Mechanisms impairing blood pressure responses to nitrite and nitrate
Tài liệu tham khảo
Pagidipati, 2013, Estimating deaths from cardiovascular disease: a review of global methodologies of mortality measurement, Circulation, 127, 749, 10.1161/CIRCULATIONAHA.112.128413
Perk, 2012, Eur. Heart J., 33, 1635, 10.1093/eurheartj/ehs092
Li, 2015, Mechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertension, J. Hypertens., 33, 1128, 10.1097/HJH.0000000000000587
Lim, 2012, A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010, Lancet, 380, 2224, 10.1016/S0140-6736(12)61766-8
Kearney, 2005, Global burden of hypertension: analysis of worldwide data, Lancet, 365, 217, 10.1016/S0140-6736(05)17741-1
Chobanian, 2009, Shattuck Lecture. The hypertension paradox--more uncontrolled disease despite improved therapy, N. Engl. J. Med., 361, 878, 10.1056/NEJMsa0903829
Coffman, 2011, Under pressure: the search for the essential mechanisms of hypertension, Nat. Med., 17, 1402, 10.1038/nm.2541
Oliveira-Paula, 2013, Inducible nitric oxide synthase haplotype associated with hypertension and responsiveness to antihypertensive drug therapy, Gene, 515, 391, 10.1016/j.gene.2012.12.059
Beevers, 2001, ABC of hypertension: the pathophysiology of hypertension, BMJ, 322, 912, 10.1136/bmj.322.7291.912
Bian, 2008, Vascular system: role of nitric oxide in cardiovascular diseases, J. Clin. Hypertens., 10, 304, 10.1111/j.1751-7176.2008.06632.x
Oliveira-Paula, 2016, Endothelial nitric oxide synthase: from biochemistry and gene structure to clinical implications of NOS3 polymorphisms, Gene, 575, 584, 10.1016/j.gene.2015.09.061
Villanueva, 2010, Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease, Free Radic. Biol. Med., 49, 307, 10.1016/j.freeradbiomed.2010.04.004
Lundberg, 2008, The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics, Nat. Rev. Drug Discov., 7, 156, 10.1038/nrd2466
Machha, 2011, Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits, Eur. J. Nutr., 50, 293, 10.1007/s00394-011-0192-5
Kim-Shapiro, 2014, Mechanisms of nitrite bioactivation, Nitric Oxide, 38, 58, 10.1016/j.niox.2013.11.002
Rocha, 2011, Dietary nitrite in nitric oxide biology: a redox interplay with implications for pathophysiology and therapeutics, Curr. Drug Targets, 12, 1351, 10.2174/138945011796150334
Alderton, 2001, Nitric oxide synthases: structure, function and inhibition, Biochem. J., 357, 593, 10.1042/bj3570593
Cortese-Krott, 2014, Endothelial nitric oxide synthase in red blood cells: key to a new erythrocrine function?, Redox Biol, 2, 251, 10.1016/j.redox.2013.12.027
Oliveira-Paula, 2014, Inducible nitric oxide synthase as a possible target in hypertension, Curr. Drug Targets, 15, 164, 10.2174/13894501113146660227
Walford, 2003, Nitric oxide in vascular biology, J. Thromb. Haemostasis, 1, 2112, 10.1046/j.1538-7836.2003.00345.x
Francis, 2010, cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action, Pharmacol. Rev., 62, 525, 10.1124/pr.110.002907
Wilcox, 2005, Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension?, Am. J. Physiol. Regul. Integr. Comp. Physiol., 289, R913, 10.1152/ajpregu.00250.2005
Baylis, 1994, Acute nitric oxide blockade amplifies the renal vasoconstrictor actions of angiotension II, J. Am. Soc. Nephrol., 5, 211, 10.1681/ASN.V52211
Sartori, 2005, Interaction between nitric oxide and the cholinergic and sympathetic nervous system in cardiovascular control in humans, Pharmacol. Ther., 106, 209, 10.1016/j.pharmthera.2004.11.009
