Membrane organization determines barrier properties of endothelial cells and short-chain sphingolipid-facilitated doxorubicin influx

A.J. van Hell, A. Klymchenko, D.M. Gueth, W.J. van Blitterswijk, G.A. Koning, M. Verheij

Tài liệu tham khảo

Lankelma, 1999, Doxorubicin gradients in human breast cancer, Clin. Cancer Res., 5, 1703 Tredan, 2007, Drug resistance and the solid tumor microenvironment, J. Natl. Cancer Inst., 99, 1441, 10.1093/jnci/djm135 Dobson, 2008, Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?, Nat. Rev. Drug Discov., 7, 205, 10.1038/nrd2438 Sugano, 2010, Coexistence of passive and carrier-mediated processes in drug transport, Nat. Rev. Drug Discov., 9, 597, 10.1038/nrd3187 Aird, 2007, Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms; II. Representative vascular beds, Circ. Res., 100, 158, 10.1161/01.RES.0000255691.76142.4a van Hell, 2013, Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance, Sci. Rep., 3, 1949, 10.1038/srep01949 van Lummel, 2011, Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors, FASEB J., 25, 280, 10.1096/fj.10-163709 Veldman, 2004, N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx, Br. J. Cancer, 90, 917, 10.1038/sj.bjc.6601581 Veldman, 2005, Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin, J. Pharmacol. Exp. Ther., 315, 704, 10.1124/jpet.105.087486 Constantinides, 1990, Transverse location of anthracyclines in lipid bilayers: paramagnetic quenching studies, Biophys. Chem., 35, 259, 10.1016/0301-4622(90)80013-W van Meer, 1986, The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells, EMBO J., 5, 1455, 10.1002/j.1460-2075.1986.tb04382.x van Meer, 1987, Sorting of sphingolipids in epithelial (Madin–Darby canine kidney) cells, J. Cell Biol., 105, 1623, 10.1083/jcb.105.4.1623 van Meer, 1986, The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next, Nature, 322, 639, 10.1038/322639a0 Kucherak, 2010, Switchable Nile red-based probe for cholesterol and lipid order at the outer leaflet of biomembranes, J. Am. Chem. Soc., 132, 4907, 10.1021/ja100351w Sampaio, 2010, Membrane lipidome of an epithelial cell line, Proc. Natl. Acad. Sci. U. S. A., 108, 1903, 10.1073/pnas.1019267108 Lehmann, 2000, Raf induces TGFβ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells, Genes Dev., 14, 2610, 10.1101/gad.181700 Lingwood, 2008, Plasma membranes are poised for activation of raft phase coalescence at physiological temperature, Proc. Natl. Acad. Sci. U. S. A., 105, 10005, 10.1073/pnas.0804374105 Xiang, 1998, Influence of chain ordering on the selectivity of dipalmitoylphosphatidylcholine bilayer membranes for permeant size and shape, Biophys. J., 75, 2658, 10.1016/S0006-3495(98)77711-2 Xiang, 2006, Liposomal drug transport: a molecular perspective from molecular dynamics simulations in lipid bilayers, Adv. Drug Deliv. Rev., 58, 1357, 10.1016/j.addr.2006.09.002 van Meer, 2008, Membrane lipids: where they are and how they behave, Nat. Rev., 9, 112, 10.1038/nrm2330 Muller, 1986, Plasmalemmal proteins of cultured vascular endothelial cells exhibit apical–basal polarity: analysis by surface-selective iodination, J. Cell Biol., 103, 2389, 10.1083/jcb.103.6.2389 Tournier, 1989, The lateral motion of lipid molecules in the apical plasma membrane of endothelial cells is reversibly affected by the presence of cell junctions, Exp. Cell Res., 181, 375, 10.1016/0014-4827(89)90095-5 Lombardi, 1985, Polarized plasma membrane domains in cultured endothelial cells, Exp. Cell Res., 161, 242, 10.1016/0014-4827(85)90508-7 Stoletov, 2010, Visualizing extravasation dynamics of metastatic tumor cells, J. Cell Sci., 123, 2332, 10.1242/jcs.069443 Julien, 1995, Basic fibroblast growth factor modulates the aminophospholipid translocase activity present in the plasma membrane of bovine aortic endothelial cells, Eur. J. Biochem., 230, 287, 10.1111/j.1432-1033.1995.0287i.x