Metabolic Fluxes and Metabolic Engineering
Tóm tắt
Từ khóa
Tài liệu tham khảo
Aiba, 1979, Identification of metabolic model: Citrate production from glucose byCandida lipolytica, Biotechnol. Bioeng., 21, 1373, 10.1002/bit.260210806
Aristidou, 1994, Modification of the central metabolic pathways ofEscherichia coliBacillus subtilis, Biotechnol. Bioeng., 44, 944, 10.1002/bit.260440810
Bailey, 1991, Towards a science of metabolic engineering, Science, 252, 1668, 10.1126/science.2047876
Brabetz, 1991, Studies on the utilization of lactose byCorynebacterium glutamicumEscherichia coli, Arch. Microbiol., 155, 607, 10.1007/BF00245357
Brown, 1990, A ‘top-down' approach to the determination of control coefficients by metabolic control theory, Eur. J. Biochem., 188, 321, 10.1111/j.1432-1033.1990.tb15406.x
Cameron, 1993, Cellular and metabolic engineering, Appl. Biochem. Biotechnol., 38, 105, 10.1007/BF02916416
Chance, 1983, Mathematical analysis of isotope labeling in the citric acid cycle with applications to13, J. Biol. Chem., 258, 13785, 10.1016/S0021-9258(17)43987-1
Chen, 1994, Energetic effect ofVitreoscillaEscherichia coli31, Biotechnol. Progr., 10, 360, 10.1021/bp00028a003
Colón, 1995, Production of isoleucine by overexpression ofilvACorynebacterium lactofermentum, Appl. Microbiol. Biotechnol., 43, 482, 10.1007/BF00218453
Eikmanns, 1991, Amplification of three threonine biosynthetic genes inCorynebacterium glutamicum, Appl. Microbiol. Biotechnol., 34, 617, 10.1007/BF00167910
Fell, 1997
Follstad, 1998, Effect of reversible reactions on isotope label redistribution. Analysis of the pentose phosphate pathway, Eur. J. Biochem., 10.1046/j.1432-1327.1998.2520360.x
Hatzimanikatis, 1996, Analysis and design of metabolic reaction networks via mixed-integer linear optimization, AIChE Journal, 1277, 10.1002/aic.690420509
Heinrich, 1974, A linear steady-state treatment of enzymatic chains. General properties, control and effector strength, Eur. J. Biochem., 42, 39
Ikeda, 1992, Metabolic engineering to produce tyrosine or phenylalanine in a tryptophan-producingCorynebacterium glutamicum, Appl. Environ. Microbiol., 58, 781, 10.1128/AEM.58.3.781-785.1992
Jørgensen, 1995, Metabolic flux distributions inPenicillium chrysogenum, Biotechnol. Bioeng., 46, 117, 10.1002/bit.260460205
Kacser, 1973, The control of flux, Symp. Soc. Exp. Biol., 27, 65
Kao, 1997
Kelleher, 1985, Analysis of tricarboxylic acid using [14, Am. J. Physiol., 248, E252
Kelleher, 1987, Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of142, Biochem. J., 246, 633, 10.1042/bj2460633
Kellogg, 1981, Plasmid-assisted molecular breeding: new technique for enhanced biodegradation of persistent toxic chemicals, Science, 214, 1133, 10.1126/science.7302584
Khosla, 1988, Heterologous Expression of a Bacterial Hemoglobin Improves the Growth Properties of RecombinantEscherichia coli, Nature, 331, 633, 10.1038/331633a0
Klapa, M. I. Park, S. M. Sinskey, A. J. Stephanopoulos, G. 1998, Effect of the tricarboxylic acid cycle on metabolite labeling. I. Theory
Lee, 1994, Photosynthetic water splitting: In situ photoprecipitation of metallocatalysts for photoevolution of hydrogen and oxygen, Energy Fuels : ACS J., 8, 770, 10.1021/ef00045a034
Lee, 1994, Metabolic engineering ofPseudomonas putidap, Biotechnol. Bioeng., 43, 1146, 10.1002/bit.260431120
MacQuitty, 1988, Impact of Biotechnology on the Chemical Industry, ACS Sympos. Ser., 362, 11, 10.1021/bk-1988-0362.ch002
Mancuso, 1994, Examination of primary metabolic pathways in a murine hybridoma with carbon-13 NMR spectroscopy, Biotechnol. Bioeng., 44, 563, 10.1002/bit.260440504
Marx, 1996, Determination of the fluxes in the central metabolism ofC. glutamicum, Biotechnol. Bioeng., 49, 111, 10.1002/(SICI)1097-0290(19960120)49:2<111::AID-BIT1>3.0.CO;2-T
Malloy, 1987, Carbon flux through citric acid cycle pathways in perfused heart by13, FEBS Lett., 212, 58, 10.1016/0014-5793(87)81556-9