Pinheiro, 2016, Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect, Free Radic. Biol. Med., 101, 226, 10.1016/j.freeradbiomed.2016.10.013
Daaka, 2012, S-nitrosylation-regulated GPCR signaling, Biochim. Biophys. Acta, 1820, 743, 10.1016/j.bbagen.2011.03.007
Leclerc, 2006, S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II, Br. J. Pharmacol., 148, 306, 10.1038/sj.bjp.0706725
Ozawa, 2008, S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking, Mol. Cell., 31, 395, 10.1016/j.molcel.2008.05.024
Albrecht, 2003, Protective role of endothelial nitric oxide synthase, J. Pathol., 199, 8, 10.1002/path.1250
Moreno, 1996, Chronic nitric oxide inhibition as a model of hypertensive heart muscle disease, Basic Res. Cardiol., 91, 248, 10.1007/BF00788911
Li, 2002, Physiological mechanisms regulating the expression of endothelial-type NO synthase, Nitric Oxide, 7, 132, 10.1016/S1089-8603(02)00127-1
Pinheiro, 2017, The potential of stimulating nitric oxide formation in the treatment of hypertension, Expert Opin. Ther. Targets, 21, 543, 10.1080/14728222.2017.1310840
Linz, 1999, Interactions among ACE, kinins and NO, Cardiovasc. Res., 43, 549, 10.1016/S0008-6363(99)00091-7
Mentz, 2013, The past, present and future of renin-angiotensin aldosterone system inhibition, Int. J. Cardiol., 167, 1677, 10.1016/j.ijcard.2012.10.007
Silva, 2013, eNOS and BDKRB2 genotypes affect the antihypertensive responses to enalapril, Eur. J. Clin. Pharmacol., 69, 167, 10.1007/s00228-012-1326-2
Oliveira-Paula, 2017, Gene-Gene interactions among PRKCA, NOS3 and BDKRB2 polymorphisms affect the antihypertensive effects of enalapril, Basic Clin. Pharmacol. Toxicol., 120, 284, 10.1111/bcpt.12682
Oliveira-Paula, 2016, Endothelial nitric oxide synthase tagSNPs influence the effects of enalapril in essential hypertension, Nitric Oxide, 55–56, 62, 10.1016/j.niox.2016.03.006
Oliveira-Paula, 2015, Polymorphisms in VEGFA gene affect the antihypertensive responses to enalapril, Eur. J. Clin. Pharmacol., 71, 949, 10.1007/s00228-015-1872-5
Cosentino, 2005, Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists, Am. J. Hypertens., 18, 493, 10.1016/j.amjhyper.2004.11.007
Liao, 2005, Pleiotropic effects of statins, Annu. Rev. Pharmacol. Toxicol., 45, 89, 10.1146/annurev.pharmtox.45.120403.095748
Laufs, 1998, Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase, J. Biol. Chem., 273, 24266, 10.1074/jbc.273.37.24266
Forstermann, 2010, Nitric oxide and oxidative stress in vascular disease, Pflügers Archiv, 459, 923, 10.1007/s00424-010-0808-2
Oliveira-Paula, 2017, Clinical and pharmacogenetic impact of endothelial nitric oxide synthase polymorphisms on cardiovascular diseases, Nitric Oxide, 63, 39, 10.1016/j.niox.2016.08.004
Dejam, 2005, Erythrocytes are the major intravascular storage sites of nitrite in human blood, Blood, 106, 734, 10.1182/blood-2005-02-0567
Shiva, 2006, Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis, Nat. Chem. Biol., 2, 486, 10.1038/nchembio813
McKnight, 1997, Chemical synthesis of nitric oxide in the stomach from dietary nitrate in humans, Gut, 40, 211, 10.1136/gut.40.2.211
van Velzen, 2008, The oral bioavailability of nitrate from nitrate-rich vegetables in humans, Toxicol. Lett., 181, 177, 10.1016/j.toxlet.2008.07.019
Kapil, 2014, Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health, Nitric Oxide, 38, 45, 10.1016/j.niox.2014.03.162
Benjamin, 1994, Stomach NO synthesis, Nature, 368, 502, 10.1038/368502a0
Lundberg, 1994, Intragastric nitric oxide production in humans: measurements in expelled air, Gut, 35, 1543, 10.1136/gut.35.11.1543
