Metabolic profiling of human blood by high-resolution ion mobility mass spectrometry (IM-MS)

International Journal of Mass Spectrometry - Tập 298 Số 1-3 - Trang 78-90 - 2010
Prabha Dwivedi1, A. Schultz2, Herbert H. Hill3
1Washington State University, Pullman, WA 99163, USA
2Ionwerks Inc., Houston, TX 77005, USA
3Department of Chemistry, Washington State University, Pullman, WA 99164, USA.

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David, 2004

Michal, 1999

Goodacre, 2005, Metabolomics—the way forward, Metabolomics, 1, 1, 10.1007/s11306-005-1111-7

Goodacre, 2004, Metabolomics by numbers: acquiring and understanding global metabolite data, Trends in Biotechnology, 22, 245, 10.1016/j.tibtech.2004.03.007

Thomas, 2001, Metabolomics breaks the silence, Trends in Microbiology, 9, 158, 10.1016/S0966-842X(01)02010-8

Horning, 1971, Metabolic profiles: gas-phase methods for analysis of metabolites, Clinical Chemistry, 17, 802, 10.1093/clinchem/17.8.802

Dunckley, 2005, Discovery and development of biomarkers of neurological disease, Drug Discovery Today, 10, 326, 10.1016/S1359-6446(04)03353-7

Fell, 2001, Beyond genomics, Trends in Genetics, 17, 680, 10.1016/S0168-9525(01)02521-5

Fernie, 2004, Innovation—metabolite profiling: from diagnostics to systems biology, Nature Reviews Molecular Cell Biology, 5, 763, 10.1038/nrm1451

Fiehn, 2002, Metabolomics—the link between genotypes and phenotypes, Plant Molecular Biology, 48, 155, 10.1023/A:1013713905833

Kodo, 1990, Quantitative assay of free and total carnitine using tandem mass spectrometry, Clinica Chimica Acta, 186, 383, 10.1016/0009-8981(90)90324-L

Rashed, 1997, Screening blood spots for inborn errors of metabolism by electrospray tandem mass spectrometry with a microplate batch process and a computer algorithm for automated flagging of abnormal profiles, Clinical Chemistry (Washington, D.C.), 43, 1129, 10.1093/clinchem/43.7.1129

Giovannoni, 1997, Raised serum nitrate and nitrite levels in patients with multiple sclerosis, Journal of the Neurological Sciences, 145, 77, 10.1016/S0022-510X(96)00246-8

Zangerle, 1995, Serum nitrite plus nitrate in infection with human immunodeficiency virus type-1, Immunobiology, 193, 59, 10.1016/S0171-2985(11)80155-5

Kawashima, 2004, Serum and cerebrospinal fluid nitrite/nitrate levels in patients with rotavirus gastroenteritis induced convulsion, Life Sciences, 74, 1397, 10.1016/j.lfs.2003.08.014

Kawashima, 2002, High concentration of serum nitrite/nitrate obtained from patients with influenza-associated encephalopathy, Pediatrics International, 44, 705, 10.1046/j.1442-200X.2002.01650.x

Zarzycki, 2006, Determination of steroids in human plasma using temperature-dependent inclusion chromatography for metabolomic investigations, Journal of Chromatography A, 1104, 203, 10.1016/j.chroma.2005.11.119

Figueroa, 2002, Abnormal lipid concentrations in cystic fibrosis, American Journal of Clinical Nutrition, 75, 1005, 10.1093/ajcn/75.6.1005

Caulfield, 2002, The diagnosis of congenital adrenal hyperplasia in the newborn by gas chromatography/mass spectrometry analysis of random urine specimens, The Journal of Clinical Endocrinology and Metabolism, 87, 3682, 10.1210/jc.87.8.3682

Shackleton, 2004, Biochemical diagnosis of Antley-Bixler syndrome by steroid analysis, American Journal of Medical Genetics Part A, 128A, 223, 10.1002/ajmg.a.30104

Gornati, 1998, Total glycolipid and glucosylceramide content in serum and urine of patients with Gaucher's disease type 3 before and after enzyme replacement therapy, Clinica Chimica Acta, 271, 151, 10.1016/S0009-8981(97)00241-6

Zhang, 2004, Review: glycosphingolipids in health and disease, Annals of Clinical and Laboratory Science, 34, 3

Vance, 1969, Concentrations of glycosyl ceramides in plasma and red cells in Fabry's disease, a glycolipid lipidosis, Journal of Lipid Research, 10, 188, 10.1016/S0022-2275(20)42667-7

