Macrophage Cytokines: Involvement in Immunity and Infectious Diseases

Guillermo Arango Duque1,2, Albert Descoteaux1,2
1Centre for Host-Parasite Interactions, Canada
2INRS-Institut Armand-Frappier, Canada

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Tauber, 2003, Metchnikoff and the phagocytosis theory, Nat Rev Mol Cell Biol, 4, 897, 10.1038/nrm1244

Sieweke, 2013, Beyond stem cells: self-renewal of differentiated macrophages, Science, 342, 1242974, 10.1126/science.1242974

Huber, 1981, Macrophages in the regulation of immunity, Haematol Blood Transfus, 27, 31

Unanue, 1976, Regulation of immunity and inflammation by mediators from macrophages, Am J Pathol, 85, 465

Dinarello, 2007, Historical insights into cytokines, Eur J Immunol, 37, S34, 10.1002/eji.200737772

Bernheim, 1976, Fever and antipyresis in the lizard Dipsosaurus dorsalis, Am J Physiol, 231, 198, 10.1152/ajplegacy.1976.231.1.198

Huynh, 2007, Fusion, fission, and secretion during phagocytosis, Physiology (Bethesda), 22, 366, 10.1152/physiol.00028.2007

Biswas, 2010, Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm, Nat Immunol, 11, 889, 10.1038/ni.1937

Stow, 2013, Intracellular trafficking and secretion of inflammatory cytokines, Cytokine Growth Factor Rev, 24, 227, 10.1016/j.cytogfr.2013.04.001

Stow, 2006, SNAREing immunity: the role of SNAREs in the immune system, Nat Rev Immunol, 6, 919, 10.1038/nri1980

Arango Duque, 2013, Synaptotagmin XI regulates phagocytosis and cytokine secretion in macrophages, J Immunol, 190, 1737, 10.4049/jimmunol.1202500

Beutler, 1999, The role of tumor necrosis factor in health and disease, J Rheumatol Suppl, 57, 16

Carswell, 1975, An endotoxin-induced serum factor that causes necrosis of tumors, Proc Natl Acad Sci U S A, 72, 3666, 10.1073/pnas.72.9.3666

Griffin, 2012, IL-17 and TNF-α sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation, J Immunol, 188, 6287, 10.4049/jimmunol.1200385

Vieira, 2009, A crucial role for TNF-α in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5, Br J Pharmacol, 158, 779, 10.1111/j.1476-5381.2009.00367.x

Sozzani, 2014, Chronic inflammatory diseases: do immunological patterns drive the choice of biotechnology drugs? A critical review, Autoimmunity, 47, 287, 10.3109/08916934.2014.897333

Murray, 2005, A role for the phagosome in cytokine secretion, Science, 310, 1492, 10.1126/science.1120225

Pagan, 2003, The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion, Curr Biol, 13, 156, 10.1016/S0960-9822(03)00006-X

Murray, 2005, Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis factor-alpha, J Biol Chem, 280, 10478, 10.1074/jbc.M414420200

Stanley, 2014, The Rho GTPase Rac1 is required for recycling endosome-mediated secretion of TNF in macrophages, Immunol Cell Biol, 92, 275, 10.1038/icb.2013.90

Black, 1997, A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells, Nature, 385, 729, 10.1038/385729a0

Arango Duque, 2014, Leishmania promastigotes induce cytokine secretion in macrophages through the degradation of synaptotagmin XI, J Immunol, 193, 2363, 10.4049/jimmunol.1303043

Baram, 1999, Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells, J Exp Med, 189, 1649, 10.1084/jem.189.10.1649

Czibener, 2006, Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes, J Cell Biol, 174, 997, 10.1083/jcb.200605004

Vinet, 2008, The exocytosis regulator synaptotagmin V controls phagocytosis in macrophages, J Immunol, 181, 5289, 10.4049/jimmunol.181.8.5289