Castiglione, 2012, Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease, Antioxidants Redox Signal., 17, 684, 10.1089/ars.2011.4196
Gladwin, 2008, The functional nitrite reductase activity of the heme-globins, Blood, 112, 2636, 10.1182/blood-2008-01-115261
Omar, 2014, Nitrite reduction and cardiovascular protection, J. Mol. Cell. Cardiol., 73, 57, 10.1016/j.yjmcc.2014.01.012
Cosby, 2003, Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation, Nat. Med., 9, 1498, 10.1038/nm954
Jia, 1996, S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control, Nature, 380, 221, 10.1038/380221a0
Angelo, 2006, An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate, Proc. Natl. Acad. Sci. U. S. A., 103, 8366, 10.1073/pnas.0600942103
Shiva, 2007, Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration, Circ. Res., 100, 654, 10.1161/01.RES.0000260171.52224.6b
Hendgen-Cotta, 2008, Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury, Proc. Natl. Acad. Sci. U. S. A., 105, 10256, 10.1073/pnas.0801336105
Totzeck, 2012, Nitrite regulates hypoxic vasodilation via myoglobin-dependent nitric oxide generation, Circulation, 126, 325, 10.1161/CIRCULATIONAHA.111.087155
Battelli, 2014, Pathophysiology of circulating xanthine oxidoreductase: new emerging roles for a multi-tasking enzyme, Biochim. Biophys. Acta, 1842, 1502, 10.1016/j.bbadis.2014.05.022
Cantu-Medellin, 2013, Xanthine oxidoreductase-catalyzed reactive species generation: a process in critical need of reevaluation, Redox Biol, 1, 353, 10.1016/j.redox.2013.05.002
Suzuki, 1998, Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats, Proc. Natl. Acad. Sci. U. S. A., 95, 4754, 10.1073/pnas.95.8.4754
Swei, 1999, A mechanism of oxygen free radical production in the Dahl hypertensive rat, Microcirculation, 6, 179, 10.1111/j.1549-8719.1999.tb00100.x
Landmesser, 2007, Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease, Arterioscler. Thromb. Vasc. Biol., 27, 943, 10.1161/01.ATV.0000258415.32883.bf
Cantu-Medellin, 2013, Xanthine oxidoreductase-catalyzed reduction of nitrite to nitric oxide: insights regarding where, when and how, Nitric Oxide, 34, 19, 10.1016/j.niox.2013.02.081
Maia, 2015, Nitrite reductase activity of rat and human xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: evaluation of their contribution to NO formation in vivo, Biochemistry, 54, 685, 10.1021/bi500987w
Li, 2008, Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase, J. Biol. Chem., 283, 17855, 10.1074/jbc.M801785200
Zweier, 2010, Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall, Nitric Oxide, 22, 83, 10.1016/j.niox.2009.12.004
Kelley, 2015, A new paradigm for XOR-catalyzed reactive species generation in the endothelium, Pharmacol. Rep., 67, 669, 10.1016/j.pharep.2015.05.004
Millar, 1998, Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions, FEBS Lett., 427, 225, 10.1016/S0014-5793(98)00430-X
Damacena-Angelis, 2017, Nitrate decreases xanthine oxidoreductase-mediated nitrite reductase activity and attenuates vascular and blood pressure responses to nitrite, Redox Biol, 12, 291, 10.1016/j.redox.2017.03.003
Godber, 2000, Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase, J. Biol. Chem., 275, 7757, 10.1074/jbc.275.11.7757
Zhang, 1998, Generation of nitric oxide by a nitrite reductase activity of xanthine oxidase: a potential pathway for nitric oxide formation in the absence of nitric oxide synthase activity, Biochem. Biophys. Res. Commun., 249, 767, 10.1006/bbrc.1998.9226
Maia, 2011, Nitrite reduction by xanthine oxidase family enzymes: a new class of nitrite reductases, J. Biol. Inorg. Chem., 16, 443, 10.1007/s00775-010-0741-z
