Mast cell transcriptional networks

Arinobu, 2005, Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis, Proc. Natl. Acad. Sci. U. S. A., 102, 18105, 10.1073/pnas.0509148102 Abonia, 2005, Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2, Blood, 105, 4308, 10.1182/blood-2004-09-3578 Gurish, 2001, Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing, J. Exp. Med., 194, 1243, 10.1084/jem.194.9.1243 Kitamura, 1981, Spleen colony-forming cell as common precursor for tissue mast cells and granulocytes, Nature, 291, 159, 10.1038/291159a0 Kitamura, 1977, Development of mast cells from grafted bone marrow cells in irradiated mice, Nature, 268, 442, 10.1038/268442a0 Chen, 2005, Identification of mast cell progenitors in adult mice, Proc. Natl. Acad. Sci. U. S. A., 102, 11408, 10.1073/pnas.0504197102 Arinobu, 2005, Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis, Proc. Natl. Acad. Sci. U. S. A., 102, 18105, 10.1073/pnas.0509148102 Iwasaki, 2006, The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages, Genes Dev., 20, 3010, 10.1101/gad.1493506 Taghon, 2007, Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3, Nat. Immunol., 8, 845, 10.1038/ni1486 McDevitt, 1997, A “knockdown” mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1, Proc. Natl. Acad. Sci. U. S. A., 94, 6781, 10.1073/pnas.94.13.6781 Ghinassi, 2007, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor, Blood, 109, 1460, 10.1182/blood-2006-07-030726 Salmon, 2007, Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene, Blood, 110, 3573, 10.1182/blood-2006-10-053124 Cantor, 2001, Hematopoietic development: a balancing act, Curr. Opin. Genet. Dev., 11, 513, 10.1016/S0959-437X(00)00226-4 Orkin, 2003, Priming the hematopoietic pump, Immunity, 19, 633, 10.1016/S1074-7613(03)00302-9 Orkin, 2000, Diversification of haematopoietic stem cells to specific lineages, Nat. Rev., Genet., 1, 57, 10.1038/35049577 Iwasaki, 2007, Myeloid lineage commitment from the hematopoietic stem cell, Immunity, 26, 726, 10.1016/j.immuni.2007.06.004 Hodgkinson, 1993, Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix–loop–helix-zipper protein, Cell, 74, 395, 10.1016/0092-8674(93)90429-T Moore, 1995, Insight into the microphthalmia gene, Trends Genet., 11, 442, 10.1016/S0168-9525(00)89143-X Stevens, 1982, Mast cells in spotted mutant mice (W Ph mi), Proc. R. Soc. Lond., B Biol. Sci., 215, 405, 10.1098/rspb.1982.0050 Stechschulte, 1987, Effect of the mi allele on mast cells, basophils, natural killer cells, and osteoclasts in C57Bl/6J mice, J. Cell. Physiol., 132, 565, 10.1002/jcp.1041320321 Kitamura, 2006, Molecular mechanisms of mast cell development, Immunol. Allergy Clin. North Am., 26, 387, 10.1016/j.iac.2006.05.004 Shahlaee, 2007, Distinct and shared transcriptomes are regulated by microphthalmia-associated transcription factor isoforms in mast cells, J. Immunol., 178, 378, 10.4049/jimmunol.178.1.378 Takemoto, 2002, The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor, J. Biol. Chem., 277, 30244, 10.1074/jbc.M201441200 Oboki, 2002, Isoforms of mi transcription factor preferentially expressed in cultured mast cells of mice, Biochem. Biophys. Res. Commun., 290, 1250, 10.1006/bbrc.2002.6332 Pevny, 1995, Development of hematopoietic cells lacking transcription factor GATA-1, Development, 121, 163, 10.1242/dev.121.1.163 Ghinassi, 2007, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor, Blood, 109, 1460, 10.1182/blood-2006-07-030726 Migliaccio, 2003, GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant, J. Exp. Med., 197, 281, 10.1084/jem.20021149 Ghinassi, 2007, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor, Blood, 109, 1460, 10.1182/blood-2006-07-030726 Takahashi, 1997, Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene, J. Biol. Chem., 272, 12611, 10.1074/jbc.272.19.12611 Harigae, 1998, Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells, Genes Cells, 3, 39, 10.1046/j.1365-2443.1998.00166.x Maeda, 2003, Regulation of cell