Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Atsawasuwan, 2008, Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity, J. Biol. Chem., 283, 34229, 10.1074/jbc.M803142200

Bierie, 2006, Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer, Nat. Rev. Cancer, 6, 506, 10.1038/nrc1926

Bierie, 2009, Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer, J. Clin. Invest., 119, 1571, 10.1172/JCI37480

Bondareva, 2009, The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells, PLoS ONE, 4, e5620, 10.1371/journal.pone.0005620

Butcher, 2009, A tense situation: forcing tumour progression, Nat. Rev. Cancer, 9, 108, 10.1038/nrc2544

Cabodi, 2006, p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis, Cancer Res., 66, 4672, 10.1158/0008-5472.CAN-05-2909

Colpaert, 2003, The presence of a fibrotic focus in invasive breast carcinoma correlates with the expression of carbonic anhydrase IX and is a marker of hypoxia and poor prognosis, Breast Cancer Res. Treat., 81, 137, 10.1023/A:1025702330207

Coussens, 1999, Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis, Genes Dev., 13, 1382, 10.1101/gad.13.11.1382

Coussens, 2002, Matrix metalloproteinase inhibitors and cancer: trials and tribulations, Science, 295, 2387, 10.1126/science.1067100

Csiszar, 2001, Lysyl oxidases: a novel multifunctional amine oxidase family, Prog. Nucleic Acid Res. Mol. Biol., 70, 1, 10.1016/S0079-6603(01)70012-8

Decitre, 1998, Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas, Lab. Invest., 78, 143

Erler, 2006, Lysyl oxidase mediates hypoxic control of metastasis, Cancer Res., 66, 10238, 10.1158/0008-5472.CAN-06-3197

Erler, 2009, Three-dimensional context regulation of metastasis, Clin. Exp. Metastasis, 26, 35, 10.1007/s10585-008-9209-8

Erler, 2006, Lysyl oxidase is essential for hypoxia-induced metastasis, Nature, 440, 1222, 10.1038/nature04695

Erler, 2009, Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche, Cancer Cell, 15, 35, 10.1016/j.ccr.2008.11.012

Georges, 2007, Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis, Am. J. Physiol. Gastrointest. Liver Physiol., 293, G1147, 10.1152/ajpgi.00032.2007

Girton, 1999, Exploiting glycation to stiffen and strengthen tissue equivalents for tissue engineering, J. Biomed. Mater. Res., 46, 87, 10.1002/(SICI)1097-4636(199907)46:1<87::AID-JBM10>3.0.CO;2-K

Hasebe, 1997, Fibrotic focus in invasive ductal carcinoma of the breast: a histopathological prognostic parameter for tumor recurrence and tumor death within three years after the initial operation, Jpn. J. Cancer Res., 88, 590, 10.1111/j.1349-7006.1997.tb00423.x

Hu, 2008, Regulation of in situ to invasive breast carcinoma transition, Cancer Cell, 13, 394, 10.1016/j.ccr.2008.03.007

Jodele, 2006, Modifying the soil to affect the seed: role of stromal-derived matrix metalloproteinases in cancer progression, Cancer Metastasis Rev., 25, 35, 10.1007/s10555-006-7887-8

Johnson, 2007, Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis, Methods Cell Biol., 83, 547, 10.1016/S0091-679X(07)83023-8

Kagan, 2003, Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell, J. Cell. Biochem., 88, 660, 10.1002/jcb.10413

Katz, 2007, A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration, Nat. Cell Biol., 9, 961, 10.1038/ncb1622

Kim, 1999, The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis, Exp. Cell Res., 253, 78, 10.1006/excr.1999.4706

Kirschmann, 2002, A molecular role for lysyl oxidase in breast cancer invasion, Cancer Res., 62, 4478

Kolacna, 2007, Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix, Physiol. Res., 56, S51, 10.33549/physiolres.931302

Koukoulis, 1993, Distribution of tenascin, cellular fibronectins and integrins in the normal, hyperplastic and neoplastic breast, J. Submicrosc. Cytol. Pathol., 25, 285

Kuperwasser, 2004, Reconstruction of functionally normal and malignant human breast tissues in mice, Proc. Natl. Acad. Sci. USA, 101, 4966, 10.1073/pnas.0401064101

Lahlou, 2007, Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression, Proc. Natl. Acad. Sci. USA, 104, 20302, 10.1073/pnas.0710091104

