Mechanisms contributing to intracellular pH homeostasis in an immortalised human chondrocyte cell line

Aickin, 1988, Movement of acid equivalents across the mammalian smooth muscle cell membrane, 3 Bjelle, 1975, Content and composition of glycosaminoglycans in human knee joint cartilage. Variation with site and age in adults, Connect. Tissue Res., 3, 141, 10.3109/03008207509152172 Browning, 1999, Modulation of Na+×H+ exchange by hydrostatic pressure in isolated bovine articular chondrocytes, Acta Physiol. Scand., 166, 39, 10.1046/j.1365-201x.1999.00534.x Burckhardt, 2002, The Na+/H+ exchanger gene family, J. Nephrol., 15, S3 Counillon, 1993, Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties, Mol. Pharmacol., 44, 1041 Dascalu, 1993, The control of intracellular pH in cultured avian chondrocytes, J. Physiol., 461, 583, 10.1113/jphysiol.1993.sp019530 Goldring, 1994, Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes, J. Clin. Invest., 94, 2307, 10.1172/JCI117595 Goyal, 2003, Renal expression of novel Na+/H+ exchanger isoform NHE8, Am. J. Physiol., 284, F467 Lagadic-Gossmann, 1992, Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte, J. Physiol., 458, 361, 10.1113/jphysiol.1992.sp019422 Loh, 1996, Effect of Hoe 694, a novel Na+–H+ exchange inhibitor, on intracellular pH regulation in the guinea-pig ventricular myocyte, Br. J. Pharmacol., 118, 1905, 10.1111/j.1476-5381.1996.tb15623.x Marcus, 1973, The effect of low oxygen concentration on growth, glycolysis and sulfate incorporation by articular chondrocytes in monolayer culture, Arthritis Rheum., 16, 646, 10.1002/art.1780160509 Maroudas, 1979, Physicochemical properties of articular cartilage, 215 Moulton, 1997, Detection of protein and mRNA of various components of the NADPH oxidase complex in an immortalized human chondrocyte line, Br. J. Rheumatol., 36, 522, 10.1093/rheumatology/36.5.522 Numata, 2001, Molecular cloning and characterization of a novel (Na+, K+)/H+ exchanger localized to the trans-Golgi network, J. Biol. Chem., 276, 17387, 10.1074/jbc.M101319200 O'Neill, 2002, Differential mechanisms of intracellular pH (pHi) recovery following acid load to in situ bovine articular chondrocytes within different cartilage zones, J. Physiol., Part P, 544, 108P Otte, 1991, Basic cell metabolism of articular cartilage. Manometric studies, Z. Rheumatol., 50, 304 Razaq, 2000, Regulation of intracellular pH by bovine intervertebral disc cells, Cell. Physiol. Biochem., 10, 109, 10.1159/000016340 Sandy, 1999, Chondrocyte-mediated catabolism of aggrecan: evidence for a glycosylphosphatidylinositol-linked protein in the aggrecanase response to interleukin-1 or retinoic acid, Arch. Biochem. Biophys., 367, 258, 10.1006/abbi.1999.1234 Slowman, 1986, Composition and glycosaminoglycan metabolism of articular cartilage from habitually and habitually unloaded sites, Arthritis Rheum., 29, 88, 10.1002/art.1780290112 Stockwell, 1991, Cartilage failure in osteoarthritis: relevance of normal structure and function. A review, Clin. Anat., 4, 161, 10.1002/ca.980040303 Swietach, 2002, Functional and molecular determination of carbonic anhydrase levels in bovine and cultured human chondrocytes, Comp. Biochem. Physiol., 133, 427, 10.1016/S1096-4959(02)00184-7 Tattersall, 2003, Molecular and functional identification of the Na+/H+ exchange isoforms NHE1 and NHE3 in isolated bovine articular chondrocytes, Cell. Physiol. Biochem., 13, 215, 10.1159/000072424 Thomas, 1979, Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ, Biochemistry, 18, 2210, 10.1021/bi00578a012 Thomas, 1984, Experimental displacement of intracellular pH and the mechanism of its subsequent recovery, J. Physiol., 354, 3P, 10.1113/jphysiol.1984.sp015397 Urban, 1994, The chondrocyte: a cell under pressure, Br. J. Rheumatol., 33, 901, 10.1093/rheumatology/33.10.901 Wilkins, 1992, Measurement of intracellular pH in isolated bovine articular chondrocytes, Exp. Physiol., 77, 521, 10.1113/expphysiol.1992.sp003615 Wilkins, 1993, Bovine articular chondrocytes demonstrate only minimal bicarbonate-dependent recovery from changes to intracellular pH, J. Physiol., Part P, 459, 289P Wilkins, 1995, Control of matrix synthesis in isolated bovine chondrocytes by extracellular and intracellular pH, J. Cell. Physiol., 164, 474, 10.1002/jcp.1041640305 Yamazaki, 2000, Modulation of Na+×H+ exchange by osmotic shock in isolated bovine articular chondrocytes, Acta Physiol. Scand., 169, 221, 10.1046/j.1365-201x.2000.00737.x