type-specific mouse Fc epsilon RI beta-chain gene expression by GATA-1 via four GATA motifs in the promoter, J. Immunol., 170, 334, 10.4049/jimmunol.170.1.334 Nishiyama, 1999, The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor alpha-chain gene, J. Immunol., 163, 623, 10.4049/jimmunol.163.2.623 Zon, 1991, GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene, J. Biol. Chem., 266, 22948, 10.1016/S0021-9258(18)54446-X Henkel, 1994, PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer, Proc. Natl. Acad. Sci. U. S. A., 91, 7737, 10.1073/pnas.91.16.7737 Masuda, 2004, The interaction between GATA proteins and activator protein-1 promotes the transcription of IL-13 in mast cells, J. Immunol., 173, 5564, 10.4049/jimmunol.173.9.5564 Tsai, 1994, An early haematopoietic defect in mice lacking the transcription factor GATA-2, Nature, 371, 221, 10.1038/371221a0 Tsai, 1997, Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation, Blood, 89, 3636, 10.1182/blood.V89.10.3636 Iwasaki, 2005, Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation, Blood, 106, 1590, 10.1182/blood-2005-03-0860 Dakic, 2005, PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis, J. Exp. Med., 201, 1487, 10.1084/jem.20050075 Walsh, 2002, Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates, Immunity, 17, 665, 10.1016/S1074-7613(02)00452-1 DeKoter, 2000, Regulation of B lymphocyte and macrophage development by graded expression of PU.1, Science, 288, 1439, 10.1126/science.288.5470.1439 Nishiyama, 2004, Overproduction of PU.1 in mast cell progenitors: its effect on monocyte-and mast cell-specific gene expression, Biochem. Biophys. Res. Commun., 313, 516, 10.1016/j.bbrc.2003.11.145 Ito, 2005, Mast cells acquire monocyte-specific gene expression and monocyte-like morphology by overproduction of PU.1, J. Immunol., 174, 376, 10.4049/jimmunol.174.1.376 Shelburne, 2003, Stat5 expression is critical for mast cell development and survival, Blood, 102, 1290, 10.1182/blood-2002-11-3490 Witte, 1990, Steel locus defines new multipotent growth factor, Cell, 63, 5, 10.1016/0092-8674(90)90280-R Fukao, 2002, Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice, Nat. Immunol., 3, 295, 10.1038/ni768 Gu, 2001, Essential role for Gab2 in the allergic response, Nature, 412, 186, 10.1038/35084076 Malaviya, 2001, Role of Janus kinase 3 in mast cell-mediated innate immunity against gram-negative bacteria, Immunity, 15, 313, 10.1016/S1074-7613(01)00184-4 Arinobu, 2005, Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis, Proc. Natl. Acad. Sci. U. S. A., 102, 18105, 10.1073/pnas.0509148102 Iwasaki, 2006, The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages, Genes Dev., 20, 3010, 10.1101/gad.1493506 Iwasaki, 2006, The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages, Genes Dev., 20, 3010, 10.1101/gad.1493506 Zhang, 1999, Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1, Proc. Natl. Acad. Sci. U. S. A., 96, 8705, 10.1073/pnas.96.15.8705 Zhang, 2000, PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding, Blood, 96, 2641, 10.1182/blood.V96.8.2641 Rekhtman, 1999, Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells, Genes Dev., 13, 1398, 10.1101/gad.13.11.1398 Henkel, 1994, PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer, Proc. Natl. Acad. Sci. U. S. A., 91, 7737, 10.1073/pnas.91.16.7737 Masuda, 2004, The interaction between GATA proteins and activator protein-1 promotes the transcription of IL-13 in mast cells, J. Immunol., 173, 5564, 10.4049/jimmunol.173.9.5564 Walsh, 2002, Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates, Immunity, 17, 665, 10.1016/S1074-7613(02)00452-1 Takemoto, 2002, The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor, J. Biol. Chem., 277, 30244, 10.1074/jbc.M201441200 Minegishi, 1998, Alternative promoters regulate transcription of the mouse GATA-2 gene, J. Biol. Chem., 273, 3625, 10.1074/jbc.273.6.3625 Fordham, 1999, Chromatin structure and transcriptional regulation of the