmore2, Yaguang Xi1
1Mitchell Cancer Institute, University of South Alabama, United States
2Department of Biological Sciences, University of Southern Mississippi Gulf Coast, United States

Tóm tắt

Từ khóa


Tài liệu tham khảo

Ambros, 2001, MicroRNAs: tiny regulators with great potential, Cell, 107, 823, 10.1016/S0092-8674(01)00616-X

Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5

Lee, 2004, MicroRNA genes are transcribed by RNA polymerase II, EMBO J., 23, 4051, 10.1038/sj.emboj.7600385

Borchert, 2006, RNA polymerase III transcribes human microRNAs, Natl. Struct. Mol. Biol., 13, 1097, 10.1038/nsmb1167

Lee, 2003, The nuclear RNase III Drosha initiates microRNA processing, Nature, 425, 415, 10.1038/nature01957

Lund, 2004, Nuclear export of microRNA precursors, Science, 303, 95, 10.1126/science.1090599

Yi, 2003, Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs, Genes Dev., 17, 3011, 10.1101/gad.1158803

Bohnsack, 2004, Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs, RNA, 10, 185, 10.1261/rna.5167604

Bernstein, 2001, Role for a bidentate ribonuclease in the initiation step of RNA interference, Nature, 409, 363, 10.1038/35053110

Grishok, 2001, Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing, Cell, 106, 23, 10.1016/S0092-8674(01)00431-7

Hutvagner, 2001, A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA, Science, 293, 834, 10.1126/science.1062961

Ketting, 2001, Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans, Genes Dev., 15, 2654, 10.1101/gad.927801

Knight, 2001, A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans, Science, 293, 2269, 10.1126/science.1062039

Mourelatos, 2002, MiRNPs: a novel class of ribonucleoproteins containing numerous microRNAs, Genes Dev., 16, 720, 10.1101/gad.974702

Valencia-Sanchez, 2006, Control of translation and mRNA degradation by miRNAs and siRNAs, Genes Dev., 20, 515, 10.1101/gad.1399806

Lewis, 2005, Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets, Cell, 120, 15, 10.1016/j.cell.2004.12.035

Uhlmann, 2010, MiR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer, Oncogene, 29, 4297, 10.1038/onc.2010.201

Choi, 2008, Members of the miRNA-200 family regulate olfactory neurogenesis, Neuron, 57, 41, 10.1016/j.neuron.2007.11.018

Cano, 2008, Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition, Trends Cell Biol., 18, 357, 10.1016/j.tcb.2008.05.005

Gregory, 2008, MicroRNAs as regulators of epithelial–mesenchymal transition, Cell Cycle, 7, 3112, 10.4161/cc.7.20.6851

Korpal, 2008, The emerging role of miR-200 family of microRNAs in epithelial–mesenchymal transition and cancer metastasis, RNA Biol., 5, 115, 10.4161/rna.5.3.6558

Mongroo, 2010, The role of the miR-200 family in epithelial–mesenchymal transition, Cancer Biol. Ther., 10, 219, 10.4161/cbt.10.3.12548

Brabletz, 2010, The ZEB/miR-200 feedback loop – a motor of cellular plasticity in development and cancer?, EMBO Rep., 11, 670, 10.1038/embor.2010.117

Hill, 2013, ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer, Int. J. Cancer, 132, 745, 10.1002/ijc.27708

Park, 2008, The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2, Genes Dev., 22, 894, 10.1101/gad.1640608

Gregory, 2008, The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1, Natl. Cell Biol., 10, 593, 10.1038/ncb1722

Korpal, 2008, The miR-200 family inhibits epithelial–mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2, J. Biol. Chem., 283, 14910, 10.1074/jbc.C800074200

Browne, 2010, ZEB proteins link cell motility with cell cycle control and cell survival in cancer, Cell Cycle, 9, 886, 10.4161/cc.9.5.10839

Wiklund, 2011, Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer, Int. J. Cancer, 128, 1327, 10.1002/ijc.25461

Aydogdu, 2012, MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer, Carcinogenesis, 33, 1502, 10.1093/carcin/bgs161

Castilla, 2012, MicroRNA-200 family modulation in distinct breast cancer phenotypes, PLoS One, 7, e47709, 10.1371/journal.pone.0047709

Gravgaard, 2012, The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer, Breast Cancer Res. Treat, 134, 207, 10.1007/s10549-012-1969-9

Hur, 2013, MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis, Gut, 62, 1315, 10.1136/gutjnl-2011-301846

Paterson, 2013, Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression, Neoplasia, 15, 180, 10.1593/neo.121828

van Kempen, 2012, Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression, Virchows Arch., 461, 441, 10.1007/s00428-012-1309-9

Lee, 2011, The expression of the miRNA-200 family in endometrial endometrioid carcinoma, Gynecol. Oncol., 120, 56, 10.1016/j.ygyno.2010.09.022

