Mature neutrophils and a NF-κB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19

Cell Reports Medicine - Tập 3 - Trang 100652 - 2022
Amit Frishberg1,2,3, Emma Kooistra4,5, Melanie Nuesch-Germano6, Tal Pecht6, Neta Milman3, Nico Reusch6, Stefanie Warnat-Herresthal1,6, Niklas Bruse4,5, Kristian Händler7, Heidi Theis7, Michael Kraut7, Esther van Rijssen8, Bram van Cranenbroek8, Hans JPM. Koenen8, Hidde Heesakkers4, Mark van den Boogaard4, Marieke Zegers4, Peter Pickkers4,5, Matthias Becker7, Anna C. Aschenbrenner1,6,9,7
1Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany
2Institute of Computational Biology, Helmholtz Center Munich, 85764, Neuherberg, Germany
3Department of Immunology, Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel
4Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
5Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands
6Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany
7Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), PRECISE Platform for Genomics and Epigenomics at DZNE and University of Bonn, Bonn, Germany
8Laboratory for Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, Netherlands
9Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands

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Cell Reports Medicine

Tập 3

100652

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