Behrens J, Birchmeier W, Goodman SL, Imhof BA (1985) Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-Arc 1: Mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol 101: 1307–1315
Behrens J, Mareel MM, Van Roy FM, Birchmeier W (1989) Dissecting tumor cell invasion: Epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol 108: 2435–2447
Birchmeier W, Weidner KM, Schipper J, Behrens J (1993) Molekulare Aspekte der Invasion von Krebszellen. In: Rübben H, Goepel M, Schmitz-Dräger BJ (Hrsg) Immuntherapie in der Uroonko-logie. Springer, Berlin Heidelberg New York
Böhm M, Totzeck B, Birchmeier W, Wieland I (1994) Differences of E-cadherin expression levels and patterns in primary and metastatic human lung cancer. Clin Exp Metastasis 12: 55–62
Boller K, Vestweber D, Kemler R (1985) Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. J Cell Biol 100: 327–332
Bringuier PP, Umbas R, Schaafsma HE, Karthaus HFM, De-Bruyne FMJ, Schalken JA (1993) Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Res 53: 3241–3245
Delakas D, Agnantis NJ, Parliaras I, Cranidis A, Spandidos DA (1992) The role of ras p21 oncoprotein in human bladder cancer. In: Olsson CA (ed) Oncogenes and molecular genetics of urological tumors. Churchill Livingstone, Philadelphia, pp 91–94
Descotes F, Bittard H, Adessi GL (1992) Study of ras gene alterations in human bladder tumors. In: Olsson CA (ed) Oncogenes and molecular genetics of urological tumors. Churchill Livingstone, Philadelphia, pp 95–102
Edelman GM, Gallin WJ, Delouvee A, Cunningham BA, Thiery JP (1983) Early epochal maps of two different cell adhesion molecules. Proc Natl Acad Sci USA 80: 4384–4388
El-Ahmady O, El-Din AG, Khalaf I (1993) Comparison between TPA and CA 50 expression in Egyptian bladder cancer patients. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, research trends. Zuckerschwerdt, München Bern, S 89
Fischer C, Terpe H, Weidner W, Storkel S, Gunthert U (1995) Significance of cell adhesion molecules for dedifferentiated processes in renal cell carcinomas. J Urol 153: 340
Fradet Y, Tetu B, Veilleux C, Allard P (1994) Prevalence and clinical significance of p53, Rb and HER-2/neu expression in newly diagnosed superficial bladder tumors. J Urol A 151: 859, 442
Frixen U, Behrens J, Sachas M et al. (1991) E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 111: 173–185
Galle P (1993) Detection of p53-antibodies by immunoblot and ELISA in various human malignancies — A new serological test? In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, p 179
Gu FL, Shen JC, Zhou AR, Ge ZL (1992) Amplification and expression of the c-erb B-2/neu and c-myc proto-oncogenes in bladder cancer and renal cell carcinoma. In: Olsson CA (ed) Oncogenes and molecular genetics ofurological tumors. Churchill Livingstone, Philadelphia, pp 103–110
Heicappell R, Sartorius S, Miller K (1995) Loss of E-and N-cadherins in advanced renal cell carcinoma (RCC). J Urol 153: 635
Imhof BA, Vollmers HP, Goodman SL, Birchmeier W (1983) Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody. Cell 35: 667–675
Kakizoe T, Fujimoto K, Terada M (1992) Oncogenes and molecular genetics ofbladder cancer. In: Olsson CA (ed) Oncogenes and molecular genetics ofurological tumors. Churchill Livingstone, Philadelphia, pp 23–28
Katzenwadel A, Schultze-Seemann W, Sommerkamp H (1993) Plasma-SCC-Spiegel bei Patienten mit Harnblasenkarzinom. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, p 90
