MRI compatible MS2 nanoparticles designed to cross the blood–brain-barrier: providing a path towards tinnitus treatment

Nanomedicine: Nanotechnology, Biology and Medicine - Tập 14 - Trang 1999-2008 - 2018
Aaron K. Apawu1, Stephanie M. Curley2, Angela R. Dixon1, Mirabela Hali1, Moaz Sinan1, Rod D. Braun1, James Castracane2, Anthony T. Cacace3, Magnus Bergkvist2, Avril Genene Holt1,4
1Wayne State University School of Medicine, 540 E Canfield St, Detroit, MI, United States
2SUNY Polytechnic Institute, Colleges of Nanoscale Science and Engineering, 257 Fuller Rd., Albany, NY, United States
3Wayne State University, Department of Communication Sciences & Disorders, 207 Rackham, 60 Farnsworth, Detroit, MI, United States
4John D. Dingell VA Medical Center, 4646 John R St, Detroit, MI, United States

Tài liệu tham khảo

Borlongan, 2013, Epidemiological survey-based formulae to approximate incidence and prevalence of neurological disorders in the United States: a meta-analysis, PLoS One, 8, 10.1371/journal.pone.0078490 Pardridge, 2005, The blood-brain barrier: bottleneck in brain drug development, NeuroRx, 2, 3, 10.1602/neurorx.2.1.3 Hersh, 2016, Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier, Curr Pharm Des, 22, 1177, 10.2174/1381612822666151221150733 Jones, 2007, Blood-brain barrier transport of therapeutics via receptor-mediation, Pharm Res, 24, 1759, 10.1007/s11095-007-9379-0 Herz, 2002, Lipoprotein receptors in the nervous system, Annu Rev Biochem, 71, 405, 10.1146/annurev.biochem.71.110601.135342 Demeule, 2008, Identification and design of peptides as a new drug delivery system for the brain, J Pharmacol Exp Ther, 324, 1064, 10.1124/jpet.107.131318 Demeule, 2008, Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector Angiopep-2, J Neurochem, 106, 1534, 10.1111/j.1471-4159.2008.05492.x Xin, 2011, Angiopep-conjugated poly(ethylene glycol)-co-poly(epsilon-caprolactone) nanoparticles as dual-targeting drug delivery system for brain glioma, Biomaterials, 32, 4293, 10.1016/j.biomaterials.2011.02.044 Bell, 2007, Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system, J Cereb Blood Flow Metab, 27, 909, 10.1038/sj.jcbfm.9600419 Lillis, 2005, Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability, J Thromb Haemost, 3, 1884, 10.1111/j.1538-7836.2005.01371.x Huang, 2011, Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma, Biomaterials, 32, 6832, 10.1016/j.biomaterials.2011.05.064 Xin, 2012, The brain targeting mechanism of Angiopep-conjugated poly(ethylene glycol)-co-poly(epsilon-caprolactone) nanoparticles, Biomaterials, 33, 1673, 10.1016/j.biomaterials.2011.11.018 Xin, 2012, Anti-glioblastoma efficacy and safety of paclitaxel-loading Angiopep-conjugated dual targeting PEG-PCL nanoparticles, Biomaterials, 33, 8167, 10.1016/j.biomaterials.2012.07.046 Ren, 2012, The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2, Biomaterials, 33, 3324, 10.1016/j.biomaterials.2012.01.025 Longmire, 2008, Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats, Nanomedicine (Lond), 3, 703, 10.2217/17435889.3.5.703 Elsabahy, 2012, Design of polymeric nanoparticles for biomedical delivery applications, Chem Soc Rev, 41, 2545, 10.1039/c2cs15327k Yildiz, 2011, Applications of viral nanoparticles in medicine, Curr Opin Biotechnol, 22, 901, 10.1016/j.copbio.2011.04.020 Toropova, 2008, The three-dimensional