Snowdon, 2011, The microRNA-200 family is upregulated in endometrial carcinoma, PLoS One, 6, e22828, 10.1371/journal.pone.0022828

Du, 2009, Down-regulation of miR-141 in gastric cancer and its involvement in cell growth, J. Gastroenterol, 44, 556, 10.1007/s00535-009-0037-7

Kurashige, 2012, MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma, Ann. Surg. Oncol., 19, S656, 10.1245/s10434-012-2217-6

Shinozaki, 2010, Downregulation of microRNA-200 in EBV-associated gastric carcinoma, Cancer Res., 70, 4719, 10.1158/0008-5472.CAN-09-4620

Valladares-Ayerbes, 2012, Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer, J. Transl. Med., 10, 186, 10.1186/1479-5876-10-186

Ladeiro, 2008, MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations, Hepatology, 47, 1955, 10.1002/hep.22256

Pacurari, 2013, The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells, Int. J. Oncol., 43, 548, 10.3892/ijo.2013.1963

Xia, 2010, MiR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion, Biochem. Biophys. Res. Commun., 391, 535, 10.1016/j.bbrc.2009.11.093

Wiklund, 2011, MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma, PLoS One, 6, e27840, 10.1371/journal.pone.0027840

Bendoraite, 2010, Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition, Gynecol. Oncol., 116, 117, 10.1016/j.ygyno.2009.08.009

Hu, 2009, A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer, Gynecol. Oncol., 114, 457, 10.1016/j.ygyno.2009.05.022

Leskela, 2011, The miR-200 family controls beta-tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients, Endocrinol. Relat. Cancer, 18, 85, 10.1677/ERC-10-0148

Mateescu, 2011, MiR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response, Natl. Med., 17, 1627, 10.1038/nm.2512

Nam, 2008, MicroRNA expression profiles in serous ovarian carcinoma, Clin. Cancer Res., 14, 2690, 10.1158/1078-0432.CCR-07-1731

Prislei, 2013, MiR-200c and HuR in ovarian cancer, BMC Cancer, 13, 72, 10.1186/1471-2407-13-72

Li, 2010, Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels, Cancer Res., 70, 5226, 10.1158/0008-5472.CAN-09-4227

Gee, 2010, Downregulated microRNAs in the differential diagnosis of malignant pleural mesothelioma, Int. J. Cancer, 127, 2859, 10.1002/ijc.25285

Barron, 2012, Biochemical relapse following radical prostatectomy and miR-200a levels in prostate cancer, Prostate, 72, 1193, 10.1002/pros.22469

Castro-Vega, 2013, Telomere crisis in kidney epithelial cells promotes the acquisition of a microRNA signature retrieved in aggressive renal cell carcinomas, Carcinogenesis, 34, 1173, 10.1093/carcin/bgt029

Zidar, 2011, Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck–hallmark of epithelial–mesenchymal transition, Hum. Pathol., 42, 482, 10.1016/j.humpath.2010.07.020

Braun, 2010, Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas, Oncogene, 29, 4237, 10.1038/onc.2010.169

Cheng, 2011, Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis, PLoS One, 6, e17745, 10.1371/journal.pone.0017745

Liu, 2012, High expression of serum miR-21 and tumor miR-200c associated with poor prognosis in patients with lung cancer, Med. Oncol., 29, 618, 10.1007/s12032-011-9923-y

Yu, 2010, MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation, Mol. Cancer, 9, 169, 10.1186/1476-4598-9-169

Olson, 2009, MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer, Genes Dev., 23, 2152, 10.1101/gad.1820109

Gibbons, 2009, Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression, Genes Dev., 23, 2140, 10.1101/gad.1820209

Chen, 2011, Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells, Gynecol. Oncol., 121, 200, 10.1016/j.ygyno.2010.12.339

Yu, 2010, MicroRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling, Proc. Natl. Acad. Sci. USA, 107, 8231, 10.1073/pnas.1002080107

Brabletz, 2011, The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells, EMBO J., 30, 770, 10.1038/emboj.2010.349

Vallejo, 2011, Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells, EMBO J, 30, 756, 10.1038/emboj.2010.358

Yang, 2011, The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice, J. Clin. Invest., 121, 1373, 10.1172/JCI42579

Dykxhoorn, 2009, MiR-200 enhances mouse breast cancer cell colonization to form distant metastases, PLoS One, 4, e7181, 10.1371/journal.pone.0007181

Shimono, 2009, Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells, Cell, 138, 592, 10.1016/j.cell.2009.07.011

Iliopoulos, 2010, Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells, Mol. Cell, 39, 761, 10.1016/j.molcel.2010.08.013

Lim, 2013, Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state, J. Cell Sci., 126, 2256, 10.1242/jcs.122275

