Maternal PD-1 regulates accumulation of fetal antigen-specific CD8+ T cells in pregnancy

Agata, 1996, Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes, Int. Immunol., 8, 765, 10.1093/intimm/8.5.765

Ballif, 2001, Molecular mechanisms mediating mammalian mitogen-activated protein kinase (mapk) kinase (mek)-mapk cell survival signals, Cell Growth Differ., 12, 397

Dong, 2002, Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion, Nat. Med., 8, 793, 10.1038/nm0902-1039c

Dong, 2004, B7-h1 determines accumulation and deletion of intrahepatic CD8+ T lymphocytes, Immunity, 20, 327, 10.1016/S1074-7613(04)00050-0

Erlebacher, 2007, Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus, J. Clin. Invest., 117, 1399, 10.1172/JCI28214

Freeman, 2000, Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation, J. Exp. Med., 192, 1027, 10.1084/jem.192.7.1027

Guleria, 2005, A critical role for the programmed death ligand 1 in fetomaternal tolerance, J. Exp. Med., 202, 231, 10.1084/jem.20050019

Hori, 2006, B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts, J. Immunol., 177, 5928, 10.4049/jimmunol.177.9.5928

Ishida, 1992, Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death, EMBO J., 11, 3887, 10.1002/j.1460-2075.1992.tb05481.x

Keir, 2005, Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes, J. Immunol., 175, 7372, 10.4049/jimmunol.175.11.7372

Keir, 2006, Tissue expression of PD-L1 mediates peripheral T cell tolerance, J. Exp. Med., 203, 883, 10.1084/jem.20051776

Keir, 2007, PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues, J. Immunol., 179, 5064, 10.4049/jimmunol.179.8.5064

Latchman, 2004, PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells, Proc. Natl. Acad. Sci. U.S.A., 101, 10691, 10.1073/pnas.0307252101

Lyons, 1994, Determination of lymphocyte division by flow cytometry, J. Immunol. Methods, 171, 131, 10.1016/0022-1759(94)90236-4

Martin-Orozco, 2006, Cutting edge: programmed death (PD) ligand-1/PD-1 interaction is required for CD8+ T cell tolerance to tissue antigens, J. Immunol., 177, 8291, 10.4049/jimmunol.177.12.8291

Nishimura, 1998, Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses, Int. Immunol., 10, 1563, 10.1093/intimm/10.10.1563

Nishimura, 1999, Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor, Immunity, 11, 141, 10.1016/S1074-7613(00)80089-8

Nishimura, 2001, Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice, Science, 291, 319, 10.1126/science.291.5502.319

Okazaki, 2001, PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine, Proc. Natl. Acad. Sci. U.S.A., 98, 13866, 10.1073/pnas.231486598

Petroff, 2005, Immune interactions at the maternal–fetal interface, J. Reprod. Immunol., 68, 1, 10.1016/j.jri.2005.08.003

Redmond, 2008, The apoptotic pathway contributing to the deletion of naive CD8 T cells during the induction of peripheral tolerance to a cross-presented self-antigen, J. Immunol., 180, 5275, 10.4049/jimmunol.180.8.5275

Taglauer, 2008, The hidden maternal–fetal interface: events involving the lymphoid organs in maternal–fetal tolerance, Int. J. Dev. Biol., 79, 562

Taglauer, 2008, Expression and function of PDCD1 at the human maternal–fetal interface, Biol. Reprod., 79, 562, 10.1095/biolreprod.107.066324

Tanaka, 2007, PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection, J. Immunol., 179, 5204, 10.4049/jimmunol.179.8.5204

Vacchio, 2003, CD28 costimulation is required for in vivo induction of peripheral tolerance in CD8 T cells, J. Exp. Med., 197, 19, 10.1084/jem.20021429

Vacchio, 2005, Fetal expression of fas ligand is necessary and sufficient for induction of CD8 T cell tolerance to the fetal antigen h-y during pregnancy, J. Immunol., 174, 4657, 10.4049/jimmunol.174.8.4657

Vacchio, 1999, The fetus and the maternal immune system: pregnancy as a model to study peripheral T-cell tolerance, Crit. Rev. Immunol., 19, 461

Vermes, 1995, A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V, J. Immunol. Methods, 184, 39, 10.1016/0022-1759(95)00072-I

Wang, 2007, Programmed cell death 1 (PD-1) and its ligand PD-L1 are required for allograft tolerance, Eur. J. Immunol., 37, 2983, 10.1002/eji.200737583

Wang, 2003, Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction, J. Exp. Med., 197, 1083, 10.1084/jem.20021752

White, 2004, Effect of interleukin-10 null mutation on maternal immune response and reproductive outcome in mice, Biol. Reprod., 70, 123, 10.1095/biolreprod.103.018754

Yang, 2008, Critical role of donor tissue expression of programmed death ligand-1 in regulating cardiac allograft rejection and vasculopathy, Circulation, 117, 660, 10.1161/CIRCULATIONAHA.107.741025

Yuan, 2005, Shp-2 phosphatase regulates DNA damage-induced apoptosis and g2/m arrest in catalytically dependent and independent manners, respectively, J. Biol. Chem., 280, 42701, 10.1074/jbc.M506768200