Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR
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Adams, 2002, New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications, J. Am. Chem. Soc., 124, 6063, 10.1021/ja017687n
Alford, 2015, An integrated framework advancing membrane protein modeling and design, PLoS Comput. Biol., 11, e1004398, 10.1371/journal.pcbi.1004398
Arkhipov, 2013, Architecture and membrane interactions of the EGF receptor, Cell, 152, 557, 10.1016/j.cell.2012.12.030
Barth, 2007, Toward high-resolution prediction and design of transmembrane helical protein structures, Proc. Natl. Acad. Sci. USA, 104, 15682, 10.1073/pnas.0702515104
Bocharov, 2008, Spatial structure and pH-dependent conformational diversity of dimeric transmembrane domain of the receptor tyrosine kinase EphA1, J. Biol. Chem., 283, 29385, 10.1074/jbc.M803089200
Bocharov, 2008, Spatial structure of the dimeric transmembrane domain of the growth factor receptor ErbB2 presumably corresponding to the receptor active state, J. Biol. Chem., 283, 6950, 10.1074/jbc.M709202200
Bocharov, 2010, Left-handed dimer of EphA2 transmembrane domain: helix packing diversity among receptor tyrosine kinases, Biophys. J., 98, 881, 10.1016/j.bpj.2009.11.008
Bocharov, 2013, Structure of FGFR3 transmembrane domain dimer: implications for signaling and human pathologies, Structure, 21, 2087, 10.1016/j.str.2013.08.026
Bocharov, 2017, The conformation of the epidermal growth factor receptor transmembrane domain dimer dynamically adapts to the local membrane environment, Biochemistry, 56, 1697, 10.1021/acs.biochem.6b01085
Bragin, 2016, HER2 transmembrane domain dimerization coupled with self-association of membrane-embedded cytoplasmic juxtamembrane regions, J. Mol. Biol., 428, 52, 10.1016/j.jmb.2015.11.007
Brewer, 2009, The juxtamembrane region of the EGF receptor functions as an activation domain, Mol. Cell, 34, 641, 10.1016/j.molcel.2009.04.034
Bugge, 2016, Understanding single-pass transmembrane receptor signaling from a structural viewpoint—what are we missing?, FEBS J., 283, 4424, 10.1111/febs.13793
Call, 2010, The structural basis for intramembrane assembly of an activating immunoreceptor complex, Nat. Immunol., 11, 1023, 10.1038/ni.1943
Carpenter, 1979, Epidermal growth factor, Annu. Rev. Biochem., 48, 193, 10.1146/annurev.bi.48.070179.001205
Chen, 2014, Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site, Nat. Commun., 5
Doerner, 2015, Growth factor identity is encoded by discrete coiled-coil rotamers in the EGFR juxtamembrane region, Chem. Biol., 22, 776, 10.1016/j.chembiol.2015.05.008
Ebner, 1991, Epidermal growth factor and transforming growth factor-alpha: differential intracellular routing and processing of ligand-receptor complexes, Cell Regul., 2, 599, 10.1091/mbc.2.8.599
Endres, 2013, Conformational coupling across the plasma membrane in activation of the EGF receptor, Cell, 152, 543, 10.1016/j.cell.2012.12.032
Ferguson, 2003, EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization, Mol. Cell, 11, 507, 10.1016/S1097-2765(03)00047-9
Freed, 2017, EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics, Cell, 171, 1, 10.1016/j.cell.2017.09.017
Garrett, 2002, Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α, Cell, 110, 763, 10.1016/S0092-8674(02)00940-6
Gray, 2003, Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations, J. Mol. Biol., 331, 281, 10.1016/S0022-2836(03)00670-3
Guo, 2013, The adaptor protein-1 mu 1B subunit expands the repertoire of basolateral sorting signal recognition in epithelial cells, Dev. Cell, 27, 353, 10.1016/j.devcel.2013.10.006
Hake, 2008, Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor, Biochemistry, 47, 3096, 10.1021/bi701549a
