Measurement of absolute bone blood flow by positron emission tomography
Tóm tắt
A method of measuring bone blood flow has been developed using 18F sodium fluoride and positron emission tomography. The blood flow levels are in line with those obtained experimentally from microsphere embolisation. This investigative method could be applied to elucidate a number of clinical questions involving bone perfusion.
Tài liệu tham khảo
Bordier PhJ, Tun Chot S (1972) Quantitative histology of metabolic bone disease. Clin Endocrinol Metab 1:197
Bunger C, Harving S, Bunger EH (1983) Relationship between intraosseous pressures and intraarticular pressure in arthritis of the knee. Acta Orthop Scand 54:188
Cumming JD (1962) A study of blood flow through bone marrow by a method of venous effluent collection. J Physiol (Lond) 162:13
Garnett ES, Bown BM, Coates G, Nahmias C (1975) An analysis of factors which influence the local accumulation of bone seeking radiopharmaceuticals. Invest Radiol 10:564
Gross PM, Marcus ML, Heistad DD (1981) A measurement of bone blood flow to bone and marrow in experimental animals by means of microsphere technique. J Bone Joint Surg [Am] 63:1028
Lucht U, Buenger C, Krebs B, Hjermind J, Buelow J (1983) Blood flow in the juvenile hip in relation to changes in intraarticular pressure—an experimental investigation in dogs. Acta Orthop Scand 54:182–187
Macpherson A, Shaw NE (1961) Circulation of bone. Lancet 1:1285
Morris MA, Kelly PJ (1980) Use of tracer microspheres to measure bone blood flow in conscious dogs. Calcif Tissue Int 32:69
Nahmias C, Firnau G, Garnett ES (1984) Performance characteristics of the McMaster positron emission tomograph. IEEE NS 31:637
Phelps ME, Huang SC, Hoffman EJ (1979) Tomographic measurements of local cerebral glucose metabolic rates in humans with (F-18)-2-fluoro-2-deoxy-D-glucose: validation of method. Ann Neurol 6:371
Report of the task group on reference man (1975) Publication No 23. International Commission on Radiological Protection. Pergamon Press, p 68
Shinn SS (1968) Physiology of blood circulation in knee. J Bone Joint Surg [Am] 50:812
Van-Dyke D, Anger HO, Yano Y, Bozzini C (1965) Bone blood flow shown with 18F and the positron camera. Am J Physiol 209:67
Wootten R (1974) The single passage extraction 18F in rabbit bone. Clin Sci 47:73