Macrophages enhance mesenchymal stem cell osteogenesis via down-regulation of reactive oxygen species

Journal of Dentistry - Tập 94 - Trang 103297 - 2020
Meng-lin Luo1, Yang Jiao2,3, Wenping Gong4, Yan Li1, Li‐na Niu1, Franklin R. Tay5, Jihua Chen1
1State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Oral Diseases, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, PR China
2Department of Stomatology, the 7th Medical Center of PLA General Hospital, 100700, Beijing, PR China
3Outpatient Department of PLA Macao Garrison, Macao, 999078, PR China
4Army Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Institute of Tuberculosis Research, the 8th Medical Center of PLA General Hospital, 100091, Beijing, PR China
5Department of Endodontics, the Dental College of Georgia, Augusta University, 1120 15th Street, Augusta, GA, 30912, USA

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Calori, 2011, The use of bone-graft substitutes in large bone defects: any specific needs?, Injury, 42, S56, 10.1016/j.injury.2011.06.011

Sui, 2019, Stem cell-based bone regeneration in diseased microenvironments: challenges and solutions, Biomaterials, 196, 18, 10.1016/j.biomaterials.2017.10.046

Roddy, 2018, Treatment of critical-sized bone defects: clinical and tissue engineering perspectives, Eur. J. Orthop. Surg. Traumatol., 28, 351, 10.1007/s00590-017-2063-0

Wang, 2017, Bone grafts and biomaterials substitutes for bone defect repair: a review, Bioact. Mater., 2, 224, 10.1016/j.bioactmat.2017.05.007

Bose, 2012, Recent advances in bone tissue engineering scaffolds, Trends Biotechnol., 30, 546, 10.1016/j.tibtech.2012.07.005

Madl, 2018, Bioengineering strategies to accelerate stem cell therapeutics, Nature, 557, 335, 10.1038/s41586-018-0089-z

Parekkadan, 2010, Mesenchymal stem cells as therapeutics, Annu. Rev. Biomed. Eng., 12, 87, 10.1146/annurev-bioeng-070909-105309

Chen, 2012, Stem cell-delivery therapeutics for periodontal tissue regeneration, Biomaterials, 33, 6320, 10.1016/j.biomaterials.2012.05.048

Daley, 2008, Prospects for stem cell-based therapy, Cell, 132, 544, 10.1016/j.cell.2008.02.009

Murray, 2011, Protective and pathogenic functions of macrophage subsets, Nat. Rev. Immunol., 11, 723, 10.1038/nri3073

Mosser, 2008, Exploring the full spectrum of macrophage activation, Nat. Rev. Immunol., 8, 958, 10.1038/nri2448

Murray, 2014, Macrophage activation and polarization: nomenclature and experimental guidelines, Immunity, 41, 14, 10.1016/j.immuni.2014.06.008

Pajarinen, 2019, Mesenchymal stem cell-macrophage crosstalk and bone healing, Biomaterials, 196, 80, 10.1016/j.biomaterials.2017.12.025

Spiller, 2017, Macrophage-based therapeutic strategies in regenerative medicine, Adv. Drug Deliv. Rev., 122, 74, 10.1016/j.addr.2017.05.010

Das, 2015, Monocyte and macrophage plasticity in tissue repair and regeneration, Am. J. Pathol., 185, 2596, 10.1016/j.ajpath.2015.06.001

Smith, 2017, Harnessing macrophage plasticity for tissue regeneration, Adv. Drug Deliv. Rev., 114, 193, 10.1016/j.addr.2017.04.012

He, 2018, The effects of conditioned media generated by polarized macrophages on the cellular behaviours of bone marrow mesenchymal stem cells, J. Cell. Mol. Med., 22, 1302, 10.1111/jcmm.13431

Vi, 2015, Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis, J. Bone Miner. Res., 30, 1090, 10.1002/jbmr.2422

Champagne, 2002, Macrophage cell lines produce osteoinductive signals that include bone morphogenetic protein-2, Bone, 30, 26, 10.1016/S8756-3282(01)00638-X

Pirraco, 2013, Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs, J. Tissue Eng. Regen. Med., 7, 392, 10.1002/term.535

Chang, 2008, Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo, J. Immunol., 181, 1232, 10.4049/jimmunol.181.2.1232