Montenegro, 2014, Vascular xanthine oxidoreductase contributes to the antihypertensive effects of sodium nitrite in L-NAME hypertension, Naunyn-Schmiedeberg’s Arch. Pharmacol., 387, 591, 10.1007/s00210-014-0970-8
Oliveira-Paula, 2016, Tempol improves xanthine oxidoreductase-mediated vascular responses to nitrite in experimental renovascular hypertension, Redox Biol, 8, 398, 10.1016/j.redox.2016.04.001
Ghosh, 2013, Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential, Hypertension, 61, 1091, 10.1161/HYPERTENSIONAHA.111.00933
Khambata, 2015, "Repurposing" of xanthine oxidoreductase as a nitrite reductase: a new paradigm for therapeutic targeting in hypertension, Antioxidants Redox Signal., 23, 340, 10.1089/ars.2015.6254
Dias-Junior, 2006, Low-dose intravenous nitrite improves hemodynamics in a canine model of acute pulmonary thromboembolism, Free Radic. Biol. Med., 41, 1764, 10.1016/j.freeradbiomed.2006.08.022
Zuckerbraun, 2010, Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation, Circulation, 121, 98, 10.1161/CIRCULATIONAHA.109.891077
Baliga, 2012, Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase, Circulation, 125, 2922, 10.1161/CIRCULATIONAHA.112.100586
Webb, 2004, Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage, Proc. Natl. Acad. Sci. U. S. A., 101, 13683, 10.1073/pnas.0402927101
Li, 2009, Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite, J. Biol. Chem., 284, 33850, 10.1074/jbc.M109.019125
Pinder, 2009, Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways, Br. J. Pharmacol., 157, 1523, 10.1111/j.1476-5381.2009.00340.x
Larsen, 2011, Dietary inorganic nitrate improves mitochondrial efficiency in humans, Cell Metabol., 13, 149, 10.1016/j.cmet.2011.01.004
Shiva, 2010, Mitochondria as metabolizers and targets of nitrite, Nitric Oxide, 22, 64, 10.1016/j.niox.2009.09.002
Kevil, 2011, Inorganic nitrite therapy: historical perspective and future directions, Free Radic. Biol. Med., 51, 576, 10.1016/j.freeradbiomed.2011.04.042
Castello, 2006, Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes, Cell Metabol., 3, 277, 10.1016/j.cmet.2006.02.011
Ascenzi, 2016, The nitrite reductase activity of horse heart carboxymethylated-cytochrome c is modulated by cardiolipin, J. Biol. Inorg. Chem., 21, 421, 10.1007/s00775-016-1351-1
Ascenzi, 2014, Cardiolipin modulates allosterically the nitrite reductase activity of horse heart cytochrome c, J. Biol. Inorg. Chem., 19, 1195, 10.1007/s00775-014-1175-9
Belikova, 2006, Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes, Biochemistry, 45, 4998, 10.1021/bi0525573
Kozlov, 1999, Nitrite reductase activity is a novel function of mammalian mitochondria, FEBS Lett., 454, 127, 10.1016/S0014-5793(99)00788-7
Classen, 1990, Hypothesis: the effect of oral nitrite on blood pressure in the spontaneously hypertensive rat. Does dietary nitrate mitigate hypertension after conversion to nitrite?, J. Am. Coll. Nutr., 9, 500, 10.1080/07315724.1990.10720407
Beier, 1995, Antihypertensive effect of oral nitrite uptake in the spontaneously hypertensive rat, Arzneimittelforschung, 45, 258
Haas, 1999, Persistent antihypertensive effect of oral nitrite supplied up to one year via the drinking water in spontaneously hypertensive rats, Arzneimittelforschung, 49, 318
Tsuchiya, 2005, Nitrite is an alternative source of NO in vivo, Am. J. Physiol. Heart Circ. Physiol., 288, H2163, 10.1152/ajpheart.00525.2004
