Magnetic resonance imaging findings of the mass‐forming type of autoimmune pancreatitis: Comparison with pancreatic adenocarcinoma

Journal of Magnetic Resonance Imaging - Tập 36 Số 1 - Trang 188-197 - 2012
Bo Yun Hur1, Jeong Min Lee1, Jeong Eun Lee2, Jae Yong Park1, Soo Jin Kim3, Ijin Joo1, Cheong‐Il Shin1, Jee Hyun Baek1, Jung Hoon Kim1, Joon Koo Han1, Byung Ihn Choi1
1Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, Seoul, Korea
2Department of Radiology, Chungnam National University Hospital, Daejeon, Korea
3Department of Radiology, National Cancer Center, Gyeonggi‐do, Korea

Tóm tắt

AbstractPurpose:To determine the characteristic magnetic resonance imaging (MRI) features of mass‐forming autoimmune pancreatitis (AIP), which allow its differentiation from pancreatic adenocarcinoma (PAC).Materials and Methods:MR images of 37 patients with either pathologically proven, mass‐forming AIPs (n = 9) or PACs (n = 28) were retrospectively reviewed. The pancreatic MR protocol included unenhanced images, contrast‐enhanced dynamic images, diffusion‐weighted imaging (DWI), and MR‐cholangiopancreatography (MRCP). Two reviewers analyzed the MR images regarding the number, location, morphologic features, and enhancement degree and pattern of the lesions as well as secondary changes of the pancreatic parenchyma, the biliary and pancreatic ducts. The size and apparent diffusion coefficient (ADC) values of the lesions were measured.Results:Although sensitivities were low (28.6%–44.4%), specificities of multiplicity, capsule‐like rim enhancement, and skipped stricture of the biliary or pancreatic duct in mass‐forming AIP were high (100%). Sensitivities and specificities of irregular or geographic shape, delayed enhancement, and a low ADC value <1.26 × 10−3 mm2/s in mass‐forming AIP were favorable (71.4%–83.3% and 78.5%–89.3%).Conclusion:Although to differentiate mass‐forming AIP from pancreatic cancer is difficult, the combination of MRI findings including contrast‐enhanced dynamic images, MRCP, and DWI can be a help. J. Magn. Reson. Imaging 2012;36:188–197. © 2012 Wiley Periodicals, Inc.

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