Nicolaidou, 2012, Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation, PLoS One, 7, 10.1371/journal.pone.0039871

Sun, 2017, Intrafibrillar silicified collagen scaffold modulates monocyte to promote cell homing, angiogenesis and bone regeneration, Biomaterials, 113, 203, 10.1016/j.biomaterials.2016.10.050

Liu, 2018, In vitro cell behaviors of bone mesenchymal stem cells derived from normal and postmenopausal osteoporotic rats, Int. J. Mol. Med., 41, 669

Krause, 1996, CD34: structure, biology, and clinical utility, Blood, 87, 1, 10.1182/blood.V87.1.1.1

Hermiston, 2003, CD45: a critical regulator of signaling thresholds in immune cells, Annu. Rev. Immunol., 21, 107, 10.1146/annurev.immunol.21.120601.140946

Wu, 2018, Biomaterials for endogenous regenerative medicine: coaxing stem cell homing and beyond, Appl. Mater. Today, 11, 144, 10.1016/j.apmt.2018.02.004

Yin, 2017, Influences of age-related changes in mesenchymal stem cells on macrophages during in-vitro culture, Stem Cell Res. Ther., 8, 153, 10.1186/s13287-017-0608-0

Yeler, 2005, Investigation of oxidative stress during fracture healing in the rats, Cell Biochem. Funct., 23, 137, 10.1002/cbf.1199

Schäfer, 2008, Oxidative stress in normal and impaired wound repair, Pharmacol. Res., 58, 165, 10.1016/j.phrs.2008.06.004

Ishii, 2014, Redox status in mammalian cells and stem cells during culture in vitro: critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance, Redox Biol., 2, 786, 10.1016/j.redox.2014.04.008

Bigarella, 2014, Stem cells and the impact of ROS signaling, Development, 141, 4206, 10.1242/dev.107086

Mouthuy, 2016, Biocompatibility of implantable materials: an oxidative stress viewpoint, Biomaterials, 109, 55, 10.1016/j.biomaterials.2016.09.010

Urao, 2013, Redox regulation of stem/progenitor cells and bone marrow niche, Free Radic. Biol. Med., 54, 26, 10.1016/j.freeradbiomed.2012.10.532

Phinney, 2015, Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs, Nat. Commun., 6, 8472, 10.1038/ncomms9472

Jun, 2019, Ceria-incorporated MTA for accelerating odontoblastic differentiation via ROS downregulation, Dent. Mater., 35, 1291, 10.1016/j.dental.2019.05.024

Yamada, 2013, N-acetyl cysteine as an osteogenesis-enhancing molecule for bone regeneration, Biomaterials, 34, 6147, 10.1016/j.biomaterials.2013.04.064

Li, 2019, M2 macrophages enhance the cementoblastic differentiation of periodontal ligament stem cells via the Akt and JNK pathways, Stem Cells, 37, 1567, 10.1002/stem.3076

Goren, 2009, Akt1 controls insulin-driven VEGF biosynthesis from keratinocytes: implications for normal and diabetes-impaired skin repair in mice, J. Invest. Dermatol., 129, 752, 10.1038/jid.2008.230

Zhang, 2016, Exosomes/tricalcium phosphate combination scaffolds can enhance bone regeneration by activating the PI3K/Akt signaling pathway, Stem Cell Res. Ther., 7, 136, 10.1186/s13287-016-0391-3

Wu, 2018, Enhanced osteogenic differentiation and bone regeneration of poly(lactic-: Co -glycolic acid) by graphene via activation of PI3K/Akt/GSK-3β/β-catenin signal circuit, Biomater. Sci., 6, 1147, 10.1039/C8BM00127H

Wu, 2017, Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway, Nat. Commun., 8, 13700, 10.1038/ncomms13700

Xu, 2009, High glucose suppresses epidermal growth factor receptor/ phosphatidylinositol 3-kinase/akt signaling pathway and attenuates corneal epithelial wound healing, Diabetes, 58, 1077, 10.2337/db08-0997

Németh, 2009, Bone marrow stromal cells attenuate sepsis via prostaglandin E 2-dependent reprogramming of host macrophages to increase their interleukin-10 production, Nat. Med., 15, 42, 10.1038/nm.1905

Braza, 2016, Mesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthma, Stem Cells, 34, 1836, 10.1002/stem.2344