Südhof, 2012, Calcium control of neurotransmitter release, Cold Spring Harb Perspect Biol, 4, a011353, 10.1101/cshperspect.a011353

Wang, 2010, Rat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusion, J Biol Chem, 285, 30759, 10.1074/jbc.M110.137745

Milochau, 2014, Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells, FEBS Lett, 588, 2217, 10.1016/j.febslet.2014.05.031

Ben-Sasson, 2009, IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation, Proc Natl Acad Sci U S A, 106, 7119, 10.1073/pnas.0902745106

Carmi, 2009, The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis, J Immunol, 183, 4705, 10.4049/jimmunol.0901511

Yazdi, 2010, Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta, Proc Natl Acad Sci U S A, 107, 19449, 10.1073/pnas.1008155107

Chen, 2007, Identification of a key pathway required for the sterile inflammatory response triggered by dying cells, Nat Med, 13, 851, 10.1038/nm1603

Ravikumar, 2009, Mammalian macroautophagy at a glance, J Cell Sci, 122, 1707, 10.1242/jcs.031773

Duran, 2010, Unconventional secretion of Acb1 is mediated by autophagosomes, J Cell Biol, 188, 527, 10.1083/jcb.200911154

Dupont, 2011, Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β, EMBO J, 30, 4701, 10.1038/emboj.2011.398

Jiang, 2013, Secretory versus degradative autophagy: unconventional secretion of inflammatory mediators, J Innate Immun, 5, 471, 10.1159/000346707

Brough, 2007, Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death, J Cell Sci, 120, 772, 10.1242/jcs.03377

Marty, 2005, ATP binding cassette transporter ABC1 is required for the release of interleukin-1beta by P2×7-stimulated and lipopolysaccharide-primed mouse Schwann cells, Glia, 49, 511, 10.1002/glia.20138

Qu, 2007, Non-classical IL-1β secretion stimulated by P2×7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages, J Immunol, 179, 1913, 10.4049/jimmunol.179.3.1913

Nishimoto, 2004, Inhibition of IL-6 for the treatment of inflammatory diseases, Curr Opin Pharmacol, 4, 386, 10.1016/j.coph.2004.03.005

Barkhausen, 2011, Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model, Crit Care Med, 39, 1407, 10.1097/CCM.0b013e318211ff56

Hurst, 2001, IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation, Immunity, 14, 705, 10.1016/S1074-7613(01)00151-0

Scheller, 2011, The pro- and anti-inflammatory properties of the cytokine interleukin-6, Biochim Biophys Acta, 1813, 878, 10.1016/j.bbamcr.2011.01.034

Matthews, 2010, Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance, Diabetologia, 53, 2431, 10.1007/s00125-010-1865-y

Manderson, 2007, Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha, J Cell Biol, 178, 57, 10.1083/jcb.200612131

Dorman, 2000, Interferon-γ and interleukin-12 pathway defects and human disease, Cytokine Growth Factor Rev, 11, 321, 10.1016/S1359-6101(00)00010-1

Croxford, 2014, IL-12-and IL-23 in health and disease, Cytokine Growth Factor Rev, 25, 415, 10.1016/j.cytogfr.2014.07.017

Wang, 2000, Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4, Blood, 95, 3183, 10.1182/blood.V95.10.3183

Duitman, 2011, Mechanisms of cytokine secretion: a portfolio of distinct pathways allows flexibility in cytokine activity, Eur J Cell Biol, 90, 476, 10.1016/j.ejcb.2011.01.010

Logan, 2006, A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils, Allergy, 61, 777, 10.1111/j.1398-9995.2006.01089.x

Mollinedo, 2006, Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils, J Immunol, 177, 2831, 10.4049/jimmunol.177.5.2831

Pulecio, 2010, Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse, J Exp Med, 207, 2719, 10.1084/jem.20100007

Gatti, 2002, Effect of interleukin-18 on mouse core body temperature, Am J Physiol Regul Integr Comp Physiol, 282, R702, 10.1152/ajpregu.00393.2001

