Mechanism of the Endothelium-Dependent Vasodilation and the Antihypertensive Effect of Brazilian Red wine

Journal of Cardiovascular Pharmacology - Tập 44 Số 3 - Trang 302-309 - 2004
Roberto Soares de Moura1, Daniel Zamith‐Miranda, Ana Cláudia A Pinto, Raquel F Sicca, Maria das Graças Coelho de Souza, L M S Rubenich, Laı́s de Carvalho, B. Rangel, Tania Tano, Socorro Vanesca Frota Gaban, Ângela Castro Resende
1Department of Pharmacology, State University of Rio de Janeiro, Rio de Janeiro, Brazil. [email protected]

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1979, Leger AS, Cochrane AL, Moore F. Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine., Lancet, 1, 1017

Demrow, 1995, Administration of wine and grape juice inhibits in vivo platelet activity and thrombosis in stenosed canine coronary arteries., Circulation, 91, 1182, 10.1161/01.CIR.91.4.1182

Frankel, 1993, Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine., Lancet, 341, 454, 10.1016/0140-6736(93)90206-V

Corder, 2001, Endothelin-1 synthesis reduced by red wine., Nature, 414, 863, 10.1038/414863a

Wallerath, 2003, Red wine increases the expression of human endothelial nitric oxide synthase., J Am Coll Cardiol, 41, 471, 10.1016/S0735-1097(02)02826-7

Flech, 1998, Effects of red a white wine on endothelium-dependent vasorelaxation of rat aorta and human coronary arteries., Am J Physiol, 275, H1183

Fitzpatrick, 1993, Endothelium-dependent vasorelaxating activity of wine and other grape products., Am J Physiol, 265, H774

Soares de Moura, 2002, Antihypertensive, vasodilator and antioxidant effects of a vinifera grape skin extract., J Pharm Pharmacol, 54, 1515, 10.1211/002235702153

Rending, 2001, Effects of red wine, alcohol, and quercetin on coronary resistance and conductance arteries., J Cardiovasc Pharmacol, 38, 219, 10.1097/00005344-200108000-00007

Ribeiro, 1992, Chronic inhibition of nitric oxide synthesis a new model of arterial hypertension., Hypertension, 20, 298, 10.1161/01.HYP.20.3.298

Singleton, 1965, Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents., Am J Enot Vitic, 16, 144, 10.5344/ajev.1965.16.3.144

McGregor, 1965, The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat., J Physiol, 177, 21, 10.1113/jphysiol.1965.sp007572

Stoclet, 1999, Endothelial NO release caused by red wine polyphenols., J Physiol Pharmacol, 50, 535

Andriambeloson, 1999, Mechanism of endothelial nitric oxide-dependent vasorelaxation induced by wine polyphenols in rat thoracic aorta., J Cardiovasc Pharmacol, 33, 248, 10.1097/00005344-199902000-00011

Vanhoutte, 1996, Vascular endothelium: vasoactive mediators., Prog Cardiovasc Dis, 39, 229, 10.1016/S0033-0620(96)80003-X

Waldman, 1987, Cyclic GMP synthesis and function., Pharmacol Rev, 39, 163

Tare, 1990, Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from endothelium., Nature, 346, 69, 10.1038/346069a0

Ndiaye, 2003, Red wine polyphenols cause endothelium-dependent EDHF-mediated relaxations in porcine coronary arteries via a redox-sensitive mechanism., Biochem Biophys Res Commun, 310, 371, 10.1016/j.bbrc.2003.09.028

Corriu, 1996, Endothelium-derived factors and hyperpolarization of the carotid artery of the guinea-pig., Br J Pharmacol, 119, 959, 10.1111/j.1476-5381.1996.tb15765.x

Diebolt, 2001, Wine polyphenols decrease blood pressure, improve NO vasodilatation, and induce gene expression., Hypertension, 38, 159, 10.1161/01.HYP.38.2.159

Bernatova, 2002, Wine phenols improve cardiovascular remodeling and vascular function in NO-deficient hypertension., Am J Physiol Heart Circ Physiol, 282, H942, 10.1152/ajpheart.00724.2001

Soares de Moura, 2001, Anti-hypertensive effect of alcoholic fractions of Vitis vinifera and Vitis labrusca grape skins (abstract)., Fund Clin Pharmacol, 15, 91

Usui, 1999, Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats., Hypertension, 34, 546, 10.1161/01.HYP.34.4.546

de Carvalho, 1990, Comparison of the effect of endothelin on microvessels and macrovessels on Goldblatt II and deoxycorticosterone acetate-salt hypertensive rats., Hypertension, 15, I68, 10.1161/01.HYP.15.2_Suppl.I68

Gardiner, 1990, Control of regional blood flow by endothelium-derived nitric oxide., Hypertension, 15, 486, 10.1161/01.HYP.15.5.486

Navarro, 1994, Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats., Am J Physiol, 267, R1516

Sakuma, 1992, NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic tone?, Circulation Res, 70, 607, 10.1161/01.RES.70.3.607

Cunha, 1993, Evidence that autonomic nervous system plays a major role in the L-NAME-induced hypertension in conscious rats., Am J Hypertension, 6, 806, 10.1093/ajh/6.9.806

Richard, 1995, In vivo evidence of an endothelin-induced vasopressor tone after inhibition of nitric oxide synthesis in rats., Circulation, 91, 771, 10.1161/01.CIR.91.3.771

Naruse, 2000, Augmented expression in tissue endothelin-1 messenger RNA is a common feature in hypertensive rats., J Cardiovasc Pharmacol, 36, S195, 10.1097/00005344-200036001-00059

Bauersachs, 1996, Nitric oxide attenuates the release of endothelium-derived hyperpolarization factor., Circulation, 94, 3341, 10.1161/01.CIR.94.12.3341