Koch PJ, Walsh MJ, Schmelz M, Goldschmidt MD, Zimbelman R, Franke WW (1990) Identification of desmoglein, a constitutive desmosomal glycoprotein as a member of the cadherin family of cell adhesion molecules. Eur J Cell Biol 53: 1–12
Kohn EC (1990) L65 15 82: a novel antiproliferative and antimetastasis agent. JNCI 82: 54–60
Kohn EC, Liotta LA, Schiffmann E (1990) Auto-crine motility factor stimulates a three-fold increase in inositol trisphosphate in human melanoma cells. Biochem Biophys Res Comm 166: 757–764
Kuczyk MA, Serth J, Allhoff EP, Jonas U (1993) Das p53-Tumorsuppressorgen als neuer Prognosefaktor für den klinischen Verlauf von Harnblasenkarzinomen. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, p 177
Liotta LA, Mandler R, Murano G, Katz DA, Gordon RK, Hing PK, Schiffmann E (1986) Tumor cell autocrine motility factor. Proc Natl Acad Sci USA 83: 3302–3306
Lipponen PK, Eskelinen MJ, Nordling S (1991) Nucleolar organizer regions (AgNORs) as predictors in transitional cell bladder cancer. Br J Cancer 64: 1139–1144
Mareel MM (1983) Invasion in vitro: Methods of analysis. Cancer Metastasis Rev 2: 201–218
Mechanic S, Raynor K, Hill JE, Cowin P (1991) Desmocollins form a distinct subset of the cadherin family of cell adhesion molecules Proc Natl Acad Sci USA 88: 4476–4480
Mulder AH, Van Hootegem JCSP, Sylvester R, Ten Kate FJW, Kurth KH, Ooms ECM vand der Kwast TH (1992) Prognostic factors in Bladder Carcinoma: histologic parameters and expression of a cell cycle-related nuclear antigen (Ki67). J Pathol 66: 37–43
Nacapoulou L, Zervas A, Dimopoulos C (1992) Im-munohistochemical expression of epidermal growth factor receptor and protooncogene erb B-2 in bladder carcinoma. In: Olsson CA (ed) Oncogenes and molecular genetics ofurological tumors. Churchill Livingstone, Philadelphia, pp 113–120
Nagafuchi A, Shirayoshi Y, Okazaki K, Yasuda K, Takeichi M (1987) Transformation ofcell adhesion properties by exogenously introduced E-cadherin cDNA. Nature (London) 329: 241–243
Nemoto R, Hattori K, Uchida K, Shimazui T, Koiso K, Harada M (1990) Estimation of growth fraction in situ in human bladder cancer with Bromo-deoxyuridine labelling. Br J Urol 65: 27–31
O’Brien T, Smith K, Cranston D, Fuggle S, Bicknell T, Harris A (1995) Urinary basic fibroblast growth factor in patients with bladder cancer and benign prostatic hypertrophy. Br J Urol 76: 311–314
Okamura K, Miyake K, Koshikawa T, Asai J (1990) Growth fractions of transitional cell carcinomas of the bladder defined by the monoclonal antibody Ki-67. J Urol 144: 875–878
Otto T, Rembrink K, Goepel M, Meyer-Schwickerath M, Rübben H (1992) E-cadherin: a marker for differentiation and invasiveness in prostatic carcinoma. Urol Res 21: 359–362
Otto T, Steinberg F, Goepel M, Rübben H (1994) Kapillardichte bei Harnblasenkarzinomen und normalem Urothel. Urologe A 1: 107
Otto T, Birchmeier W, Schmidt U, Hinke A, Schipper J, Rübben H, Raz A (1994) Inverse relation of E-Cadherin and autocrine motility factor receptor expression as prognostic factors in patients with bladder carcinoma. Cancer Res 54: 3120–3123
Pfisterer J, Winter O, Frixen UH, Behrens J, Eberle G, Birchmeier W, Bauknecht T (1990) Arc-1/uvo-morulin by immunohistochemistry in non-malignant tissue and in ovarian tumors. J Cancer Res Clin Oncol 116: 182–187
Popov Z, Colombel M, Chopin D (1993) Evaluation of proliferation and p53 overexpression in bladder cancer. Urol Res 21: 451
Popov Z, Diez SG, Hoznek A, Radvayi F, Bellot J, Abbou CC, Chopin D (1995) Decreased E-cadherin expression by immunohistochemistry is strongly correlated with stage and grade in bladder cancer. J Urol 153: 1182