Lee, 2004, Differences in signaling pathways by IL-1β and IL-18, Proc Natl Acad Sci U S A, 101, 8815, 10.1073/pnas.0402800101

Vanden Eijnden, 2005, IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human, Eur J Immunol, 35, 469, 10.1002/eji.200425677

Yoshida, 2001, WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection, Immunity, 15, 569, 10.1016/S1074-7613(01)00206-0

Stumhofer, 2006, Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system, Nat Immunol, 7, 937, 10.1038/ni1376

Mosser, 2008, Interleukin-10: new perspectives on an old cytokine, Immunol Rev, 226, 205, 10.1111/j.1600-065X.2008.00706.x

Fiorentino, 1991, IL-10 inhibits cytokine production by activated macrophages, J Immunol, 147, 3815, 10.4049/jimmunol.147.11.3815

Chadban, 1998, Interleukin-10 differentially modulates MHC class II expression by mesangial cells and macrophages in vitro and in vivo, Immunology, 94, 72, 10.1046/j.1365-2567.1998.00487.x

Defrance, 1992, Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A, J Exp Med, 175, 671, 10.1084/jem.175.3.671

Rousset, 1992, Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes, Proc Natl Acad Sci U S A, 89, 1890, 10.1073/pnas.89.5.1890

Oswald, 1992, Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation, Proc Natl Acad Sci U S A, 89, 8676, 10.1073/pnas.89.18.8676

Cunha, 1992, Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-gamma in murine macrophages, Biochem Biophys Res Commun, 182, 1155, 10.1016/0006-291X(92)91852-H

Varzaneh, 2014, Cytokines in common variable immunodeficiency as signs of immune dysregulation and potential therapeutic targets – a review of the current knowledge, J Clin Immunol, 34, 524, 10.1007/s10875-014-0053-0

Stanley, 2012, Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages, J Leukoc Biol, 92, 1227, 10.1189/jlb.0412191

Travis, 2014, TGF-β activation and function in immunity, Annu Rev Immunol, 32, 51, 10.1146/annurev-immunol-032713-120257

Becker, 2004, TGF-β suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling, Immunity, 21, 491, 10.1016/j.immuni.2004.07.020

Josefowicz, 2012, Regulatory T cells: mechanisms of differentiation and function, Annu Rev Immunol, 30, 531, 10.1146/annurev.immunol.25.022106.141623

Gleizes, 1997, TGF-β latency: biological significance and mechanisms of activation, Stem Cells, 15, 190, 10.1002/stem.150190

Comerford, 2011, Mini-review series: focus on chemokines, Immunol Cell Biol, 89, 183, 10.1038/icb.2010.164

Moser, 1990, Neutrophil-activating properties of the melanoma growth-stimulatory activity, J Exp Med, 171, 1797, 10.1084/jem.171.5.1797

Pelus, 2006, Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties, Exp Hematol, 34, 1010, 10.1016/j.exphem.2006.04.004

Addison, 2000, The CXC chemokine, monokine induced by interferon-gamma, inhibits non-small cell lung carcinoma tumor growth and metastasis, Hum Gene Ther, 11, 247, 10.1089/10430340050015996

Donlon, 1990, Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12, Genomics, 6, 548, 10.1016/0888-7543(90)90485-D

Maghazachi, 1996, CC chemokines induce the generation of killer cells from CD56+ cells, Eur J Immunol, 26, 315, 10.1002/eji.1830260207

Han, 2009, Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with snare machinery, J Immunol, 182, 2986, 10.4049/jimmunol.0802002

Gouwy, 2004, Synergy between proinflammatory ligands of G protein-coupled receptors in neutrophil activation and migration, J Leukoc Biol, 76, 185, 10.1189/jlb.1003479

Starckx, 2002, Neutrophil gelatinase B and chemokines in leukocytosis and stem cell mobilization, Leuk Lymphoma, 43, 233, 10.1080/10428190290005982

