MYC and PIM2 Co-Expression in Mouse Bone Marrow Cells Readily Establishes Permanent Myeloid Cell Lines That Can Induce Lethal Myeloid Sarcoma In Vivo

Elsevier BV - Tập 34 Số 2 - Trang 201-208 - 2012
Su Hwa Jang1, Hee Yong Chung1
1Department of Biomedical Science, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea

Tóm tắt

Từ khóa


Tài liệu tham khảo

Allen, 1997, Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc, Oncogene, 15, 1133, 10.1038/sj.onc.1201288

Brown, 1997, A PMLRA-Ralpha transgene initiates murine acute promyelocytic leukemia, Proc. Natl. Acad. Sci. USA, 94, 2551, 10.1073/pnas.94.6.2551

Cashman, 1997, Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice, Blood, 89, 4307, 10.1182/blood.V89.12.4307

Chen, 2005, Pim family kinases enhance tumor growth of prostate cancer cells, Mol. Cancer Res, 3, 443, 10.1158/1541-7786.MCR-05-0007

Cheng, 1999, Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha, Proc. Natl. Acad. Sci. USA, 96, 6318, 10.1073/pnas.96.11.6318

Cuenco, 2000, Human AML1/ MDS1/EVI1 fusion protein induces an acute myelogenous leukemia (AML) in mice: a model for human AML, Proc. Natl. Acad. Sci. USA, 97, 1760, 10.1073/pnas.030421197

Deme, 1997, Granulocytic sarcoma of the spine in nonleukemic patients: report of three cases, Neurosurgery, 40, 1283, 10.1097/00006123-199706000-00031

Dick, 1997, Assay of human stem cells by repopulation of NOD/SCID mice, Stem Cells, 15, 199, 10.1002/stem.5530150826

Grisolano, 1994, Early myeloid cellspecific expression of the human cathepsin G gene in transgenic mice, Proc. Natl. Acad. Sci. USA, 91, 8989, 10.1073/pnas.91.19.8989

Grisolano, 1997, Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences, Blood, 89, 376, 10.1182/blood.V89.2.376

Grisolano, 2003, An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice, Proc. Natl. Acad. Sci. USA, 100, 9506, 10.1073/pnas.1531730100

Guzman, 2002, Preferential induction of apoptosis for primary human leukemic stem cells, Proc. Natl. Acad. Sci. USA, 99, 16220, 10.1073/pnas.252462599

Iversen, 2002, Inhibitors of angiogenesis selectively reduce the malignant cell load in rodent models of human myeloid leukemias, Leukemia, 16, 376, 10.1038/sj.leu.2402376

Kroon, 1998, Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b, EMBO J, 17, 3714, 10.1093/emboj/17.13.3714

Lapidot, 1997, Immune-deficient SCID and NOD/SCID mice models as functional assays for studying normal and malignant human hematopoiesis, J. Mol. Med, 75, 664, 10.1007/s001090050150

Lavau, 2000, Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice, Proc. Natl. Acad. Sci. USA, 97, 10984, 10.1073/pnas.190167297

Lawrence, 1999, Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias, Leukemia, 13, 1993, 10.1038/sj.leu.2401578

Luo, 2005, c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations, Blood, 106, 2452, 10.1182/blood-2005-02-0734

Mizuki, 2003, Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations, Blood, 101, 3164, 10.1182/blood-2002-06-1677

Ory, 1996, A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes, Proc. Natl. Acad. Sci. USA, 93, 11400, 10.1073/pnas.93.21.11400

Philpott, 1996, The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques, Blood, 87, 2244, 10.1182/blood.V87.6.2244.bloodjournal8762244

Robbins, 1997, Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells, J. Virol, 71, 9466, 10.1128/jvi.71.12.9466-9474.1997

Schmid, 1994, A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry, J. Immunol. Methods, 170, 145, 10.1016/0022-1759(94)90390-5

Thorsteinsdottir, 1999, The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells, Mol. Cell. Biol, 19, 6355, 10.1128/MCB.19.9.6355

Wang, 2003, SCID-repopulating cell activity of human cord blood-derived CD34-cells assured by intra-bone marrow injection, Blood, 101, 2924, 10.1182/blood-2002-09-2782

Wang, 2010, Pim-2 phosphorylation of p21(Cip1/WAF1) enhances its stability and inhibits cell proliferation in HCT116 cells, Int. J. Biochem. Cell Biol, 42, 1030, 10.1016/j.biocel.2010.03.012

Wierenga, 2003, Differences in heat sensitivity between normal and acute myeloid leukemic stem cells: feasibility of hyperthermic purging of leukemic cells from autologous stem cell grafts, Exp. Hematol, 31, 421, 10.1016/S0301-472X(03)00049-3

Yang, 2011, Pim protein kinase-3 is regulated by TNF-alpha and promotes endothelial cell sprouting, Mol. Cells, 32, 235, 10.1007/s10059-011-1026-z

Yilmaz, 2006, Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells, Nature, 441, 475, 10.1038/nature04703

Yuan, 2001, AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations, Proc. Natl. Acad. Sci. USA, 98, 10398, 10.1073/pnas.171321298

Zhang, 2006, PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention, Nature, 441, 518, 10.1038/nature04747

Zhang, 2008, Pim kinasedependent inhibition of c-Myc degradation, Oncogene, 27, 4809, 10.1038/onc.2008.123