Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019

European Urology - Tập 77 Số 4 - Trang 508-547 - 2020
Silke Gillessen1,2,3,4,5, Gerhardt Attard6, Tomasz M. Beer7, Himisha Beltran8,9, Anders Bjartell10, Alberto Bossi11, Alberto Briganti12, Robert G. Bristow13,14,15, Kim N.16, Noel W. Clarke17, Ian D. Davis18, Johann S. de Bono19, Charles G. Drake20, Ignacio Durán21, Rosalind A. Eeles22, Eleni Efstathiou23, Christopher P. Evans24, Stefano Fanti25, Felix Y. Feng26, Karim Fizazi27, Mark Frydenberg28,29,30, Martin Gleave31, Susan Halabi32, Axel Heidenreich33,34, Daniel Heinrich35,36, Celestia S. Higano37, Michael S. Hofman38,39, Maha Hussain, Nicholas D. James40,41, Ravindran Kanesvaran42,43, Philip W. Kantoff32,44, Raja B. Khauli38,45, Raya Leibowitz‐Amit46,47, C. Logothetis24, Pedro Luiz Serrano Usón48,49, Robin Millman39, Alicia K. Morgans40, Michael J. Morris29,27,43,44, Nicolas Mottet29,27,45,50,30,51, Hind M’rabti, Declan G. Murphy28,52,30,53,31, Vedang Murthy28,32,39,54,31, William Oh19, Piet Ost35,33,34,55,36, Joe M. O’Sullivan56,57,35,39,36, Anwar R. Padhani37,58,59,39,60,61,62, Chris Parker24, Darren M.C. Poon41, Colin C. Pritchard40, Robert E. Reiter40,41, Mack Roach42,43,41,63,44,64, Mark A. Rubin65,42,43,44, Charles J. Ryan38,66,45, Fred Saad67,38,27,45, Juan Pablo Sade68,46,47,69, Oliver Sartor70, Howard I. Scher48,71,72,73,74, Neal D. Shore48,49,71,42,43, Eric J. Small49,42,43,45,39,63,64, Matthew R. Smith27,43, Howard R. Soule29,27,43, Cora N. Sternberg28,29,27,50,30,51, Thomas Steuber28,29,52,50,30,51,31, Hiroyoshi Suzuki28,52,30,53,31, Christopher J. Sweeney24, Matthew R. Sydes32,54,31, Mary-Ellen Taplin8,9,32,34,75,39,54, Bertrand Tombal33,34,75, Levent Türkeri56,57,35,33,34,55,36, Inge M. van Oort56,57,35,33,55,36, A. Zapatero35,37,58,59,60,36,61,62, Aurelius Omlin37,58,59,5,60,61,62
1Cantonal Hospital, St. Gallen, Switzerland
2Division of Cancer Science, University of Manchester, Manchester, UK
3Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
4Universita della Svizzera Italiana, Lugano, Switzerland
5University of Bern, Bern, Switzerland
6University College London Cancer Institute, London, UK
7Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA
8Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
9Dana-Farber Cancer Institute, Boston, MA, USA
10Department of Urology, Skåne University Hospital, Malmö, Sweden
11Genito Urinary Oncology, Prostate Brachytherapy Unit, Goustave Roussy, Paris, France
12Unit of Urology/Division of Oncology, URI, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy
13CRUK Manchester Institute and Cancer Centre, Manchester, UK
14Christie NHS Trust, Manchester, UK
15Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
16BC Cancer, Vancouver Prostate Centre, University of British Columbia, Vancouver, British Columbia, Canada
17The Christie and Salford Royal Hospitals, Manchester, UK
18Monash University and Eastern Health, Victoria, Australia
19The Institute of Cancer Research/Royal Marsden NHS Foundation Trust, Surrey, UK
20Division of Haematology/Oncology, Columbia University Medical Center, New York, NY, USA
21Department of Medical Oncology. Hospital Universitario Marques de Valdecilla, IDIVAL, Santander, Cantabria, Spain
22The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK
23University of Texas/MD Anderson Cancer Center, Houston, TX USA
24University of California, Davis, School of Medicine, Sacramento, CA, USA
25Policlinico S.Orsola, Università di Bologna, Italy
26University of California, San Francisco; San Francisco; CA; USA
27Institut Gustave Roussy, University of Paris Sud, Villejuif, France
28Department Anatomy & Developmental Biology, Faculty of Nursing, Medicine & Health Sciences, Monash University, Melbourne, Australia;
29Department of Surgery, Monash University, Melbourne, Australia
30Prostate Cancer Research Program, Monash University, Melbourne, Australia;
31Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada;
32Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA
33Department of Urology, Medical University Vienna, Austria