Van Damme, 2004, Chemokine-protease interactions in cancer, Semin Cancer Biol, 14, 201, 10.1016/j.semcancer.2003.10.007

Gijsbers, 2004, CXCR1-binding chemokines in inflammatory bowel diseases: down-regulated IL-8/CXCL8 production by leukocytes in Crohn’s disease and selective GCP-2/CXCL6 expression in inflamed intestinal tissue, Eur J Immunol, 34, 1992, 10.1002/eji.200324807

Rosenblum, 2010, CXC chemokine ligand (CXCL) 9 and CXCL10 are antagonistic costimulation molecules during the priming of alloreactive T cell effectors, J Immunol, 184, 3450, 10.4049/jimmunol.0903831

Keeley, 2008, Chemokines as mediators of neovascularization, Arterioscler Thromb Vasc Biol, 28, 1928, 10.1161/ATVBAHA.108.162925

Dufour, 2002, IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking, J Immunol, 168, 3195, 10.4049/jimmunol.168.7.3195

Cole, 1998, Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3, J Exp Med, 187, 2009, 10.1084/jem.187.12.2009

Gundra, 2014, Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct, Blood, 123, e110, 10.1182/blood-2013-08-520619

Zhang, 2010, Blockade of Notch1 signaling alleviates murine lupus via blunting macrophage activation and M2b polarization, J Immunol, 184, 6465, 10.4049/jimmunol.0904016

Lu, 2013, Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease, Kidney Int, 84, 745, 10.1038/ki.2013.135

Weng, 2007, Alternatively activated macrophages in intestinal helminth infection: effects on concurrent bacterial colitis, J Immunol, 179, 4721, 10.4049/jimmunol.179.7.4721

Hao, 2012, Macrophages in tumor microenvironments and the progression of tumors, Clin Dev Immunol, 2012, 11, 10.1155/2012/948098

Ong, 2012, Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response, Eur J Immunol, 42, 89, 10.1002/eji.201141825

Schoppmann, 2002, Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis, Am J Pathol, 161, 947, 10.1016/S0002-9440(10)64255-1

Sibley, 2011, Invasion and intracellular survival by protozoan parasites, Immunol Rev, 240, 72, 10.1111/j.1600-065X.2010.00990.x

Flannagan, 2009, Antimicrobial mechanisms of phagocytes and bacterial evasion strategies, Nat Rev Microbiol, 7, 355, 10.1038/nrmicro2128

Walsh, 2011, Buruli ulcer: advances in understanding Mycobacterium ulcerans infection, Dermatol Clin, 29, 1, 10.1016/j.det.2010.09.006

George, 2000, Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells, Infect Immun, 68, 877, 10.1128/IAI.68.2.877-883.2000

George, 1999, Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence, Science, 283, 854, 10.1126/science.283.5403.854

Demangel, 2009, Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans, Nat Rev Microbiol, 7, 50, 10.1038/nrmicro2077

Hall, 2014, Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer, Biochem Soc Trans, 42, 177, 10.1042/BST20130133

Simmonds, 2009, Mycolactone inhibits monocyte cytokine production by a posttranscriptional mechanism, J Immunol, 182, 2194, 10.4049/jimmunol.0802294

Torrado, 2007, Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infection, Infect Immun, 75, 3979, 10.1128/IAI.00290-07

Hall, 2014, The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER, PLoS Pathog, 10, e1004061, 10.1371/journal.ppat.1004061

Alvar, 2012, Leishmaniasis worldwide and global estimates of its incidence, PLoS One, 7, e35671, 10.1371/journal.pone.0035671

Kedzierski, 2010, Leishmaniasis vaccine: where are we today?, J Glob Infect Dis, 2, 177, 10.4103/0974-777X.62881

Moradin, 2012, Leishmania promastigotes: building a safe niche within macrophages, Front Cell Infect Microbiol, 2, 121, 10.3389/fcimb.2012.00121