Lin, 2009, Myc-regulated microRNAs attenuate embryonic stem cell differentiation, EMBO J., 28, 3157, 10.1038/emboj.2009.254

Wang, 2013, Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation, Proc. Natl. Acad. Sci. USA, 110, 2858, 10.1073/pnas.1212769110

Peng, 2012, A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation, J. Neurosci., 32, 13292, 10.1523/JNEUROSCI.2124-12.2012

Samavarchi-Tehrani, 2010, Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming, Cell Stem Cell, 7, 64, 10.1016/j.stem.2010.04.015

Xia, 2010, MicroRNA-200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells, Mol. Cell Biochem., 344, 261, 10.1007/s11010-010-0550-2

Yao, 2013, MiR-200b targets GATA-4 during cell growth and differentiation, RNA Biol., 10, 465, 10.4161/rna.24370

Schickel, 2010, MiR-200c regulates induction of apoptosis through CD95 by targeting FAP-1, Mol. Cell, 38, 908, 10.1016/j.molcel.2010.05.018

Magenta, 2011, MiR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition, Cell Death Differen., 18, 1628, 10.1038/cdd.2011.42

Meng, 2006, Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines, Gastroenterology, 130, 2113, 10.1053/j.gastro.2006.02.057

Ali, 2010, Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF, Cancer Res., 70, 3606, 10.1158/0008-5472.CAN-09-4598

Cochrane, 2010, Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers, J. Oncol., 2010, 821717, 10.1155/2010/821717

Pogribny, 2010, Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin, Int. J. Cancer, 127, 1785, 10.1002/ijc.25191

Chen, 2012, Down-regulation of microRNA-200c is associated with drug resistance in human breast cancer, Med. Oncol., 29, 2527, 10.1007/s12032-011-0117-4

Rui, 2010, Identification of microRNA profiles in docetaxel-resistant human non-small cell lung carcinoma cells (SPC-A1), J. Cell Mol. Med., 14, 206, 10.1111/j.1582-4934.2009.00964.x

Feng, 2012, MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3, Cancer, 118, 3365, 10.1002/cncr.26560

Adam, 2009, MiR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy, Clin. Cancer Res., 15, 5060, 10.1158/1078-0432.CCR-08-2245

Zhu, 2012, MiR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP, Cancer Chemother. Pharmacol., 69, 723, 10.1007/s00280-011-1752-3

Burk, 2008, A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells, EMBO Rep., 9, 582, 10.1038/embor.2008.74

Bracken, 2008, A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial–mesenchymal transition, Cancer Res., 68, 7846, 10.1158/0008-5472.CAN-08-1942

Liu, 2013, MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms, Oncogene, 32, 296, 10.1038/onc.2012.58

Gill, 2011, Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs, Stem Cells, 29, 764, 10.1002/stem.628

Mizuguchi, 2012, Cooperation of p300 and PCAF in the control of microRNA 200c/141 transcription and epithelial characteristics, PLoS One, 7, e32449, 10.1371/journal.pone.0032449

Pieraccioli, 2013, Activation of miR200 by c-Myb depends on ZEB1 expression and miR200 promoter methylation, Cell Cycle, 12, 2309, 10.4161/cc.25405

Cesi, 2011, TGFbeta-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells, Cell Cycle, 10, 4149, 10.4161/cc.10.23.18346

Roy, 2013

Kim, 2011, P53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2, J. Exp. Med., 208, 875, 10.1084/jem.20110235

Knouf, 2012, An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription, Nucl. Acid. Res., 40, 499, 10.1093/nar/gkr731

Ahn, 2012, Smad3 regulates E-cadherin via miRNA-200 pathway, Oncogene, 31, 3051, 10.1038/onc.2011.484

Bai, 2013, Tamoxifen represses miR-200 microRNAs and promotes epithelial-to-mesenchymal transition by up-regulating c-Myc in endometrial carcinoma cell lines, Endocrinology, 154, 635, 10.1210/en.2012-1607

Vrba, 2010, Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells, PLoS One, 5, e8697, 10.1371/journal.pone.0008697

Yu, 2013, Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the microRNA200 gene family, Int. J. Cancer, 133, 1368, 10.1002/ijc.28151

Tellez, 2011, EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells, Cancer Res., 71, 3087, 10.1158/0008-5472.CAN-10-3035

Zhang, 2013, Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma, Carcinogenesis, 34, 577, 10.1093/carcin/bgs381

Manavalan, 2013, Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells, PLoS One, 8, e62334, 10.1371/journal.pone.0062334

Iliopoulos, 2009, MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells, Sci. Signal, 2, 10.1126/scisignal.2000356

Virtakoivu, 2012, Distinct roles of AKT isoforms in regulating beta1-integrin activity, migration, and invasion in prostate cancer, Mol. Biol. Cell, 23, 3357, 10.1091/mbc.E12-03-0213