Montenegro, 2012, Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension, Naunyn-Schmiedeberg’s Arch. Pharmacol., 385, 509, 10.1007/s00210-011-0712-0
Montenegro, 2011, Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension, Free Radic. Biol. Med., 51, 144, 10.1016/j.freeradbiomed.2011.04.005
Pinheiro, 2014, The antihypertensive effects of sodium nitrite are not associated with circulating angiotensin converting enzyme inhibition, Nitric Oxide, 40, 52, 10.1016/j.niox.2014.05.009
Amaral, 2015, Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension, Redox Biol, 5, 340, 10.1016/j.redox.2015.06.009
Montenegro, 2017, Blood pressure-lowering effect of orally ingested nitrite is abolished by a proton pump inhibitor, Hypertension, 69, 23, 10.1161/HYPERTENSIONAHA.116.08081
Chien, 2014, Two different approaches to restore renal nitric oxide and prevent hypertension in young spontaneously hypertensive rats: l-citrulline and nitrate, Transl. Res., 163, 43, 10.1016/j.trsl.2013.09.008
Pinheiro, 2015, Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension, Free Radic. Biol. Med., 87, 252, 10.1016/j.freeradbiomed.2015.06.038
Jansson, 2008, A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis, Nat. Chem. Biol., 4, 411, 10.1038/nchembio.92
Larsen, 2006, Effects of dietary nitrate on blood pressure in healthy volunteers, N. Engl. J. Med., 355, 2792, 10.1056/NEJMc062800
Sobko, 2010, Dietary nitrate in Japanese traditional foods lowers diastolic blood pressure in healthy volunteers, Nitric Oxide, 22, 136, 10.1016/j.niox.2009.10.007
Webb, 2008, Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite, Hypertension, 51, 784, 10.1161/HYPERTENSIONAHA.107.103523
Larsen, 2007, Effects of dietary nitrate on oxygen cost during exercise, Acta Physiol., 191, 59, 10.1111/j.1748-1716.2007.01713.x
Kapil, 2015, Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study, Hypertension, 65, 320, 10.1161/HYPERTENSIONAHA.114.04675
Dejam, 2007, Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation, Circulation, 116, 1821, 10.1161/CIRCULATIONAHA.107.712133
Sindler, 2011, Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging, Aging Cell, 10, 429, 10.1111/j.1474-9726.2011.00679.x
Gao, 2015, NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite, Hypertension, 65, 161, 10.1161/HYPERTENSIONAHA.114.04222
Carlstrom, 2011, Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension, Cardiovasc. Res., 89, 574, 10.1093/cvr/cvq366
Montezano, 2015, Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies, Can. J. Cardiol., 31, 631, 10.1016/j.cjca.2015.02.008
Guimaraes, 2018, Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy, Free Radic. Biol. Med., 120, 25, 10.1016/j.freeradbiomed.2018.03.006
Rizzi, 2019, Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects, Free Radic. Biol. Med., 130, 234, 10.1016/j.freeradbiomed.2018.11.002
Peleli, 2016, Enhanced XOR activity in eNOS-deficient mice: effects on the nitrate-nitrite-NO pathway and ROS homeostasis, Free Radic. Biol. Med., 99, 472, 10.1016/j.freeradbiomed.2016.09.004
Lundberg, 2013, Biology of nitrogen oxides in the gastrointestinal tract, Gut, 62, 616, 10.1136/gutjnl-2011-301649
Oliveira-Paula, 2019, Nitrite-stimulated gastric formation of S-nitrosothiols as an antihypertensive therapeutic strategy, Curr. Drug Targets, 20, 431, 10.2174/1389450119666180816120816
Edwards, 1954, Antagonism between perchlorate, iodide, thiocyanate, and nitrate for secretion in human saliva; analogy with the iodide trap of the thyroid, Lancet, 266, 498, 10.1016/S0140-6736(54)91196-4