Lo, 2000, Cell movement is guided by the rigidity of the substrate, Biophys. J., 79, 144, 10.1016/S0006-3495(00)76279-5

Lucero, 2006, Lysyl oxidase: an oxidative enzyme and effector of cell function, Cell. Mol. Life Sci., 63, 2304, 10.1007/s00018-006-6149-9

Madan, 2006, Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma, Hum. Pathol., 37, 9, 10.1016/j.humpath.2005.09.024

Martin, 2008, Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence, Breast Cancer Res., 10, 201, 10.1186/bcr1831

Martin, 2008, Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background, Cancer Res., 68, 6251, 10.1158/0008-5472.CAN-08-0537

Miranti, 2002, Sensing the environment: a historical perspective on integrin signal transduction, Nat. Cell Biol., 4, E83, 10.1038/ncb0402-e83

Mitra, 2006, Integrin-regulated FAK-Src signaling in normal and cancer cells, Curr. Opin. Cell Biol., 18, 516, 10.1016/j.ceb.2006.08.011

Muthuswamy, 2001, ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini, Nat. Cell Biol., 3, 785, 10.1038/ncb0901-785

Oleggini, 2007, Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects, Matrix Biol., 26, 494, 10.1016/j.matbio.2007.02.003

Page-McCaw, 2007, Matrix metalloproteinases and the regulation of tissue remodelling, Nat. Rev. Mol. Cell Biol., 8, 221, 10.1038/nrm2125

Paszek, 2005, Tensional homeostasis and the malignant phenotype, Cancer Cell, 8, 241, 10.1016/j.ccr.2005.08.010

Payne, 2007, Paradoxical roles for lysyl oxidases in cancer–a prospect, J. Cell. Biochem., 101, 1338, 10.1002/jcb.21371

Pfeiffer, 2005, Alpha 2(I) collagen deficient oim mice have altered biomechanical integrity, collagen content, and collagen crosslinking of their thoracic aorta, Matrix Biol., 24, 451, 10.1016/j.matbio.2005.07.001

Postovit, 2008, Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration, J. Cell. Biochem., 103, 1369, 10.1002/jcb.21517

Ramaswamy, 2003, A molecular signature of metastasis in primary solid tumors, Nat. Genet., 33, 49, 10.1038/ng1060

Sawada, 2006, Force sensing by mechanical extension of the Src family kinase substrate p130Cas, Cell, 127, 1015, 10.1016/j.cell.2006.09.044

Sinkus, 2000, High-resolution tensor MR elastography for breast tumour detection, Phys. Med. Biol., 45, 1649, 10.1088/0031-9155/45/6/317

Sternlicht, 1999, The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis, Cell, 98, 137, 10.1016/S0092-8674(00)81009-0

Szauter, 2005, Lysyl oxidase in development, aging and pathologies of the skin, Pathol. Biol. (Paris), 53, 448, 10.1016/j.patbio.2004.12.033

Tetu, 2006, The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis, Breast Cancer Res., 8, R28, 10.1186/bcr1503

Tschumperlin, 2004, Mechanotransduction through growth-factor shedding into the extracellular space, Nature, 429, 83, 10.1038/nature02543

van der Slot, 2005, Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels, Biochim. Biophys. Acta, 1741, 95, 10.1016/j.bbadis.2004.09.009

Webster, 1998, Requirement for both Shc and phosphatidylinositol 3′ kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis, Mol. Cell. Biol., 18, 2344, 10.1128/MCB.18.4.2344

White, 2004, Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction, Cancer Cell, 6, 159, 10.1016/j.ccr.2004.06.025

Wipff, 2007, Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix, J. Cell Biol., 179, 1311, 10.1083/jcb.200704042

Wolf, 2007, Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion, Nat. Cell Biol., 9, 893, 10.1038/ncb1616

Yamauchi, 2008, Lysine hydroxylation and cross-linking of collagen, Methods Mol. Biol., 446, 95, 10.1007/978-1-60327-084-7_7

Zaman, 2006, Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis, Proc. Natl. Acad. Sci. USA, 103, 10889, 10.1073/pnas.0604460103

Zhang, 2008, Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer, BMC Cancer, 8, 83, 10.1186/1471-2407-8-83

Zhao, 2008, The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells, J. Biol. Chem., 284, 1385, 10.1074/jbc.M802612200

Zutter, 1998, Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors, J. Mammary Gland Biol. Neoplasia, 3, 191, 10.1023/A:1018798907544