Medical therapy for non-functioning pituitary tumors—a critical approach

Hormones - Tập 18 - Trang 117-126 - 2018
Metaxia Tampourlou1, Olga Karapanou1, Dimitra A. Vassiliadi1, Stylianos Tsagarakis1
1Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece

Tóm tắt

Non-functioning pituitary adenomas (NFPAs) are the second most common variant of pituitary tumors. When symptomatic, primary therapy is surgery. Recurrence rates are high. Since many NFPAs express dopamine and somatostatin receptors, medical therapy has been used after surgery in order to prevent recurrence. So far, dopamine agonists have been more widely tested with some promise when introduced immediately after surgery but with less efficacy when introduced later upon tumor regrowth. Currently, the role of medical therapy to prevent tumor regrowth in NFPAs is limited by imprecisions as to final outcome and uncertainties concerning on patient selection, dosing, duration, and side effects.

Tài liệu tham khảo

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