stem cell leukaemia (SCL) gene in mast cells, Leukemia, 13, 750, 10.1038/sj.leu.2401420 Bockamp, 1998, Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1, J. Biol. Chem., 273, 29032, 10.1074/jbc.273.44.29032 McDevitt, 1997, An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice, Proc. Natl. Acad. Sci. U. S. A., 94, 7976, 10.1073/pnas.94.15.7976 Nishimura, 2000, A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene, Mol. Cell. Biol., 20, 713, 10.1128/MCB.20.2.713-723.2000 Onodera, 1997, GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis, Proc. Natl. Acad. Sci. U. S. A., 94, 4487, 10.1073/pnas.94.9.4487 Nishimura, 2000, A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene, Mol. Cell. Biol., 20, 713, 10.1128/MCB.20.2.713-723.2000 Onodera, 1997, GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis, Proc. Natl. Acad. Sci. U. S. A., 94, 4487, 10.1073/pnas.94.9.4487 McDevitt, 1997, A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1, Proc. Natl. Acad. Sci. U. S. A., 94, 6781, 10.1073/pnas.94.13.6781 Shivdasani, 1997, A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development, EMBO J., 16, 3965, 10.1093/emboj/16.13.3965 Vannucchi, 2001, Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice), Blood, 97, 3040, 10.1182/blood.V97.10.3040 Guyot, 2004, Deletion of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and eosinophil differentiation, Blood, 104, 89, 10.1182/blood-2004-01-0108 Ghinassi, 2007, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor, Blood, 109, 1460, 10.1182/blood-2006-07-030726 Migliaccio, 2003, GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant, J. Exp. Med., 197, 281, 10.1084/jem.20021149 Takahashi, 1997, Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene, J. Biol. Chem., 272, 12611, 10.1074/jbc.272.19.12611 Takahashi, 1998, Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo, Blood, 92, 434, 10.1182/blood.V92.2.434 Harigae, 1998, Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells, Genes Cells, 3, 39, 10.1046/j.1365-2443.1998.00166.x Yu, 2002, Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo, J. Exp. Med., 195, 1387, 10.1084/jem.20020656 Valverde-Garduno, 2004, Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis-element identification, Blood, 104, 3106, 10.1182/blood-2004-04-1333 Litt, 2001, Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci, EMBO J., 20, 2224, 10.1093/emboj/20.9.2224 Ronchi, 1997, Molecular heterogeneity of regulatory elements of the mouse GATA-1 gene, Genes Funct., 1, 245, 10.1046/j.1365-4624.1997.00021.x McDevitt, 1997, An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice, Proc. Natl. Acad. Sci. U. S. A., 94, 7976, 10.1073/pnas.94.15.7976 Vyas, 1999, Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene, Development, 126, 2799, 10.1242/dev.126.12.2799 Valverde-Garduno, 2004, Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis-element identification, Blood, 104, 3106, 10.1182/blood-2004-04-1333 Ronchi, 1997, Molecular heterogeneity of regulatory elements of the mouse GATA-1 gene, Genes Funct., 1, 245, 10.1046/j.1365-4624.1997.00021.x Tsai, 1991, Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter, Genes Dev., 5, 919, 10.1101/gad.5.6.919 Seshasayee, 2000, Intron 1 elements promote erythroid-specific GATA-1 gene expression, J. Biol. Chem., 275, 22969, 10.1074/jbc.M002931200 Chen, 2005, Identification of mast cell progenitors in adult mice, Proc. Natl. Acad. Sci. U. S. A., 102, 11408, 10.1073/pnas.0504197102 Zeller, 2001, Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation, J. Biol. Chem., 276, 48285, 10.1074/jbc.M108506200 Boyer, 2005, Core transcriptional regulatory circuitry in human embryonic stem cells, Cell, 122, 947, 10.1016/j.cell.2005.08.020 Rekhtman, 1999, Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells, Genes Dev., 13, 1398, 10.1101/gad.13.11.1398 Tsuzuki, 2004, Cross talk between retinoic acid signaling and transcription factor GATA-2, Mol. Cell. Biol., 24, 6824, 