Metal-ion regulation of gene expression in yeast

Petris, 1996, Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane:a novel mechanism of regulated trafficking, EMBO J, 15, 6084, 10.1002/j.1460-2075.1996.tb00997.x

Hung, 1997, Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae, J Biol Chem, 272, 21461, 10.1074/jbc.272.34.21461

Botstein, 1997, Yeast as a model organism, Science, 277, 1259, 10.1126/science.277.5330.1259

Yuan, 1995, The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake, Proc Natl Acad Sci USA, 92, 2632, 10.1073/pnas.92.7.2632

Klomp, 1997, Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis, J Biol Chem, 272, 9221, 10.1074/jbc.272.14.9221

Amaravadi, 1997, Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment, Hum Genet, 99, 329, 10.1007/s004390050367

Zhou, 1997, hCTR1: a human gene for copper uptake identified by complementation in yeast, Proc Natl Acad Sci USA, 94, 7481, 10.1073/pnas.94.14.7481

Bacock, 1997, Regulation of mitochondrial iron accumulation by Yfh1, a putative homolog of frataxin, Science, 276, 1709, 10.1126/science.276.5319.1709

Dancis, 1994, The Saccharomyces cerevisiae copper transport protein (Ctr1p), J Biol Chem, 269, 25660, 10.1016/S0021-9258(18)47300-0

Yamaguchi-Iwai, 1995, AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae, EMBO J, 14, 1231, 10.1002/j.1460-2075.1995.tb07106.x

Stearman, 1996, A permease-oxidase complex involved in high-affinity iron uptake in yeast, Science, 271, 1552, 10.1126/science.271.5255.1552

Eide, 1996, The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation, Proc Natl Acad Sci USA, 93, 2354

Labbe, 1997, Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway, J Biol Chem, 272, 15951, 10.1074/jbc.272.25.15951

Yamaguchi-Iwai, 1997, Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1, J Biol Chem, 272, 17711, 10.1074/jbc.272.28.17711

Dancis, 1990, Ferric reductase of Saccharomyces cerevisiae: molecular characterization, role in iron uptake, and transcriptional control by iron, Proc Natl Acad Sci USA, 89, 3869, 10.1073/pnas.89.9.3869

Georgatsou, 1994, Two distinctly regulated genes are required for ferric reduction, the first step of iron uptake in Saccharomyces cerevisiae, Mol Cell Biol, 14, 3065, 10.1128/MCB.14.5.3065

Hassett, 1995, Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae, J Biol Chem, 270, 128, 10.1074/jbc.270.1.128

Lesuisse, 1996, Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transfer chain, J Biol Chem, 271, 13578, 10.1074/jbc.271.23.13578

Shatwell, 1996, The FRE1 ferric reductase of Saccharomyces cerevisiae is a cytochromeb similar to that of NADPH oxidase, J Biol Chem, 271, 14240, 10.1074/jbc.271.24.14240

Georgatsou, 1997, The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator, J Biol Chem, 272, 13786, 10.1074/jbc.272.21.13786

Yamaguchi-iwai, 1996, Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast, EMBO J, 15, 3377, 10.1002/j.1460-2075.1996.tb00703.x

De Silva, 1995, The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidase, J Biol Chem, 270, 1098, 10.1074/jbc.270.3.1098

DeSilva, 1997, Purification and characterization of Fet3 protein, a yeast homologue of ceruloplasmin, J Biol Chem, 272, 14208, 10.1074/jbc.272.22.14208

Zhao, 1996, The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae, J Biol Chem, 38, 23203, 10.1074/jbc.271.38.23203

Zhao, 1996, The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation, Proc Natl Acad Sci USA, 93, 2454, 10.1073/pnas.93.6.2454

Jungmann, 1993, MAC1, a nuclear regulatory protein related to Cu dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast, EMBO J, 12, 5056, 10.1002/j.1460-2075.1993.tb06198.x

Graden, 1997, Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor, Proc Natl Acad Sci USA, 94, 5550, 10.1073/pnas.94.11.5550

Winge, 1997, Sensors that mediate copper-specific activation and repression of gene expression, J Bioinorg Chem, 2, 2

Casas, 1997, The AFT1 transcription factor is differentially required for expression of high-affinity iron uptake genes in Saccharomyces cerevisiae, Yeast, 13, 621, 10.1002/(SICI)1097-0061(19970615)13:7<621::AID-YEA121>3.0.CO;2-U

Zhao, 1997, Zap1p, a metalloregulatory protein involved in zinc-responsive transcriptional regulation in Saccharomyces cerevisiae, Mol Cell Biol, 17, 5044, 10.1128/MCB.17.9.5044

Furst, 1988, Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein, Cell, 55, 705, 10.1016/0092-8674(88)90229-2

Zhou, 1992, Expression of a yeast metallothionein gene family is activated by a single metalloregulatory transcription factor, Mol Cell Biol, 12, 3766, 10.1128/MCB.12.9.3766

Graden, 1996, Presence of a copper(I)-thiolate regulatory domain in the copper-activated transcription factor Amt1, Biochemistry, 35, 14583, 10.1021/bi961642v

Farrell, 1996, Identification of the Zn(II) site in the copper-responsive yeast transcription factor, ATM1: a conserved Zn module, Biochemistry, 35, 1571, 10.1021/bi9517087

Zhou, 1993, Rapid transcriptional autoregulation of a yeast metalloregulatory transcription factor is essential for high-level copper detoxification, Genes Dev, 7, 1824, 10.1101/gad.7.9.1824

Koch, 1996, Autoactivation by a Candida glabrata copper metalloregulatory transcription factor requires critical minor groove interactions, Mol Cell Biol, 16, 724, 10.1128/MCB.16.2.724

Lin, 1995, The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity, Proc Natl Acad Sci USA, 92, 3784, 10.1073/pnas.92.9.3784

Yuan, 1997, Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway, J Biol Chem, 272, 25787, 10.1074/jbc.272.41.25787

Lin, 1997, A role for the Saccharomyces cerevisiae ATX1 gene is copper trafficking and iron transport, J Biol Chem, 272, 9215, 10.1074/jbc.272.14.9215

Radisky, 1997, Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast, Proc Natl Acad Sci USA, 94, 5662, 10.1073/pnas.94.11.5662

Pufahl, 1997, Metal ion cheperone function of the soluble Cu(I) receptor Atx1, Science, 277, 853, 10.1126/science.278.5339.853

Glerum, 1996, Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase, J Biol Chem, 271, 14504, 10.1074/jbc.271.24.14504

Culotta, 1997, The copper chaperone for superoxide dismutase, J Biol Chem, 272, 23469, 10.1074/jbc.272.38.23469