Lodge, 2008, Leishmania invasion and phagosome biogenesis, Subcell Biochem, 47, 174, 10.1007/978-0-387-78267-6_14

Real, 2014, Cell-to-cell transfer of Leishmania amazonensis amastigotes is mediated by immunomodulatory LAMP-rich parasitophorous extrusions, Cell Microbiol, 16, 1549, 10.1111/cmi.12311

Yao, 2010, Major surface protease of trypanosomatids: one size fits all?, Infect Immun, 78, 22, 10.1128/IAI.00776-09

Joshi, 2002, Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor, Mol Biochem Parasitol, 120, 33, 10.1016/S0166-6851(01)00432-7

Matheoud, 2013, Leishmania evades host immunity by inhibiting antigen cross-presentation through direct cleavage of the SNARE VAMP8, Cell Host Microbe, 14, 15, 10.1016/j.chom.2013.06.003

Gómez, 2009, Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases, Sci Signal, 2, ra58, 10.1126/scisignal.2000213

Jaramillo, 2011, Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection, Cell Host Microbe, 9, 331, 10.1016/j.chom.2011.03.008

Hallé, 2009, The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation, J Biol Chem, 284, 6893, 10.1074/jbc.M805861200

Contreras, 2010, Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63, PLoS Pathog, 6, e1001148, 10.1371/journal.ppat.1001148

Ghosh, 2013, Leishmania donovani targets Dicer1 to downregulate miR-122, lower serum cholesterol, and facilitate murine liver infection, Cell Host Microbe, 13, 277, 10.1016/j.chom.2013.02.005

Descoteaux, 2013, Leishmania dices away cholesterol for survival, Cell Host Microbe, 13, 245, 10.1016/j.chom.2013.02.018

Arena, 1997, Production of TNFα and interleukin 6 by differentiated U937 cells infected with Leishmania major, New Microbiol, 20, 233

Matte, 2002, Leishmania-induced cellular recruitment during the early inflammatory response: modulation of proinflammatory mediators, J Infect Dis, 185, 673, 10.1086/339260

Lapara, 2010, Suppression of LPS-induced inflammatory responses in macrophages infected with Leishmania, J Inflamm (Lond), 7, 8, 10.1186/1476-9255-7-8

Wenzel, 2012, Leishmania major parasite stage-dependent host cell invasion and immune evasion, FASEB J, 26, 29, 10.1096/fj.11-184895

Karam, 2006, Leishmania major: low infection dose causes short-lived hyperalgesia and cytokines upregulation in mice, Exp Parasitol, 113, 168, 10.1016/j.exppara.2006.01.003

Jones, 2006, Roles of interleukin-6 in activation of STAT proteins and recruitment of neutrophils during Escherichia coli Pneumonia, J Infect Dis, 193, 360, 10.1086/499312

Biswas, 1998, Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line, Blood, 91, 258, 10.1182/blood.V91.1.258

Belkaid, 2001, The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti–IL-10 receptor antibody for sterile cure, J Exp Med, 194, 1497, 10.1084/jem.194.10.1497

Kane, 2001, The role of IL-10 in promoting disease progression in Leishmaniasis, J Immunol, 166, 1141, 10.4049/jimmunol.166.2.1141

Ribeiro-Gomes, 2014, Site dependent recruitment of inflammatory cells determines the effective dose of Leishmania major, Infect Immun, 82, 2713, 10.1128/IAI.01600-13

Tiwananthagorn, 2012, Involvement of CD4+ Foxp3+ regulatory T cells in persistence of Leishmania donovani in the liver of alymphoplastic aly/aly mice, PLoS Negl Trop Dis, 6, e1798, 10.1371/journal.pntd.0001798

Silva, 2014, CD4+ FOXP3+ cells produce IL-10 in the spleens of dogs with visceral leishmaniasis, Vet Parasitol, 202, 313, 10.1016/j.vetpar.2014.03.010