Metastatic renal cell carcinoma to the small bowel: three cases of GI bleeding and a literature review

Motzer RJ, Bander NH, Nanus DM. Renal-cell carcinoma. N Engl J Med. 1996;335:865–75.

Vani M, Nambiar A, Geetha K, Kundil B. Metastatic renal cell carcinoma causing small intestinal polyps with intussusception: a report of two cases. J Clin Diagn Res. 2017;11:13–5.

Medic I, Enriquez ML, Somer RA. Metastatic renal cell carcinoma to jejunum: an unusual case presentation. Urol Case Rep. 2017;18:34–6.

Gorski RL, Jalil SA, Razick M, Jalil AA. An obscure cause of gastrointestinal bleeding: Renal cell carcinoma metastasis to the small bowel. Int J Surg Case Rep. 2015;15:130–2.

Bellio G, Cipolat Mis T, Kaso G, Dattola R, Casagranda B, Bortul M. Small bowel intussusception from renal cell carcinoma metastasis: a case report and review of the literature. J Med Case Rep. 2016;10:222.

Ismali I, Neuen BL, Mantha M. Solitary jejunal metastasis from renal cell carcinoma presenting as small bowel obstruction 19 years after nephrectomy. BMJ Case Rep. 2015. https://doi.org/10.1136/bcr-2015-210857 .

Peery AF, Crockett SD, Barritt AS, Dellon ES, Eluri S, Gangarosa LM, Jensen ET, Lund JL, Pasricha S, Runge T, Schmidt M, Shaheen NJ, Sandler RS. Burden of gastrointestinal, liver, and pancreatic diseases in the United States. Gastroenterology. 2015;149(7):1731–41.

Rotondano G. Epidemiology and diagnosis of acute nonvariceal upper gastrointestinal bleeding. Gastroenterol Clin North Am. 2014;43:643–63.

Maluf-Fiho F, Martins BC, de Lima MS, Leonardo DV, Retes FA, Kawaguti FS, Sato CF, Hondo FY, Safatle-Ribeiro AV, Ribeiro U Jr. Etiology, endoscopic management and mortality of upper gastrointestinal bleeding in patients with cancer. United Eur Gastroenterol J. 2013;1:60–7.

Zuccaro G. Epidemiology of lower gastrointestinal bleeding. Best Pract Res Clin Gastroenterol. 2008;22:225–32.

Siegel RL, Miller KD, Jemal A. Cancer statistics 2015. CA Cancer J Clin. 2015;65:5–29.

Minardi AJ Jr, Zibari GB, Aultman DF, McMillan RW, McDonald JC. Small-bowel tumors. J Am Coll Surg. 1998;186:664–8.

Willis RA. The spread of tumours in the human body. Secondary tumours of the intestines. London: Butterworth & Co., Ltd; 1973. pp. 209–13.

Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, Chen I, Bycott PW, Baum CM, Figlin RA. Sunitinib versus interferon alpha in metastatic renal-cell carcinoma. N Eng J Med. 2007;356:115–24.

Park HJ, Kim HJ, Park SH, Lee JS, Kim AY, Ha HK. Gastrointestinal involvement of recurrent renal cell carcinoma: CT findings and clinicopathologic features. Korean J Radiol. 2017;18:452–60.

Mishra S, Hazra SP, Priyadarshi V, et al. Synchronous jejunal metastasis presenting as intussusception in a case of advanced RCC: a rare presentation. Indian J Surg. 2015;77:59–61.

Trojaniello C, Vitale MG, Trojaniello B, et al. Severe blood loss anaemia and recurrent intussusceptions as first presentation of bowel metastatic renal cell carcinoma: a case report and review of the literature. Mol Clin Oncol. 2017;7:654–60.