Tall, 2001

Mirzoyan, 1978, Blood glycolipids in patients with brain blood-circulation disorders, Zhurnal Nevropatologii i Psikhiatrii imeni S. S. Korsakova, 78, 1317

Atzpodien, 1976, Study of plasma glycosphingolipids in acute hepatitis, Verhandlungen der Deutschen Gesellschaft fuer Innere Medizin, 82, 429, 10.1007/978-3-642-85451-4_98

Markuszewski, 2005, Human red blood cells targeted metabolome analysis of glycolysis cycle metabolites by capillary electrophoresis using an indirect photometric detection method, Journal of Pharmaceutical and Biomedical Analysis, 39, 636, 10.1016/j.jpba.2005.04.015

Dettmer, 2004, Metabolomics—a new exciting field within the “omics” sciences, Environmental Health Perspectives, 112, A396, 10.1289/ehp.112-1241997

Dunn, 2005, Metabolomics: current analytical platforms and methodologies, Trends in Analytical Chemistry, 24, 285, 10.1016/j.trac.2004.11.021

Fiehn, 2001, Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks, Comparative and Functional Genomics, 2, 155, 10.1002/cfg.82

Jiye, 2005, Extraction and GC/MS analysis of the human blood plasma metabolome, Analytical Chemistry, 77, 8086, 10.1021/ac051211v

Hope, 2005, Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry detection: analysis of amino acid and organic acid trimethylsilyl derivatives, with application to the analysis of metabolites in rye grass samples, Talanta, 65, 380, 10.1016/j.talanta.2004.06.025

Katz, 2004, A new technique (COMSPARI) to facilitate the identification of minor compounds in complex mixtures by GC/MS and LC/MS: tools for the visualization of matched datasets, Journal of the American Society for Mass Spectrometry, 15, 580, 10.1016/j.jasms.2003.12.011

Taylor, 2002, Application of metabolomics to plant genotype discrimination using statistics and machine learning, Bioinformatics (Oxford, England), 18, S241, 10.1093/bioinformatics/18.suppl_2.S241

Gamache, 2004, Metabolomic applications of electrochemistry/mass spectrometry, Journal of the American Society for Mass Spectrometry, 15, 1717, 10.1016/j.jasms.2004.08.016

Lu, 2006, A high-performance liquid chromatography–tandem mass spectrometry method for quantitation of nitrogen-containing intracellular metabolites, Journal of the American Society for Mass Spectrometry, 17, 37, 10.1016/j.jasms.2005.09.001

Pham-Tuan, 2003, Method development in high-performance liquid chromatography for high-throughput profiling and metabonomic studies of biofluid samples, Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 789, 283, 10.1016/S1570-0232(03)00077-1

Vigneau-Callahan, 2001, Characterization of diet-dependent metabolic serotypes: analytical and biological variability issues in rats, Journal of Nutrition, 131, 924S, 10.1093/jn/131.3.924S

Wagner, 2006, Metabonomics and biomarker discovery: LC–MS metabolic profiling and constant neutral loss scanning combined with multivariate data analysis for mercapturic acid analysis, Analytical Chemistry, 78, 1296, 10.1021/ac051705s

Wilson Ian, 2005, HPLC–MS-based methods for the study of metabonomics, Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 817, 67, 10.1016/j.jchromb.2004.07.045

Yang, 2006, High performance liquid chromatography–mass spectrometry for metabonomics: potential biomarkers for acute deterioration of liver function in chronic hepatitis B, Journal of Proteome Research, 5, 554, 10.1021/pr050364w

Anon., 2003, Research profile; CE/MS for quantitative metabolome analysis, Journal of Proteome Research, 2, 463, 10.1021/pr0307467

Sato, 2004, Simultaneous determination of the main metabolites in rice leaves using capillary electrophoresis mass spectrometry and capillary electrophoresis diode array detection, Plant Journal, 40, 151, 10.1111/j.1365-313X.2004.02187.x

Soga, 2003, Quantitative metabolome analysis using capillary electrophoresis mass spectrometry, Journal of Proteome Research, 2, 488, 10.1021/pr034020m

Suresh, 2006, Capillary electrophoresis at the omics level: towards systems biology, Electrophoresis, 27, 97, 10.1002/elps.200500511

Chen, 2005, Journal of Chromatography A, 1089, 87, 10.1016/j.chroma.2005.06.067

Lenz, 2003, A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects, Journal of Pharmaceutical and Biomedical Analysis, 33, 1103, 10.1016/S0731-7085(03)00410-2

