Measuring blood cholesterol outside the pathology laboratory: issues of accuracy and reliability

Australian and New Zealand Journal of Public Health - Tập 15 - Trang 142-146 - 1991
C.M. Reid1, G.L. Jennings1, R.F. Leonard2, R.A.J. Conyers2
1Alfred and Baker Medical Unit, Alfred Hospital, Melbourne
2Department of Biochemistry, Alfred Hospital, Melbourne

Tóm tắt

Abstract: Desk‐top analysers that are simple to use, portable and free from technical requirements are now widely used for blood cholesterol measurement outside the traditional pathology laboratory setting. Test accuracy and reliability are essential if these portable desk‐top analysers are to be of value in the assessment and management of elevated blood cholesterol.To determine their accuracy and reliability we compared the results obtained from four different desk‐top analysers with those from a teaching hospital's routine laboratory method. The desk‐top analysers assessed were the Ames Minilab, the Kodak DT60, the Boehringer Reflotron and the Abbott Vision.The precision of each desk‐top analyser was within acceptable limits, defined as a coefficient of variation less than 5 per cent. The results from the Vision, Reflotron and DT60 related closely to those from the routine laboratory method, with least squares linear regression slopes ranging from 0.92 to 1.06 and intra‐class correlation coefficients from 0.95 to 0.99.The Minilab showed least agreement with the routine laboratory method and caution should be taken in the interpretation of cholesterol estimations made with this device.

Tài liệu tham khảo

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Australian and New Zealand Journal of Public Health

Tập 15

142-146

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