Merits and Liabilities of NSAID Therapy

April, 1987, Multicenter comparative study of salsalate vs aspirin in rheumatoid arthritis, Arthritis Rheum, 30, S93 Baum, 1985, Utilization of nonsteroidal anti-inflammatory drugs, Arthritis Rheum, 28, 686, 10.1002/art.1780280613 Bland, 1983, Absorption of enteric-coated aspirin, JAMA, 249, 59, 10.1001/jama.1983.03330260016012 Bratter, 1988, Clinical pharmacology of NSAIDs, J Clin Pharmacol, 28, 518, 10.1002/j.1552-4604.1988.tb03171.x Brogden, 1979, Flurbiprofen: A review of its pharmacological properties and therapeutic use in rheumatic diseases, Drugs, 18, 417, 10.2165/00003495-197918060-00001 1986, CSM Update: Nonsteroidal anti-inflammatory drugs and serious gastrointestinal adverse reactions—II, Br Med J, 292, 1190, 10.1136/bmj.292.6529.1190 Dromgoole, 1988, Diflunisal, 399 Eberl, 1983, Long-term experience with meclofenamate sodium, Arzeimittelforsch, 33, 667 Ehrlich, 1975, Pseudo-proteinuria in tolmetin-treated patients, Clin Pharmacol Ther, 17, 467, 10.1002/cpt1975174467 Furst, 1987, Pheynlbutazone, 265 Godfrey, 1971, A double-blind crossover trial of aspirin, indomethacin, and phenylbutazone in ankylosing spondylitis, Arthritis Rheum, 15, 110 Goldlust B, Roth SH, Mitchell CS: Reduced risk of nonsteroidal anti-inflammatory (NSAID) gastropathy with nonacetylated salicylate. Presented at the Sixth SEAPAL Congress of Rheumatology, Tokyo, September 7, 1988 Graham, 1988, Prevention of NSAID induced gastric ulcer with misoprostil: Multicenter double-blind placebo-controlled trial, Lancet, 2, 1277, 10.1016/S0140-6736(88)92892-9 Harter JG: FDA Drug Review Perspective. Presented at the 49th Annual ARA Meeting, Anaheim, June 1985 Hutt, 1983, The metabolic chiral inversion of 2-aryl-proprionic acids—A novel route with pharmacologic consequences, J Pharmacol, 35, 694 Lee, 1985, Stereoselective disposition of ibuprofen enantiomers in man, Br J Clin Pharmacol, 19, 669, 10.1111/j.1365-2125.1985.tb02694.x Lubeck, 1986, A multicenter study of annual health service utilization and costs in rheumatoid arthritis, Arthritis Rheum, 29, 614 O’Brien, 1986, Adverse reactions to nonsteroidal anti-inflammatory drugs: diclofenac compared with other nonsteroidal anti-inflammatory drugs, Am J Med, 80, 70, 10.1016/0002-9343(86)90084-7 Roth, 1988, Pharmacologic approaches to musculoskeletal disorders, Clin Geriatr Med, 4, 441, 10.1016/S0749-0690(18)30758-4 Roth, 1988, Salicylates Roth SH: Preliminary gastroscopic comparison of carprofen and ibuprofen in patients with rheumatoid arthritis. Poster presentation at the Ninth PANLAR Congress of Rheumatology. Buenos Aires, November 19, 1986 Roth, 1985, Salicylates Roth, 1988, Salicylates revisited; Are they still the hallmark of anti-inflammatory therapy?, Drugs, 36, 1, 10.2165/00003495-198836010-00001 Roth, 1984, The new look in drugs: Is ‘longer lasting’ better? (editorial), Arch Intern Med, 144, 472, 10.1001/archinte.1984.00350150056017 Roth SH, Agrawal M, Mahowald M, et al: Misoprostol heals gastroduodenal injury in patients with rheumatoid arthritis receiving aspirin. Arch Intern Med (accepted for publication, 1988) Roth, 1987, NSAID Gastropathy: Recognition and response, Arch Intern Med, 147, 2093, 10.1001/archinte.1987.00370120029008 Roth, 1975, An open trial of naproxen in rheumatoid arthritis patients with significant esophageal, gastric, and duodenal lesions, J Clin Pharmacol, 15, 378, 10.1002/j.1552-4604.1975.tb01468.x O’Brien, 1983, Long term efficacy and safety of tolmetin sodium in treatment of geriatric patients with rheumatoid arthritis and osteoarthritis: A retrospective study, J Clinic Pharmacol, 23, 309, 10.1002/j.1552-4604.1983.tb02741.x Opinion Research Corporation survey, 1988; 3M/Riker internal files Proceedings of the 22nd Arthritis Advisory Committee of the U.S. Food and Drug Administration. Federal Registry, 5/16/88 Reidenberg, 1971 Restivo, 1978, Anaphylaxis from tolmetin, JAMA, 240 Roth, 1982, A comparison of benoxyprofen and sulindac in patients with rheumatoid arthritis and osteoarthritis, European J Rheumatologic Inflammation, 5, 258 Roth, 1987, Endoscopy controlled study of the safety of nabumetone compared with naproxen in arthritis therapy, Am J Med, 83, 25, 10.1016/0002-9343(87)90589-4 Roth, 1980, New direction—Which direction?, 117 Roth, 1988, NSAIDs and gastropathy: A rheumatologist’s review, J Rheuma, 15, 912 Roth, 1988, NSAIDS: Risk benefit versus cost benefit, Drug Information J, 22, 477, 10.1177/009286158802200321 Roth, 1988, Nonsteroidal anti-inflammatory drugs: Gastropathy, deaths, and medical practice. (editorial), Ann Intern Med, 109, 353, 10.7326/0003-4819-109-5-353 Rothermich, 1966, An extended study of indomethacin, JAMA, 195, 531, 10.1001/jama.1966.03100070075022 Runkel, 1976, Pharmacokinetics of naproxen overdoses, Clin Pharmacol Ther, 20, 269, 10.1002/cpt1976203269 Russell, 1971, Serum transaminases during salicylate therapy, Br Med J, 2, 428, 10.1136/bmj.2.5759.428 Sachs, 1984, Piroxicam safety profile, Intern Med Specialist, 11 Silvoso, 1979, Incidence of gastric lesions in patients with rheumatic disease on chronic aspirin therapy, Ann Intern Med, 91, 517, 10.7326/0003-4819-91-4-517 Swift, 1978, Antypyrine disposition and liver size in the elderly, Eur J Clin Pharmacol, 14, 149, 10.1007/BF00607447 Vane, 1987, Evolution of nonsteroidal anti-inflammatory drugs and their mechanism of action, Drugs, 33, 18, 10.2165/00003495-198700331-00005 Zautra, 1989, Life stress and lymphocyte alterations among patients with rheumatoid arthritis, Health Psychol, 8, 1, 10.1037/0278-6133.8.1.1 Zimmerman, 1974, Aspirin induced hepatic injury, Ann Intern Med, 80, 103, 10.7326/0003-4819-80-1-103