Bhalla, 2005, Metabolomics and its role in understanding cellular responses in plants, Plant Cell Reports, 24, 562, 10.1007/s00299-005-0054-9

Nicholls, 2001, Metabonomic investigations into hydrazine toxicity in the rat, Chemical Research in Toxicology, 14, 975, 10.1021/tx000231j

Holmes, 2000, Chemometric models for toxicity classification based on NMR spectra of biofluids, Chemical Research in Toxicology, 13, 471, 10.1021/tx990210t

Wu, 2005, NMR spectroscopic-based metabonomic investigation on the acute biochemical effects induced by Ce(NO3)3 in rats, Journal of Inorganic Biochemistry, 99, 2151, 10.1016/j.jinorgbio.2005.07.014

Viant, 2003, NMR-based metabolomics: a powerful approach for characterizing the effects of environmental stressors on organism health, Environmental Science & Technology, 37, 4982, 10.1021/es034281x

Pendyala, 2007, Biomarkers for neuroAIDS: the widening scope of metabolomics, Journal of Neuroimmune Pharmacology, 2, 72, 10.1007/s11481-006-9041-3

Dunn, 2008, Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes, Physical Biology, 5, 11001, 10.1088/1478-3975/5/1/011001

Godin, 2007, Liquid chromatography combined with mass spectrometry for 13C isotopic analysis in life science research, Mass Spectrometry Reviews, 26, 751, 10.1002/mas.20149

Metz, 2007, The future of liquid chromatography–mass spectrometry (LC–MS) in metabolic profiling and metabolomic studies for biomarker discovery, Biomarkers in Medicine, 1, 159, 10.2217/17520363.1.1.159

Witkamp, 2005, Genomics and systems biology—how relevant are the developments to veterinary pharmacology, toxicology and therapeutics?, Journal of Veterinary Pharmacology and Therapeutics, 28, 235, 10.1111/j.1365-2885.2005.00662.x

Ad de Jong, 2008, Foreword: new developments in CE, CIEF and CE for metabolomics, Journal of Chromatography A, 1204, 129, 10.1016/j.chroma.2008.07.051

Barbas, 2008, Capillary electrophoresis as a metabolomic tool in antioxidant therapy studies, Journal of Pharmaceutical and Biomedical Analysis, 47, 388, 10.1016/j.jpba.2008.01.028

Monton, 2007, Metabolome analysis by capillary electrophoresis–mass spectrometry, Journal of Chromatography A, 1168, 237, 10.1016/j.chroma.2007.02.065

Ramautar, 2009, CE–MS in metabolomics, Electrophoresis, 30, 276, 10.1002/elps.200800512

Soga, 2007, Capillary electrophoresis–mass spectrometry for metabolomics, Methods in Molecular Biology, 358, 129, 10.1007/978-1-59745-244-1_8

van der Kooy, 2009, Quality control of herbal material and phytopharmaceuticals with MS and NMR based metabolic fingerprinting, Planta Medica, 75, 763, 10.1055/s-0029-1185450

Queiroz, 2009, Modern approaches in the search for new lead antiparasitic compounds from higher plants, Current Drug Targets, 10, 202, 10.2174/138945009787581113

Powers, 2009, NMR metabolomics and drug discovery, Magnetic Resonance in Chemistry, 47, S2, 10.1002/mrc.2461

Vangala, 2007, Biomarkers, metabonomics, and drug development: can inborn errors of metabolism help in understanding drug toxicity?, The AAPS Journal, 9, E284, 10.1208/aapsj0903031

Orhan, 2007, Analyses of representative biomarkers of exposure and effect by chromatographic, mass spectrometric, and nuclear magnetic resonance techniques: method development and application in life sciences, Journal of Separation Science, 30, 149, 10.1002/jssc.200600322

Sem, 2001, NMR in the acceleration of drug discovery, Current Opinion in Drug Discovery & Development, 4, 479

DeAngelis, 2003, MD, reflects on agency's challenges, priorities, Journal of the American Medical Association, 289, 1492, 10.1001/jama.289.12.1492

Zerhouni, 2003, The NIH roadmap, Science, 302, 10.1126/science.1091867

Valentine, 2006, Toward plasma proteome profiling with ion mobility-mass spectrometry, Journal of Proteome Research, 5, 2977, 10.1021/pr060232i

Fenn, 2009, Characterizing ion mobility-mass spectrometry conformation space for the analysis of complex biological samples, Analytical and Bioanalytical Chemistry, 394, 235, 10.1007/s00216-009-2666-3