34Department of Urology, Uro-Oncology, Robot-Assisted and Reconstructive Urology, University of Cologne, Cologne, Germany
35Department of Oncology, Akershus University Hospital, Lørenskog, Norway
36jj University of Washington, Seattle, WA, USA;
37Fred Hutchinson Cancer Research Center, Seattle, WA, USA
38Department of Urology, American University of Beirut Medical center, Beirut, Lebanon
39Peter MacCallum Cancer Centre, Melbourne, Australia
40Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA
41The Institute of Cancer Research, London, UK
42Division of Medical Oncology, National Cancer Centre, Singapore; qq Department of Medicine,
43Memorial Sloan Kettering Cancer Center, New York, NY, USA
44Weill Cornell Medical College, New York, NY, USA
45Naef K. Basile Cancer Institute (NKBCI), American University of Beirut Medical Center, Beirut, Lebanon;
46MD Anderson Cancer Centre, Houston, TX, USA
47Oncology institute, Shamir Medical Center and Faculty of medicine, Tel-Aviv University, Israel; vv Department of Genitourinary Medical Oncology,
48Beneficiência Portuguesa de São Paulo, São Paulo, SP, Brasil;
49Departamento de Oncologia, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; zz UK;
50National Institute of Oncology, University hospital, Rabat, Morocco;
51University Hospital Nord, St Etienne, France
52Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Australia
53Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia
54Tata Memorial Centre, Mumbai, India
55Radiation Oncology, Ghent University Hospital, Ghent, Belgium
56Belfast City Hospital, Belfast, Northern Ireland, UK
57Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, UK; jjj Radiotherapy Department, Cancer Centre,
58Hong Kong Sanatorium & Hospital, The Chinese University of Hong Kong, Hong Kong; nnn Department of Laboratory Medicine,
59Mount Vernon Cancer Centre and Institute of Cancer Research, London, UK
60University of Washington. Seattle, WA USA
61lll Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK; mmm Comprehensive Oncology Centre,
62ooo University of California Los Angeles, Los Angeles, CA, USA;
63UCSF Helen Diller Family Comprehensive Cancer Center University of California–San Francisco San Francisco CA USA
64qqq Bern Center for Precision Medicine, Bern, Switzerland;
65Department for BioMedical Research, University of Bern, Bern, Switzerland
66Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA;
67Centre Hospitalier de Université de Montréal, Montreal, Canada;
68Instituto Alexander Fleming, Buenos Aires, Argentina
69vvv Tulane Cancer Center, New Orleans, LA, USA;
70Department of Oncology, University of Melbourne, Melbourne, Australia
71Department of Clinical Therapeutics, David H. Koch Centre, University of Athens Alexandra Hospital, Athens, Greece;
72Department of Medicine, Weill Cornell Medical College, New York, NY, USA
73Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
74yyy Carolina Urologic Research Center, Myrtle Beach, SC, USA; zzz Massachusetts General Hospital Cancer Center, Boston, MA, USA; aaaa Prostate Cancer Foundation, Santa Monica, CA, USA; bbbb Division of Hematology and Oncology, Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA; cccc Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany; dddd Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany; eeee Toho University Sakura Medical Center, Chiba, Japan; ffff MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK; gggg Cliniques Universitaires Saint Luc, Brussels, Belgium; hhhh Department of Urology, M.A. Aydınlar Acıbadem University, Altunizade Hospital, Istanbul, Turkey; iiii Radboud University Medical Center, Nijmegen, The Netherlands; jjjj Department of Radiation Oncology, University Hospital La Princesa, Health Research Institute, Madrid, Spain; kkkk Department of Medical Oncology and Haematology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland
75Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, The Tisch Cancer Institute, New York, NY, USA;

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