Maternal micronutrients (folic acid and vitamin B12) and omega 3 fatty acids: Implications for neurodevelopmental risk in the rat offspring

Barker, 2004, Developmental origins of adult health and disease, J Epidemiol Community Health, 58, 114, 10.1136/jech.58.2.114 Christian, 2010, Maternal micronutrient deficiency, fetal development, and the risk of chronic disease, J Nutr, 140, 437, 10.3945/jn.109.116327 Owens, 2008, Consequences of poor maternal micronutrition before and during early pregnancy, Trans R Soc Trop Med Hyg, 102, 103, 10.1016/j.trstmh.2007.09.018 Pitkin, 2007, Folate and neural tube defects, Am J Clin Nutr, 85, 285S, 10.1093/ajcn/85.1.285S Indian Council of Medical Research. Evaluation of the national nutritional anaemia prophylaxis programme, an ICMR task force study. Central Electric, New Delhi; 1989. Food and Drug Administration. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Final rule. 21 CFR Parts 136, 137, and 139. Fed Regist 1996;61:8781–7. Freire, 2000, Effect of folic acid fortification in Chile: preliminary results, Eur J Pediatr Surg, 10, 42 Health Canada. Regulations amending the Food and Drug Regulations (1066). Can Gaz Part 1 1997;131:3702–37. Metz, 2002, Changes in serum folate concentrations following voluntary food fortification in Australia, Med J Aust, 176, 90, 10.5694/j.1326-5377.2002.tb04306.x Bower, 2002, Trends in neural tube defects in Western Australia, Aust NZ J Public Health, 26, 150, 10.1111/j.1467-842X.2002.tb00908.x De Wals, 2003, Trend in prevalence of neural tube defects in Quebec, Birth Defects Res A Clin Mol Teratol, 67, 919, 10.1002/bdra.10124 Gucciardi, 2002, Incidence of neural tube defects in Ontario, 1986–1999, CMAJ, 167, 237 Persad, 2002, Incidence of open neural tube defects in Nova Scotia after folic acid fortification, CMAJ, 167, 241 Shane, 2003, Folate fortification: enough already?, Am J Clin Nutr, 77, 8, 10.1093/ajcn/77.1.8 Williams, 2002, Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States, Teratology, 66, 33, 10.1002/tera.10060 Kim, 2004, Will mandatory folic acid fortification prevent or promote cancer?, Am J Clin Nutr, 80, 1123, 10.1093/ajcn/80.5.1123 Carmel, 2008, Efficacy and safety of fortification and supplementation with vitamin B12: biochemical and physiological effects, Food Nutr Bull, 29, S177, 10.1177/15648265080292S121 Smith, 2006, Subacute combined degeneration of the spinal cord in cblC disorder despite treatment with B12, Mol Genet Metab, 88, 138, 10.1016/j.ymgme.2006.02.007 Yajnik, 2006, Vitamin B12 deficiency and hyperhomocysteinemia in rural and urban Indians, J Assoc Physicians India, 54, 775 Rao, 2006, Maternal folic acid supplementation to dams on marginal protein level alters brain fatty acid levels of their adult offspring, Metab Clin Exp, 55, 628, 10.1016/j.metabol.2005.12.008 Dangat, 2009, Long chain polyunsaturated fatty acid composition of breast milk in pre-eclamptic mothers, Neonatology, 97, 190, 10.1159/000252971 Joshi, 2008, High maternal plasma antioxidant concentrations associated with preterm delivery, Ann Nutr Metab, 53, 276, 10.1159/000189789 Kilari, 2009, Long chain polyunsaturated fatty acids in mothers and term babies, J Perinat Med, 37, 513, 10.1515/JPM.2009.096 Kilari, 2009, Long chain polyunsaturated fatty acids in mothers of preterm babies, J Perinat Med, 37, 513, 10.1515/JPM.2009.096 Mehendale, 2008, Fatty acids, antioxidants, and oxidative stress in pre-eclampsia, Int J Gynaecol Obstet, 100, 234, 10.1016/j.ijgo.2007.08.011 Innis, 2008, Dietary omega 3 fatty acids and the developing brain, Brain Res, 1237, 35, 10.1016/j.brainres.2008.08.078 Kale, 2008, Opposite changes in predominantly docosahexaenoic acid (DHA) in cerebrospinal fluid and red blood cells from never-medicated first-episode psychotic patients, Schizophr Res, 98, 295, 10.1016/j.schres.2007.09.036 Kale, 2010, Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients: Implications for altered one-carbon metabolism, Psychiatry Res, 175, 47, 10.1016/j.psychres.2009.01.013 Cannon, 2008, Collaborative Study Group on the Perinatal Origins of Severe Psychiatric Disorders. Decreased neurotrophic response to birth hypoxia in the etiology of schizophrenia, Biol Psychiatry, 64, 797, 10.1016/j.biopsych.2008.04.012 Eriksson, 2005, The fetal origins hypothesis-10 years on, BMJ, 330, 1096, 10.1136/bmj.330.7500.1096 Rees, 2004, Brain development during fetal life: influences of the intra-uterine environment, Neurosci Lett, 361, 111, 10.1016/j.neulet.2004.02.002 Rehn, 2004, An animal model of chronic placental insufficiency: relevance to neurodevelopmental disorders including schizophrenia, Neuroscience, 129, 381, 