Metabolic engineering of methanotrophs and its application to production of chemicals and biofuels from methane

Biofuels, Bioproducts and Biorefining - Tập 10 Số 6 - Trang 848-863 - 2016
Ok Kyung Lee1, Dong Hoon Hur1, Diep Thi Ngoc Nguyen1, Eun Yeol Lee1
1Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do, 446-701 Korea

Tóm tắt

AbstractMethane‐assimilating bacteria, methanotrophs, can play an important role in producing various value‐added chemicals and biofuels from methane, which is considered a next‐generation carbon feedstock. The capability to engineer the metabolic pathway of methanotrophs is a key success factor for enhancing methane‐to‐product conversion efficiency. Recently, OMICS studies on several model methanotrophs have been conducted and provided strategies to engineer methanotrophs. Here, we present a review on the current progresses and future prospects of metabolic engineering of methanotrophs and its application to chemical and biofuel production from methane. © 2016 Society of Chemical Industry and John Wiley & Sons, Ltd

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