Malloy, 1988, Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by13, J. Biol. Chem., 263, 6964, 10.1016/S0021-9258(18)68590-4
Malloy, 1990, Analysis of the tricarboxylic acid cycle of the heart using13, Am. J. Physiol., 259, H987
Nawrath, 1994, Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids ofArabidopsis thaliana, Proc. Nat'l. Acad. Sci. USA, 91, 12760, 10.1073/pnas.91.26.12760
Nissen, 1997, Flux distributions in anaerobic, glucose-limited continuous cultures ofS. cerevisiae, Microbiology, 143, 203, 10.1099/00221287-143-1-203
Nyberg, G. Balcarcel, R. Follstad, B. Stephanopoulos, G. Wang, D. I. C. 1997, Glycosylation site occupancy in continuous culture of Chinese Hamster Ovary cells producing recombinant human gamma interferon, 229b, Los Angeles
Nyberg, 1998
Ohta, 1991, Genetic improvement ofEscherichia coliZymomonas mobilis, Appl. Environ. Microbiol., 57, 893, 10.1128/AEM.57.4.893-900.1991
Ohta, 1991, Metabolic engineering ofKlebsiella oxytoca, Appl. Environ. Microbiol., 57, 2810, 10.1128/AEM.57.10.2810-2815.1991
Papoutsakis, 1984, Equations and calculations for fermenations of butyric acid bacteria, Biotechnol. Bioeng., 26, 1187, 10.1002/bit.260260210
Park, 1997, Metabolic and physiological studies ofCorynebacterium glutamicum, Biotechnol. Bioeng., 55, 864, 10.1002/(SICI)1097-0290(19970920)55:6<864::AID-BIT5>3.0.CO;2-E
Park, 1997, Elucidation of the anaplerotic pathways inCorynebacterium glutamicum13, Appl. Microb. Biotechnol., 47, 864, 10.1007/s002530050952
Park, S. M. Klapa, M. I. Sinskey, A. J. Stephanopoulos, G. 1998, Effect of the tricarboxylic acid cycle on metabolite labeling. II. Applications
Peoples, 1988, Nucleotide sequence and fine structural analysis of theCorynebacterium glutamicum hom-thrB, Molec. Microbiol., 2, 63, 10.1111/j.1365-2958.1988.tb00007.x
Pramanik, 1997, Stoichiometric model ofEscherichia coli, Biotechnol. Bioeng., 50, 398, 10.1002/(SICI)1097-0290(19971120)56:4<398::AID-BIT6>3.0.CO;2-J
Sauer, 1997, Metabolic fluxes in riboflavin-producingBacillus subtillis, Nat. Biotechnol., 15, 448, 10.1038/nbt0597-448
Savageau, 1969, Biochemical Systems Analysis. I. Some mathematical properties of the rate law for the component enzymatic reactions, J. Theor. Biol., 25, 365, 10.1016/S0022-5193(69)80026-3
Savageau, 1969, Biochemical Systems Analysis. II. The steady-state solutions for an n-pool system using a power-law approximation, J. Theor. Biol., 25, 370, 10.1016/S0022-5193(69)80027-5
Savageau, 1970, Biochemical Systems Analysis. III. Dynamic solutions using a power-law approximation, J. Theor. Biol., 26, 215, 10.1016/S0022-5193(70)80013-3
Savageau, 1987, Biochemical systems theory and metabolic control theory: 1. Fundamental similarities and differences, Math. Biosci., 86, 127, 10.1016/0025-5564(87)90007-1
Savageau, 1987, Biochemical systems theory and metabolic control theory: 2. The role of summation and connectivity relationships, Math. Biosci., 86, 147, 10.1016/0025-5564(87)90008-3
Schlosser, 1993, Determining metabolic sensitivity coefficients directly from experimental data, Biotechnol. Bioeng., 41, 1027, 10.1002/bit.260411105
Schmidt, 1997, Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices, Biotechnol. Bioeng., 55, 831, 10.1002/(SICI)1097-0290(19970920)55:6<831::AID-BIT2>3.0.CO;2-H
Schubert, 1988, Cloning of theAlcaligenes eutrophusEscherichia coli, J. Bacteriol., 170, 5837, 10.1128/jb.170.12.5837-5847.1988
Sharfstein, 1994, Quantitative in vivo nuclear magnetic resonance studies of hybridoma metabolism, Biotechnol. Bioeng., 43, 1059, 10.1002/bit.260431109
Shaw-Reid, 1997
Simpson, 1998, Experimental determination of group flux control coefficients in metabolic networks, Biotechnol. Bioeng., 10.1002/(SICI)1097-0290(19980420)58:2/3<149::AID-BIT6>3.0.CO;2-L