Bailey, 2016, Improvement in blood pressure after short-term inorganic nitrate supplementation is attenuated in cigarette smokers compared to non-smoking controls, Nitric Oxide, 61, 29, 10.1016/j.niox.2016.10.002
Dewhurst-Trigg, 2018, Lowering of blood pressure after nitrate-rich vegetable consumption is abolished with the co-ingestion of thiocyanate-rich vegetables in healthy normotensive males, Nitric Oxide, 74, 39, 10.1016/j.niox.2018.01.009
Olea, 1992, Determination of serum levels of dietary thiocyanate, J. Anal. Toxicol., 16, 258, 10.1093/jat/16.4.258
Angelino, 2015, Myrosinase-dependent and -independent formation and control of isothiocyanate products of glucosinolate hydrolysis, Front. Plant Sci., 6, 831, 10.3389/fpls.2015.00831
Verkerk, 2009, Glucosinolates in Brassica vegetables: the influence of the food supply chain on intake, bioavailability and human health, Mol. Nutr. Food Res., 53, S219, 10.1002/mnfr.200800065
Knight, 1987, Estimation of dietary intake of nitrate and nitrite in Great Britain, Food Chem. Toxicol., 25, 277, 10.1016/0278-6915(87)90123-2
Ladd, 1984, N-nitrosation of proline in smokers and nonsmokers, J. Natl. Cancer Inst., 73, 83
Ahmed, 2017, Measuring nitrate reductase activity from human and rodent tongues, Nitric Oxide, 66, 62, 10.1016/j.niox.2017.04.001
Petersson, 2009, Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash, Free Radic. Biol. Med., 46, 1068, 10.1016/j.freeradbiomed.2009.01.011
Shapiro, 1991, Quantitative relationship between oral nitrate-reducing activity and the endogenous formation of N-nitrosoamino acids in humans, Food Chem. Toxicol., 29, 751, 10.1016/0278-6915(91)90183-8
Bondonno, 2015, Antibacterial mouthwash blunts oral nitrate reduction and increases blood pressure in treated hypertensive men and women, Am. J. Hypertens., 28, 572, 10.1093/ajh/hpu192
Govoni, 2008, The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash, Nitric Oxide, 19, 333, 10.1016/j.niox.2008.08.003
Kapil, 2013, Physiological role for nitrate-reducing oral bacteria in blood pressure control, Free Radic. Biol. Med., 55, 93, 10.1016/j.freeradbiomed.2012.11.013
McDonagh, 2015, The effects of chronic nitrate supplementation and the use of strong and weak antibacterial agents on plasma nitrite concentration and exercise blood pressure, Int. J. Sports Med., 36, 1177, 10.1055/s-0035-1554700
Woessner, 2016, A stepwise reduction in plasma and salivary nitrite with increasing strengths of mouthwash following a dietary nitrate load, Nitric Oxide, 54, 1, 10.1016/j.niox.2016.01.002
Hezel, 2015, The oral microbiome and nitric oxide homoeostasis, Oral Dis., 21, 7, 10.1111/odi.12157
Duncan, 1995, Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate, Nat. Med., 1, 546, 10.1038/nm0695-546
Doel, 2005, Evaluation of bacterial nitrate reduction in the human oral cavity, Eur. J. Oral Sci., 113, 14, 10.1111/j.1600-0722.2004.00184.x
Lundberg, 2004, Nitrate, bacteria and human health, Nat. Rev. Microbiol., 2, 593, 10.1038/nrmicro929
Lundberg, 2004, Inorganic nitrate is a possible source for systemic generation of nitric oxide, Free Radic. Biol. Med., 37, 395, 10.1016/j.freeradbiomed.2004.04.027
Zetterquist, 1999, Salivary contribution to exhaled nitric oxide, Eur. Respir. J., 13, 327, 10.1034/j.1399-3003.1999.13b18.x
Katz, 2010, Failing the acid test: benefits of proton pump inhibitors may not justify the risks for many users, Arch. Intern. Med., 170, 747, 10.1001/archinternmed.2010.64
Shi, 2008, Proton pump inhibitors: an update of their clinical use and pharmacokinetics, Eur. J. Clin. Pharmacol., 64, 935, 10.1007/s00228-008-0538-y