Heukers, 2013, Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif, J. Cell Sci., 126, 4900, 10.1242/jcs.128611
Hunter, 1984, Protein kinase-C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma-membrane, Nature, 311, 480, 10.1038/311480a0
Hynes, 2016, ErbB2: from an EGFR relative to a central target for cancer therapy, Cancer Res., 76, 3659, 10.1158/0008-5472.CAN-16-1356
Jennings, 2009, 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro, J. Lipid Res., 50, 233, 10.1194/jlr.M800270-JLR200
Jura, 2009, Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment, Cell, 137, 1293, 10.1016/j.cell.2009.04.025
Kahsai, 2011, Multiple ligand-specific conformations of the beta(2)-adrenergic receptor, Nat. Chem. Biol., 7, 692, 10.1038/nchembio.634
Kovacs, 2015, A structural perspective on the regulation of the epidermal growth factor receptor, Annu. Rev. Biochem., 84, 739, 10.1146/annurev-biochem-060614-034402
Kovalenko, 2004, Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking, Biochem. J., 377, 407, 10.1042/bj20031037
Lau, 2009, The structure of the integrin alpha IIb beta 3 transmembrane complex explains integrin transmembrane signalling, EMBO J., 28, 1351, 10.1038/emboj.2009.63
Lemmon, 1994, A dimerization motif for transmembrane [alpha]-helices, Nat. Struct. Mol. Biol., 1, 157, 10.1038/nsb0394-157
Lemmon, 2014, The EGFR family: not so prototypical receptor tyrosine kinases, Cold Spring Harb. Perspect. Biol., 6, 1, 10.1101/cshperspect.a020768
Li, 2006, Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies, Biochemistry, 45, 6241, 10.1021/bi060609y
Lin, 2001, Nuclear localization of EGF receptor and its potential new role as a transcription factor, Nat. Cell Biol., 3, 802, 10.1038/ncb0901-802
Liu, 2007, Investigation of the dimerization of proteins from the epidermal growth factor receptor family by single wavelength fluorescence cross-correlation spectroscopy, Biophys. J., 93, 684, 10.1529/biophysj.106.102087
Liu, 2012, A single ligand is sufficient to activate EGFR dimers, Proc. Natl. Acad. Sci. USA, 109, 10861, 10.1073/pnas.1201114109
Lomize, 2017, Proteome-wide modeling of transmembrane alpha-helical homodimers by TMDOCK, Biophys. J., 112, 358a, 10.1016/j.bpj.2016.11.1941
Lowder, 2015, Structural differences between wild-type and double mutant EGFR modulated by third-generation kinase inhibitors, J. Am. Chem. Soc., 137, 6456, 10.1021/jacs.5b02326
Lu, 2010, Structural evidence for loose linkage between ligand binding and kinase activation in epidermal growth factor receptor, Mol. Cell. Biol., 30, 5432, 10.1128/MCB.00742-10
Luedtke, 2007, Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH, Nat. Chem. Biol., 3, 779, 10.1038/nchembio.2007.49
MacKenzie, 1997, A transmembrane helix dimer: structure and implications, Science, 276, 131, 10.1126/science.276.5309.131
Martín-Nieto, 1998, The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site, Biochemistry, 37, 227, 10.1021/bi971765v
Mi, 2008, Functional and structural stability of the epidermal growth factor receptor in detergent micelles and phospholipid nanodiscs, Biochemistry, 47, 10314, 10.1021/bi801006s
Mi, 2011, Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor, Nat. Struct. Mol. Biol., 18, 984, 10.1038/nsmb.2092
Mineev, 2010, Spatial structure of the transmembrane domain heterodimer of ErbB1 and ErbB2 receptor tyrosine kinases, J. Mol. Biol., 400, 231, 10.1016/j.jmb.2010.05.016
Mineev, 2011, Dimeric structure of the transmembrane domain of glycophorin a in lipidic and detergent environments, Acta Naturae, 3, 90, 10.32607/20758251-2011-3-2-90-98
