Methotrexate toxicity: Correlation with duration of administration, plasma levels, dose and excretion pattern
Tóm tắt
Từ khóa
Tài liệu tham khảo
Djerassi, 1967, Methotrexate infusions and intensive supportive care in the management of children with acute lymphocyte leukaemia: follow-up report, Cancer Res., 27, 2561
D. Bergsagel, Personal communication.
Mitchell, 1968, Effectiveness of high-dose infusions of methotrexate followed by leucovorin in carcinoma of the head and neck, Cancer Res., 28, 1088
Schwarzenberg, 1969, Une nouvelle combinaison de méthotrexate et d'acide folinique pour le traitment des cancers, Press. Méd., 77, 385
In Goodman and Gillman, 1970
Brodie, 1965, 58, 946
Burns, 1965, 58, 955
Fischer, 1959, Amethopterin-nutritional resistance characteristics of leukaemic clones, Cancer Res., 19, 372
Bertino, 1961, Increased activity of leukocyte dihydrofolic reductase in amethopterin-treated patients, Clinical Res., 9, 103
Fischer, 1961, Increased levels of folic acid reductase as a mechanism of resistance of amethopterin in leukaemic cells, Biochem. Pharmacol., 7, 75, 10.1016/0006-2952(61)90128-9
Jacobson, 1960, The inactivation of folic acid antagonists by normal and leukaemic cells, Biochem. Pharmacol., 5, 130, 10.1016/0006-2952(60)90015-0
Harrap, 1971, Mechanism of action of methotrexate: intrinsic and acquired drug resistance, Ann. N.Y. Acad. Sci., 186, 312, 10.1111/j.1749-6632.1971.tb46986.x
Bruce, 1966, Comparison of the sensitive of normal haemopoietic and transplanted lymphoma colony-forming cells to chemotherapeutic agents administered in vivo, J. Nat. Cancer Inst., 37, 233
Bertino, 1964, Techniques for study of resistance to folic acid antagonists, Meth. Red. Res., 10, 297