Pinheiro, 2012, Increase in gastric pH reduces hypotensive effect of oral sodium nitrite in rats, Free Radic. Biol. Med., 53, 701, 10.1016/j.freeradbiomed.2012.06.001
Kobayashi, 2018, Effect of diet and gut environment on the gastrointestinal formation of N-nitroso compounds: a review, Nitric Oxide, 73, 66, 10.1016/j.niox.2017.06.001
Shah, 2015, Proton pump inhibitor usage and the risk of myocardial infarction in the general population, PLoS One, 10, 10.1371/journal.pone.0124653
Bateman, 2003, Mortality study of 18 000 patients treated with omeprazole, Gut, 52, 942, 10.1136/gut.52.7.942
Ghebremariam, 2013, Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine, Circulation, 128, 845, 10.1161/CIRCULATIONAHA.113.003602
Pinheiro, 2016, Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction, Redox Biol, 9, 134, 10.1016/j.redox.2016.08.001
Sobala, 1989, Ascorbic acid in the human stomach, Gastroenterology, 97, 357, 10.1016/0016-5085(89)90071-1
Stsiapura, 2018, S-Nitrosoglutathione formation at gastric pH is augmented by ascorbic acid and by the antioxidant vitamin complex, Resiston, Pharm. Biol., 56, 86, 10.1080/13880209.2017.1421674
Pinheiro, 2018, Contrasting effects of low versus high ascorbate doses on blood pressure responses to oral nitrite in L-NAME-induced hypertension, Nitric Oxide, 74, 65, 10.1016/j.niox.2018.01.006
Amaral, 2013, TEMPOL enhances the antihypertensive effects of sodium nitrite by mechanisms facilitating nitrite-derived gastric nitric oxide formation, Free Radic. Biol. Med., 65, 446, 10.1016/j.freeradbiomed.2013.07.032
Rocha, 2009, Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation, Toxicology, 265, 41, 10.1016/j.tox.2009.09.008
Peri, 2005, Apples increase nitric oxide production by human saliva at the acidic pH of the stomach: a new biological function for polyphenols with a catechol group?, Free Radic. Biol. Med., 39, 668, 10.1016/j.freeradbiomed.2005.04.021
Gago, 2007, Red wine-dependent reduction of nitrite to nitric oxide in the stomach, Free Radic. Biol. Med., 43, 1233, 10.1016/j.freeradbiomed.2007.06.007
McDonagh, 2018
Kashiba-Iwatsuki, 1996, Role of ascorbic acid in the metabolism of S-nitroso-glutathione, FEBS Lett., 389, 149, 10.1016/0014-5793(96)00560-1
Smith, 2000, Kinetics and mechanism of the decomposition of S-nitrosoglutathione by l-ascorbic acid and copper ions in aqueous solution to produce nitric oxide, Nitric Oxide, 4, 57, 10.1006/niox.2000.0272
Pascart, 2017, Current and future therapies for gout, Expert Opin. Pharmacother., 18, 1201, 10.1080/14656566.2017.1351945
Carvalho, 2017, Impaired xanthine oxidoreductase (XOR)-mediated nitrite reductase activity possibly involved in the lack of antihypertensive effects of XOR inhibitors, Hypertens. Res., 40, 301, 10.1038/hr.2016.138
Kramkowski, 2016, Role of xanthine oxidoreductase in the anti-thrombotic effects of nitrite in rats in vivo, Platelets, 27, 245, 10.3109/09537104.2015.1083545
Berry, 2004, Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications, J. Physiol., 555, 589, 10.1113/jphysiol.2003.055913
Pacher, 2006, Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol, Pharmacol. Rev., 58, 87, 10.1124/pr.58.1.6
Kelley, 2015, Dispelling dogma and misconceptions regarding the most pharmacologically targetable source of reactive species in inflammatory disease, xanthine oxidoreductase, Arch. Toxicol., 89, 1193, 10.1007/s00204-015-1523-8
Okamoto, 2003, An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition, J. Biol. Chem., 278, 1848, 10.1074/jbc.M208307200