Kanu, 2008, Ion mobility-mass spectrometry, Journal of Mass Spectrometry, 43, 1, 10.1002/jms.1383

Hyung, 2009, Gas-phase unfolding and disassembly reveals stability differences in ligand-bound multiprotein complexes, Chemistry & Biology, 16, 382, 10.1016/j.chembiol.2009.02.008

Chan, 2009, Pharmaceutical metabolite profiling using quadrupole/ion mobility spectrometry/time-of-flight mass spectrometry, Rapid Communications in Mass Spectrometry, 23, 384, 10.1002/rcm.3887

Mie, 2008, Terbutaline enantiomer separation and quantification by complexation and field asymmetric ion mobility spectrometry-tandem mass spectrometry, Analytical Chemistry, 80, 4133, 10.1021/ac702262k

Dwivedi, 2008, A rapid analytical method for hair analysis using ambient pressure ion mobility mass spectrometry with electrospray ionization (ESI-IMMS), International Journal for Ion Mobility Spectrometry, 11, 61, 10.1007/s12127-008-0006-5

Eiceman, 1990, Screening of solid commercial pharmaceuticals using ion mobility spectrometry, Analytical Chemistry, 62, 1374, 10.1021/ac00213a005

Borsdorf, 2002, Atmospheric pressure chemical ionization studies of non-polar isomeric hydrocarbons using ion mobility spectrometry and mass spectrometry with different ionization techniques, Journal of American Society for Mass Spectrometry, 13, 1078, 10.1016/S1044-0305(02)00429-4

Zhao, 2009, Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry, Journal of Chromatographic Science, 47, 92, 10.1093/chromsci/47.1.92

Clowers, 2001, Evaluation of sulfonylurea herbicides using high resolution electrospray ionization ion mobility quadrupole mass spectrometry, Field Analytical Chemistry and Technology, 5, 302, 10.1002/fact.10010

Mie, 2008, Analysis of triazines and associated metabolites with electrospray ionization field-asymmetric ion mobility spectrometry/mass spectrometry, Analytical Sciences: The International Journal of the Japan Society for Analytical Chemistry, 24, 973, 10.2116/analsci.24.973

Steiner, 2005, Detection of a chemical warfare agent simulant in various aerosol matrixes by ion mobility time-of-flight mass spectrometry, Analytical Chemistry, 77, 4792, 10.1021/ac050278f

Hill, H.H. Jr., Dwivedi, P., Kanu, A.B., Reduction in false positive responses for explosives detection using ion mobility-mass spectrometry (IMMS). First Indo-US Workshop on Spectroscopy, vol. 14, Laser and Spectroscopy Society of India, B.H.U. Varanasi, India, 2006, pp. 92–103.

Waltman, 2008, Characterization of a distributed plasma ionization source (DPIS) for ion mobility spectrometry and mass spectrometry, Talanta, 77, 249, 10.1016/j.talanta.2008.06.014

Dwivedi, 2007, Metabolic profiling by ion mobility mass spectrometry (IMMS), Metabolomics

Asbury, 2000, Evaluation of ultrahigh resolution ion mobility spectrometry as an analytical separation device in chromatographic terms, Journal of Microcolumn Separations, 12, 172, 10.1002/(SICI)1520-667X(2000)12:3<172::AID-MCS7>3.0.CO;2-W

Wu, 1998, Electrospray ionization high-resolution ion mobility spectrometry–mass spectrometry, Analytical Chemistry, 70, 10, 10.1021/ac980414z

Steiner, 2001, Electrospray ionization with ambient pressure ion mobility separation and mass analysis by orthogonal time-of-flight mass spectrometry, Rapid Communications in Mass Spectrometry, 15, 2221, 10.1002/rcm.495

Revercomb, 1975, Theory of plasma chromatography/gaseous electrophoresis—a review, Analytical Chemistry, 47, 970, 10.1021/ac60357a043

Sud, 2007, LMSD: LIPID MAPS structure database, Nucleic Acids Research, 35, D527, 10.1093/nar/gkl838

Fahy, 2005, A comprehensive classification system for lipids, Journal of Lipid Research, 46, 839, 10.1194/jlr.E400004-JLR200

Smith, 2005, METLIN—a metabolite mass spectral database, Therapeutic Drug Monitoring, 27, 747, 10.1097/01.ftd.0000179845.53213.39

Kopka, 2005, [email protected]: the Golm Metabolome Database, Bioinformatics, 21, 1635, 10.1093/bioinformatics/bti236

Koeniger, 2006, An IMS–IMS analogue of MS–MS, Analytical Chemistry, 78, 4161, 10.1021/ac051060w