10.1128/MCB.24.15.6824-6836.2004 Tsuzuki, 2000, Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoprotein, Mol. Cell. Biol., 20, 6276, 10.1128/MCB.20.17.6276-6286.2000 Tsuzuki, 2002, Interactions of GATA-2 with the promyelocytic leukemia zinc finger (PLZF) protein, its homologue FAZF, and the t(11;17)-generated PLZF-retinoic acid receptor alpha oncoprotein, Blood, 99, 3404, 10.1182/blood.V99.9.3404 Tsang, 1997, FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation, Cell, 90, 109, 10.1016/S0092-8674(00)80318-9 Chang, 2002, GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis, Proc. Natl. Acad. Sci. U. S. A., 99, 9237, 10.1073/pnas.142302099 Sato, 1999, Microphthalmia-associated transcription factor interacts with PU.1 and c-Fos: determination of their subcellular localization, Biochem. Biophys. Res. Commun., 254, 384, 10.1006/bbrc.1998.9918 Hu, 2007, Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors, Mol. Cell. Biol., 27, 4018, 10.1128/MCB.01839-06 Luchin, 2001, Genetic and physical interactions between microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation, J. Biol. Chem., 276, 36703, 10.1074/jbc.M106418200 Henkel, 1994, PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer, Proc. Natl. Acad. Sci. U. S. A., 91, 7737, 10.1073/pnas.91.16.7737 Krysinska, 2007, A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene, Mol. Cell. Biol., 27, 878, 10.1128/MCB.01915-06 Bert, 2007, A modular enhancer is differentially regulated by GATA and NFAT elements that direct different tissue-specific patterns of nucleosome positioning and inducible chromatin remodeling, Mol. Cell. Biol., 27, 2870, 10.1128/MCB.02323-06 Ghinassi, 2007, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor, Blood, 109, 1460, 10.1182/blood-2006-07-030726 Migliaccio, 2003, GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant, J. Exp. Med., 197, 281, 10.1084/jem.20021149 Harigae, 1998, Differential roles of GATA-1 and GATA-2 in growth and differentiation of mast cells, Genes Cells, 3, 39, 10.1046/j.1365-2443.1998.00166.x Pevny, 1995, Development of hematopoietic cells lacking transcription factor GATA-1, Development, 121, 163, 10.1242/dev.121.1.163 Ghinassi, 2007, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor, Blood, 109, 1460, 10.1182/blood-2006-07-030726 Tsai, 1994, An early haematopoietic defect in mice lacking the transcription factor GATA-2, Nature, 371, 221, 10.1038/371221a0 Tsai, 1997, Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation, Blood, 89, 3636, 10.1182/blood.V89.10.3636 Scott, 1994, Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages, Science, 265, 1573, 10.1126/science.8079170 McKercher, 1996, Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities, EMBO J., 15, 5647, 10.1002/j.1460-2075.1996.tb00949.x Walsh, 2002, Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates, Immunity, 17, 665, 10.1016/S1074-7613(02)00452-1 Moore, 1995, Insight into the microphthalmia gene, Trends Genet., 11, 442, 10.1016/S0168-9525(00)89143-X Ebi, 1990, Mechanism of mast cell deficiency in mutant mice of mi/mi genotype: an analysis by co-culture of mast cells and fibroblasts, Blood, 75, 1247, 10.1182/blood.V75.6.1247.1247 Shelburne, 2003, Stat5 expression is critical for mast cell development and survival, Blood, 102, 1290, 10.1182/blood-2002-11-3490 Chen, 2005, Identification of mast cell progenitors in adult mice, Proc. Natl. Acad. Sci. U. S. A., 102, 11408, 10.1073/pnas.0504197102 Arinobu, 2005, Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis, Proc. Natl. Acad. Sci. U. S. A., 102, 18105, 10.1073/pnas.0509148102 Iwasaki, 2006, The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages, Genes Dev., 20, 3010, 10.1101/gad.1493506 Taghon, 2007, Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3, Nat. Immunol., 8, 845, 10.1038/ni1486 Boyd, 1998, c-Myc target gene specificity is determined by a post-DNA binding mechanism, Proc. Natl. Acad. Sci. U. S. A., 95, 13887, 10.1073/pnas.95.23.13887