Rhode D, Küsters R, Jakse G (1993) ICAM-1 im Urin von Blasentumorpatienten. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, pp 92–98
Rhode D, Küsters R, Jakse G (1993) ICAM-1 im Urin von Blasentumorpatienten. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, pp 92–98
Ringwald M, Schuh R, Vestweber D et al. (1987) The structure of the cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion. EMBOJ 6: 3647–3653
Rodriguez-Boulan E, Nelson WJ (1989) Morphogenesis of the polarized epithelial cell phenotype. Science 245: 718–725
Rosen EM, Goldberg ID, Kacinski BM, Buckholz T, Vinter DW (1989) Smooth muscle releases an epithelial cell scatter factor which binds to heparin. In Vitro Cell Dev Diol 25: 163–168
Saito B et al. (1990) Chemical induced bladder carcinoma in mice. Nippon Hinyokikka Gakka Zasshi 81: 993–996
Sato T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y (1990) Allelo-type of breast cancer: cummulative allele losses promote tumor progression in primary breast cancer. Cancer Res 50: 7184–7189
Schipper JH, Frixen UH, Behrens J, Unger A, Jahncke K, Birchmeier W (1991) E-cadherin expression in squamous cell carcinomas ofhead and neck: Inverse correlation with tumor differentiation and lymph node metastasis. Cancer Res 51: 6328–6337
Schultze-Seemann W, Sommerkamp H (1993) SCC im Urin — Ein möglicher Tumormarker bei Patienten mit einem Transitionalzellkarzinom. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, p 91
Shimoyama Y, Hirohashi S (1991) Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 51: 2185–2192
Shirayoshi Y, Okada TS, Takeichi M (1983) The calcium-dependent cell-cell adhesion system regulates inner cell mass formation and cell surface polarization in early mouse development. Cell 35: 631–638
Slamon DJ, Dekernion JB, Verma IM, Cline MJ (1989) Expression of cellular oncogenes in human malignancies. Science 224: 256–262
Soloway MS, Lamm DL, Fischer LN (1993) TPA-IRMA in regional and systemic staging of TCC of the urinary tract. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, p 93
Stoker M (1989) Effect of scatter factor on motility of epithelial cells and fibroblasts. J Cell Physiol 139: 565–572
Stoker M, Gherhardi E, Perryman M, Gray J (1987) Scatter factor is a fibroblast-derived modulator of epithelial cell motility. Nature 327: 239–244
Stracke ML, Guirguis R, Liotta LA, Schiffmann E (1987) Pertussis toxin inhibits stimulated motility independently of the adenylate cyclase pathway in human melanoma cells. Biochem Biophys Res Comm 164: 339–345
Tsujihashi H, Nakanishi A, Matsuda H, Uejima S, Kurita T (1991) Cell proliferation ofhuman bladder tumors determined by BrdUrd and Ki-67 immunostaining. J Urol 145: 846–849
Tunn UW, Jaworek D (1993) Simultane Bestimmung von Cytokin-Fragmenten mit TPA und CYFRA 21-1 im Serum beim Urothelkarzinom der Harnblase. In: Klapdor R (ed) Current tumor diagnosis: applications, clinical relevance, researchtrends. Zuckerschwerdt, München Bern, p 94
Vleminckx K, Vakat L Jr, Mareel M, Fiers W, Van Roy F (1991) Genetics manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66: 107–119
Warn RM, Dowrick P (1989) Motility factors on the march. Nature 340: 186–190
Weidner KM, Arakaki N, Hartmann G et al. (1991) Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci USA 88: 7001–7005
Weidner KM, Behrens J, Vandekerckhove J, Birchmeier W (1990) Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 111: 2097–2108