Mineev, 2014, Toll-like receptor 3 transmembrane domain is able to perform various homotypic interactions: an NMR structural study, FEBS Lett., 588, 3802, 10.1016/j.febslet.2014.08.031
Mineev, 2015, The membrane mimetic affects the spatial structure and mobility of EGFR transmembrane and juxtamembrane domains, Biochemistry, 54, 6295, 10.1021/acs.biochem.5b00851
Morrison, 1993, Role of threonine residues in regulation of the epidermal growth-factor receptor by protein-kinase-C and mitogen-activated protein-kinase, J. Biol. Chem., 268, 15536, 10.1016/S0021-9258(18)82290-6
Muhle-Goll, 2012, Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) beta transmembrane segment, J. Biol. Chem., 287, 26178, 10.1074/jbc.M111.325555
Nadezhdin, 2012, Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment, FEBS Lett., 586, 1687, 10.1016/j.febslet.2012.04.062
Ogiso, 2002, Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains, Cell, 110, 775, 10.1016/S0092-8674(02)00963-7
Poppleton, 2000, The juxtamembrane region of the epidermal growth factor receptor is required for phosphorylation of G alpha(s), Arch. Biochem. Biophys., 383, 309, 10.1006/abbi.2000.2095
Roepstorff, 2009, Differential effects of EGFR ligands on endocytic sorting of the receptor, Traffic, 10, 1115, 10.1111/j.1600-0854.2009.00943.x
Russ, 2000, The GxxxG motif: a framework for transmembrane helix-helix association, J. Mol. Biol., 296, 911, 10.1006/jmbi.1999.3489
Sarabipour, 2016, Mechanism of FGF receptor dimerization and activation, Nat. Commun., 7, 10262, 10.1038/ncomms10262
Scheck, 2011, Surveying protein structure and function using bis-arsenical small molecules, Acc. Chem. Res., 44, 654, 10.1021/ar2001028
Scheck, 2012, Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation, ACS Chem. Biol., 7, 1367, 10.1021/cb300216f
Schneider, 2012, NIH Image to ImageJ: 25 years of image analysis, Nat. Methods, 9, 671, 10.1038/nmeth.2089
Senes, 2004, Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs, Curr. Opin. Struct. Biol., 14, 465, 10.1016/j.sbi.2004.07.007
Slamon, 1987, Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene, Science, 235, 177, 10.1126/science.3798106
Takishima, 1988, Thapsigargin, a novel promoter, phosphorylates the epidermal growth-factor receptor at threonine-669, Biochem. Biophys. Res. Commun., 157, 740, 10.1016/S0006-291X(88)80312-7
Thomas, 2011, Structural linkage between ligand discrimination and receptor activation by type I interferons, Cell, 146, 621, 10.1016/j.cell.2011.06.048
Viklund, 2008, OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar, Bioinformatics, 24, 1662, 10.1093/bioinformatics/btn221
Walker, 2016, Rotamer-Restricted fluorogenicity of the bis-arsenical ReAsH, J. Am. Chem. Soc., 138, 7143, 10.1021/jacs.6b03422
Webb, 2000, Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids, J. Biol. Chem., 275, 261, 10.1074/jbc.275.1.261
Wilson, 2009, Functional selectivity of EGF family peptide growth factors: implications for cancer, Pharmacol. Ther., 122, 1, 10.1016/j.pharmthera.2008.11.008
Wilson, 2012, EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling, Growth Factors, 30, 107, 10.3109/08977194.2011.649918
Winograd-Katz, 2006, Cisplatin induces PKB/Akt activation and p38(MAPK) phosphorylation of the EGF receptor, Oncogene, 25, 7381, 10.1038/sj.onc.1209737
Xia, 2002, Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways, Oncogene, 21, 6255, 10.1038/sj.onc.1205794
Yarden, 2001, Untangling the ErbB signalling network, Nat. Rev. Mol. Cell Biol., 2, 127, 10.1038/35052073
Yarov-Yarovoy, 2006, Multipass membrane protein structure prediction using Rosetta, Proteins, 62, 1010, 10.1002/prot.20817
Zhang, 2006, An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor, Cell, 125, 1137, 10.1016/j.cell.2006.05.013