Slater, 1988, Cloning and expression inEscherichia coliAlcaligenes eutrophus, J. Bacteriol., 170, 4431, 10.1128/jb.170.10.4431-4436.1988
Sonntag, 1993, Flux partitioning in the split pathway of lysine synthesis inCorynebacterium glutamicum131, Eur. J. Biochem., 213, 1325, 10.1111/j.1432-1033.1993.tb17884.x
Stephanopoulos, 1991, Network rigidity and metabolic engineering in metabolite overproduction, Science, 252, 1675, 10.1126/science.1904627
Stephanopoulos, 1998
Stephanopoulos, 1997, Flux amplification in complex metabolic networks, Chem. Eng. Sci., 52, 2607, 10.1016/S0009-2509(97)00077-8
Szyperski, 1996, Detecting and dissecting metabolic fluxes using biosynthetic fractional 13C labeling and two-dimensional NMR spectroscopy, Trends Biotechnol., 14, 453, 10.1016/S0167-7799(96)10056-1
Takiguchi, 1997, An online physiological-state recognition system for the lysine fermentation process based on a metabolic reaction model, Biotechnol. Bioeng., 55, 170, 10.1002/(SICI)1097-0290(19970705)55:1<170::AID-BIT18>3.0.CO;2-Q
Timmis, 1988, Prospects for laboratory engineering of bacteria to degrade pollutants, Basic Life Sci., 45, 61
Tong, 1991, 1,3-propanediol production byEscherichia coliKlebsiella pneumonia dha, Appl. Environ. Microbiol., 57, 3541, 10.1128/AEM.57.12.3541-3546.1991
Vallino, 1991
Vallino, 1987, Intelligent Sensors in Biotechnology: Applications for the Monitoring of Fermentations and Cellular Metabolism, Ann. NY Acad. Sci., 506, 413, 10.1111/j.1749-6632.1987.tb23838.x
Vallino, 1994, Carbon flux distributions at the glucose 6-phosphate branch point inCorynebacterium glutamicum, Biotechnol. Progr., 10, 327, 10.1021/bp00027a014
Vallino, 1994, Carbon flux distributions at the pyruvate branch point inCorynebacterium glutamicum, Biotechnol. Progr., 10, 320, 10.1021/bp00027a013
van der Heijden, 1994, Linear constraint relations in biochemical reaction systems: I. Classification of the calculability and the balanceability of conversion rates, Biotechnol. Bioeng., 43, 3, 10.1002/bit.260430103
van der Heijden, 1994, Linear constraint relations in biochemical reaction systems: II. Diagnosis and estimation of gross measurement errors, Biotechnol. Bioeng., 43, 11, 10.1002/bit.260430104
Varma, 1993, Stoichiometric interpretation ofEscherichia coli, Appl. Environ. Microbiol., 59, 2465, 10.1128/AEM.59.8.2465-2473.1993
Varma, 1993, Biochemical production capabilities ofEscherichia coli, Biotechnol. Bioeng., 42, 59, 10.1002/bit.260420109
Wang, 1983, Application of macroscopic balances to the identification of gross measurement errors, Biotechnol. Bioeng., 25, 2177, 10.1002/bit.260250906
Wiechert, 1997, Bidirectional reaction steps in metabolic networks: I. modeling and simulation of carbon isotope labeling experiments, Biotechnol. Bioeng., 55, 101, 10.1002/(SICI)1097-0290(19970705)55:1<101::AID-BIT12>3.0.CO;2-P
Wiechert, 1997, Bidirectional reaction steps in metabolic networks: II. flux estimation and statistical analysis, Biotechnol. Bioeng., 55, 118, 10.1002/(SICI)1097-0290(19970705)55:1<118::AID-BIT13>3.0.CO;2-I
Windass, 1980, Improved conversion of methanol to single-cell protein byMethyllophilus methylotrophus, Nature, 287, 396, 10.1038/287396a0
Yarmush, 1997, Metabolic Engineering and Human Disease, Nature Biotechnol., 15, 525, 10.1038/nbt0697-525
Zhang, 1995, Metabolic engineering of a pentose metabolism pathway in ethanologenicZymomonas mobilis, Science, 267, 240, 10.1126/science.267.5195.240
Zupke, 1994, Modeling of isotope distributions and intracellular fluxes in metabolic networks using atom mapping matrices, Biotechnol. Progr., 10, 489, 10.1021/bp00029a006
Zupke, 1995, Intracellular flux analysis in hybridomas using mass balances and in vitro C13 NMR, Biotechnol. Bioeng., 45, 292, 10.1002/bit.260450403
Zupke, 1995, Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas, Appl. Microbiol. Biotechnol., 44, 27, 10.1007/BF00164476