10.1016/j.neuroscience.2004.07.047 Reeves, 1993, AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet, J Nutr, 123, 1939, 10.1093/jn/123.11.1939 Simopoulos, 1999, Essential fatty acids in health and chronic disease, Am J Clin Nutr, 70, 560S, 10.1093/ajcn/70.3.560s Fritsche, 1988, Rapid autoxidation of fish oil in diets without added antioxidants, J Nutr, 118, 425, 10.1093/jn/118.4.425 Gonzalez, 1992, Lipid peroxidation products are elevated in fish oil diets even in the presence of added antioxidants, J Nutr, 122, 2190, 10.1093/jn/122.11.2190 Ranjekar, 2003, Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients, Psychiatry Res, 121, 109, 10.1016/S0165-1781(03)00220-8 Achon, 2000, High dose folic acid supplementation in rats: effects on gestation and methionine cycle, Br J Nutr, 83, 177, 10.1017/S0007114500000222 Min, 2009, Effects of dietary supplementation of high-dose folic acid on biomarkers of methylating reaction in vitamin B(12)-deficient rats, Nutr Res Pract, 3, 122, 10.4162/nrp.2009.3.2.122 Jen, 2009, Perinatal n-3 fatty acid imbalance affects fatty acid composition in rat offspring, Physiol Behav, 98, 17, 10.1016/j.physbeh.2009.03.031 Joshi, 2003, Fish oil supplementation of rats during pregnancy reduces adult disease risks in their offspring, J Nutr, 133, 3170, 10.1093/jn/133.10.3170 Destaillats, 2010, Differential effect of maternal diet supplementation with alpha-linolenic acid or n-3 long-chain polyunsaturated fatty acids on glial cell phosphatidylethanolamine, phosphatidylserine fatty acid profile in neonate rat brains, Nutr Metab (Lond), 7, 2, 10.1186/1743-7075-7-2 Lucia Bergmann, 2007, Does maternal docosahexaenoic acid supplementation during pregnancy and lactation lower BMI in late infancy?, J Perinat Med, 35, 295, 10.1515/JPM.2007.085 Olsen, 1987, Hypothesis: dietary (N-3)-fatty acids prolong gestation in human beings, Prog Clin Biol Res, 242, 51 Olsen, 1990, A possible preventive effect of low-dose fish oil on early delivery and pre-eclampsia: indications from a 50-year-old controlled trial, Br J Nutr, 64, 599, 10.1079/BJN19900063 Sattar, 1998, Essential fatty acids in relation to pregnancy complications and fetal development, Br J Obstet Gynaecol, 105, 1248, 10.1111/j.1471-0528.1998.tb10002.x Smuts, 2003, A randomized trial of docosahexaenoic acid supplementation during the third trimester of pregnancy, Obstet Gynecol, 101, 469, 10.1016/S0029-7844(02)02585-1 Ansari, 2008, Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury, Free Radic Biol Med, 45, 443, 10.1016/j.freeradbiomed.2008.04.038 Keles, 2010, Antioxidative status and lipid peroxidation in kidney tissue of rats fed with vitamin B(6)-deficient diet, Ren Fail, 32, 618, 10.3109/0886022X.2010.481737 Majumdar, 2009, Folic acid or combination of folic acid and vitamin B(12) prevents short-term arsenic trioxide-induced systemic and mitochondrial dysfunction and DNA damage, Environ Toxicol, 24, 377, 10.1002/tox.20442 Richard, 2007, Methylmalonic acidaemia leads to increased production of reactive oxygen species and induction of apoptosis through the mitochondrial/caspase pathway, J Pathol, 213, 453, 10.1002/path.2248 Das, 2008, Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer’s disease – but how and why?, Prostaglandins Leukot Essent Fatty Acids, 78, 11, 10.1016/j.plefa.2007.10.006 Song, 2000, Polyunsaturated (n-3) fatty acids susceptible to peroxidation are increased in plasma and tissue lipids of rats fed docosahexaenoic acid-containing oils, J Nutr, 130, 3028, 10.1093/jn/130.12.3028 Joshi, 2004, Differential effects of fish oil and folate supplementation during pregnancy in rats on cognitive performance and serum glucose level in their offspring, Nutrition, 20, 465, 10.1016/j.nut.2004.01.012 Vance, 2008, Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids, J Lipid Res, 49, 1377, 10.1194/jlr.R700020-JLR200 Akesson, 1979, Lipid composition and metabolism in liver and brain of vitamin B12-deficient rat sucklings, Br J Nutr, 41, 263, 10.1079/BJN19790035 Bottiglieri, 1996, Folate, vitamin B12, and neuropsychiatric disorders, Nutr Rev, 54, 382, 10.1111/j.1753-4887.1996.tb03851.x Arvindakshan, 2003, Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients, Biol Psychiatry, 53, 56, 10.1016/S0006-3223(02)01443-9 Richardson, 2006, Omega 3 fatty acids in ADHD and related neurodevelopmental disorders, Int Rev Psychiatry, 18, 155, 10.1080/09540260600583031 Wu, 2004, Dietary omega 3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats, J Neurotrauma, 21, 1457, 10.1089/neu.2004.21.1457 Wu, 2008, Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition, Neuroscience, 155, 751, 10.1016/j.neuroscience.2008.05.061