Mathematical modeling of vaporization during laser-induced thermotherapy in liver tissue

Journal of Mathematics in Industry - 2020
Sebastian Blauth1,2, Frank Hübner3, Christian Leithäuser2, Norbert Siedow2, Thomas J. Vogl3
1TU Kaiserslautern, Kaiserslautern, Germany
2Fraunhofer Institute for Industrial Mathematics (ITWM), Kaiserslautern, Germany
3Institute for Diagnostic and Interventional Radiology of the J.W. Goethe University Hospital, Frankfurt/Main, Germany

Tóm tắt

AbstractLaser-induced thermotherapy (LITT) is a minimally invasive method causing tumor destruction due to heat ablation and coagulative effects. Computer simulations can play an important role to assist physicians with the planning and monitoring of the treatment. Our recent study with ex-vivo porcine livers has shown that the vaporization of the water in the tissue must be taken into account when modeling LITT. We extend the model used for simulating LITT to account for vaporization using two different approaches. Results obtained with these new models are then compared with the measurements from the original study.

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Journal of Mathematics in Industry

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