Mandibular cuniculatum carcinoma: Apropos of 3 cases and literature review

Head and Neck - Tập 34 Số 2 - Trang 291-295 - 2012
Y. Pons1, Siham Kerrary1, Amanda J. Cox1, A. Guerre1, Chloé Bertolus1, Françoise Gruffaz2, Frédérique Capron2, P. Goudot1, Blandine Ruhin‐Poncet1
1Oral and Maxillofacial Surgery Department, Assistance Publique des Hôpitaux de Paris, Pitié-Salpêtrière University Hospital, Pierre and Marie Curie University, Paris, France.
2Pathology Department, Assistance Publique des Hôpitaux de Paris, Pitié–Salpêtrière University Hospital, Pierre and Marie Curie University, Paris, France

Tóm tắt

AbstractBackgroundCuniculatum carcinoma is a well‐differentiated form of squamous cell carcinoma that shares histologic characteristics with papillary squamous cell carcinoma and verrucous carcinoma. Cuniculatum carcinoma usually occurs on the plantar region, and only 16 cases involving the oral cavity have been described in the literature.MethodsThe authors have reported 3 cases of mandibular cuniculatum carcinoma. All of the patients were in a great deal of pain. Histologic diagnosis was difficult due to the presence of few cellular atypies. Clinical criteria, osseous lysis, and the coexistence of multiple intraosseous well‐differentiated, hyperkeratotic papillomatous lesions with few cellular atypies sign the diagnosis.ResultsNo local recurrence has been reported after treatment with radical surgery alone.ConclusionThe diagnosis is often delayed. Although cuniculatum carcinoma displays aggressive behavior locally, lymph node infiltration and metastasis are rare. The therapy of choice is surgical removal with free margins, after which the prognosis is excellent. © 2010 Wiley Periodicals, Inc. Head Neck, 2012

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Tài liệu tham khảo

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Head and Neck

Tập 34 Số 2

291-295

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