Metal-coordination synthesis of a natural injectable photoactive hydrogel with antibacterial and blood-aggregating functions for cancer thermotherapy and mild-heating wound repair

Biomaterials Science - Tập 11 Số 7 - Trang 2486-2503
Kiyan Musaie1, Samin Abbaszadeh2, Vahideh Nosrati-Siahmazgi1, Mostafa Qahremani1, Shige Wang3, Mohammad Reza Eskandari4, Seyyed Vahid Niknezhad5, Fakhri Haghi6, Changsheng Liu7, Bo Xiao8, Mohammad‐Ali Shahbazi9,1,10
1Department of Pharmaceutical Biomaterials, School of Pharmacy, Zanjan University of Medical Science, 45139-56184 Zanjan, Iran
2Department of Pharmacology, School of Medicine, Zanjan University of Medical Sciences, 45139-56111 Zanjan, Iran
3School of Materials and Chemistry, the University of Shanghai for Science and Technology, No. 516 Jungong Road, Shanghai 200093, P.R. China
4Department of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Science, 45139-56184 Zanjan, Iran
5Program in Craniofacial Biology, Department of Cell and Tissue Biology, University of California, San Francisco, CA 1, USA
6Department of Microbiology and Immunology, Faculty of Medical Sciences, Zanjan University of Medical Sciences, 45139-56111 Zanjan, Iran
7Key Laboratory for Ultrafine Materials of Ministry of Education, Engineering Research Centre for Biomedical Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
8State Key Laboratory of Silkworm Genome Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing, 400715, China
9Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, Netherlands
10W.J. Kolff Institute for Biomedical Engineering and Materials Science, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, the Netherlands

Tóm tắt

Rapid metal coordination-based formation of a hydrogel is combined with the loading of photoactive nanoparticles and a regenerative drug to establish a multifunctional formulation for cancer therapy and mild-temperature wound healing acceleration.

Từ khóa


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