Merenbloom, 2006, IMS–IMS and IMS–IMS–IMS/MS for separating peptide and protein fragment ions, Analytical Chemistry, 78, 2802, 10.1021/ac052208e

Valentine, 2009, Developing IMS–IMS–MS for rapid characterization of abundant proteins in human plasma, International Journal of Mass Spectrometry, 283, 149, 10.1016/j.ijms.2009.02.030

Woods, 2004, Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS, Analytical Chemistry, 76, 2187, 10.1021/ac035376k

Clowers, 2005, Separation of sodiated isobaric disaccharides and trisaccharides using electrospray ionization-atmospheric pressure ion mobility-time of flight mass spectrometry, Journal of American Society of Mass Spectrometry, 16, 660, 10.1016/j.jasms.2005.01.010

Dwivedi, 2007, Rapid resolution of carbohydrate isomers by electrospray ionization ambient pressure ion mobility spectrometry-time-of-flight mass spectrometry (ESI-APIMS-TOFMS), Journal of the American Society for Mass Spectrometry, 18, 1163, 10.1016/j.jasms.2007.04.007

Britz-McKibbin, 2003, On-line preconcentration strategies for trace analysis of metabolites by capillary electrophoresis, Journal of Chromatography A, 1000, 917, 10.1016/S0021-9673(03)00502-8

Lidebjer, 2007, Low plasma levels of oxygenated carotenoids in patients with coronary artery disease, Nutrition, Metabolism, and Cardiovascular Diseases, 17, 448, 10.1016/j.numecd.2006.02.006

Kita, 2005, Pathway-oriented profiling of lipid mediators in macrophages, Biochemical and Biophysical Research Communications, 330, 898, 10.1016/j.bbrc.2005.03.055

Serhan, 2005, Mediator lipidomics, Prostaglandins & Other Lipid Mediators, 77, 4, 10.1016/j.prostaglandins.2004.09.016

Jackson, 2005, Direct tissue analysis of phospholipids in rat brain using MALDI-TOFMS and MALDI-ion mobility-TOFMS, Journal of the American Society for Mass Spectrometry, 16, 133, 10.1016/j.jasms.2004.10.002

Ruotolo, 2002, Peak capacity of ion mobility mass spectrometry: separation of peptides in helium buffer gas, Journal of Chromatography B Analytical Technologies in Biomedical and Life Sciences, 782, 385, 10.1016/S1570-0232(02)00566-4

Ruotolo, 2002, Distinguishing between phosphorylated and nonphosphorylated peptides with ion mobility-mass spectrometry, Journal of Proteome Research, 1, 303, 10.1021/pr025516r

Morris, 2005, Focused metabolomic profiling in the drug development process: advances from lipid profiling, Current Opinion in Chemical Biology, 9, 407, 10.1016/j.cbpa.2005.06.002

Ruotolo, 2003, Peak capacity of ion mobility mass spectrometry: separation of peptides in helium buffer gas, Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 782, 8

Frahm, 2006, Accessible proteomics space and its implications for peak capacity for zero-, one- and two-dimensional separations coupled with FT-ICR and TOF mass spectrometry, Journal of Mass Spectrometry, 41, 281, 10.1002/jms.1024

Rose, 1994, Two-dimensional gel electrophoresis/liquid chromatography for the micropreparative isolation of proteins, Analytical Chemistry, 66, 2529, 10.1021/ac00087a018

McLean, 2005, Ion mobility-mass spectrometry: a new paradigm for proteomics, International Journal of Mass Spectrometry, 240, 301, 10.1016/j.ijms.2004.10.003

Liu, 2007, Mapping the human plasma proteome by SCX-LC–IMS-MS, Journal of the American Society for Mass Spectrometry, 18, 1249, 10.1016/j.jasms.2007.04.012

Merenbloom, 2007, Assessing the peak capacity of IMS-IMS separations of tryptic peptide ions in He at 300K, Analytical Chemistry, 79, 515, 10.1021/ac061567m

Want, 2006, Solvent-dependent metabolite distribution. Clustering, and protein extraction for serum profiling with mass spectrometry, Analytical Chemistry, 78, 743, 10.1021/ac051312t

Roy, 2004, Differential expression profiling of serum proteins and metabolites for biomarker discovery, International Journal of Mass Spectrometry, 238, 163, 10.1016/j.ijms.2004.03.017

Nordstrom, 2006, Nonlinear data alignment for UPLC–MS and HPLC–MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum, Analytical Chemistry, 78, 3289, 10.1021/ac060245f