structure of genomic RNA in bacteriophage MS2: implications for assembly, J Mol Biol, 375, 824, 10.1016/j.jmb.2007.08.067 Kovacs, 2007, Dual-surface-modified bacteriophage MS2 as an ideal scaffold for a viral capsid-based drug delivery system, Bioconjug Chem, 18, 1140, 10.1021/bc070006e Stonehouse, 1993, Effects of amino acid substitution on the thermal stability of MS2 capsids lacking genomic RNA, FEBS Lett, 334, 355, 10.1016/0014-5793(93)80711-3 Valegard, 1990, The three-dimensional structure of the bacterial virus MS2, Nature, 345, 36, 10.1038/345036a0 Holmes, 2011, “Ringing in the ears”: narrative review of tinnitus and its impact, Biol Res Nurs, 13, 97, 10.1177/1099800410382290 Leaver, 2011, Dysregulation of Limbic and Auditory Networks in Tinnitus, Neuron, 69, 33, 10.1016/j.neuron.2010.12.002 Manzoor, 2013, Comparison and contrast of noise-induced hyperactivity in the dorsal cochlear nucleus and inferior colliculus, Hear Res, 295, 114, 10.1016/j.heares.2012.04.003 Cacace, 2014, Manganese enhanced magnetic resonance imaging (MEMRI): a powerful new imaging method to study tinnitus, Hear Res, 311, 49, 10.1016/j.heares.2014.02.003 Holt, 2010, Evidence of key tinnitus-related brain regions documented by a unique combination of manganese-enhanced MRI and acoustic startle reflex testing, PLoS One, 5, 10.1371/journal.pone.0014260 Zhao, 2016, Neural Hyperactivity of the Central Auditory System in Response to Peripheral Damage, Neural Plast, 2016, 10.1155/2016/2162105 Langguth, 2009, Emerging pharmacotherapy of tinnitus, Expert Opin Emerg Drugs, 14, 687, 10.1517/14728210903206975 Bauer, 2016, Clinical trials supported by the Tinnitus Research Consortium: Lessons learned, the Southern Illinois University experience, Hear Res, 334, 65, 10.1016/j.heares.2015.05.001 Anderson, 2006, Viral nanoparticles donning a paramagnetic coat: conjugation of MRI contrast agents to the MS2 capsid, Nano Lett, 6, 1160, 10.1021/nl060378g Stephanopoulos, 2010, Dual-surface modified virus capsids for targeted delivery of photodynamic agents to cancer cells, ACS Nano, 4, 6014, 10.1021/nn1014769 Cohen, 2013, Targeted in vitro photodynamic therapy via aptamer-labeled, porphyrin-loaded virus capsids, J Photochem Photobiol B Biol, 121, 67, 10.1016/j.jphotobiol.2013.02.013 ElSohly, 2015, Synthetically Modified Viral Capsids as Versatile Carriers for Use in Antibody-Based Cell Targeting, Bioconjug Chem, 26, 1590, 10.1021/acs.bioconjchem.5b00226 Brewer, 1967, Evidence for possible nonspecific reactions between N-ethylmaleimide and proteins, Anal Biochem, 18, 248, 10.1016/0003-2697(67)90007-3 Mildvan, 1963, Magnetic resonance studies of the interaction of the manganous ion with bovine serum albumin, Biochemistry, 2, 910, 10.1021/bi00905a003 Anand, 2015, Tailored delivery of analgesic ziconotide across a blood brain barrier model using viral nanocontainers, Sci Rep, 5, 10.1038/srep12497 Manchester, 2006, Virus-based nanoparticles (VNPs): platform technologies for diagnostic imaging, Adv Drug Deliv Rev, 58, 1505, 10.1016/j.addr.2006.09.014 Pitas, 1987, Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins, Biochim Biophys Acta, 917, 148, 10.1016/0005-2760(87)90295-5 Carlos, 2010, Transport Mechanisms at the Blood-Cerebrospinal-Fluid Barrier: Role of Megalin (LRP2), Recent Pat Endocr Metab Immune Drug Discov, 4, 190, 10.2174/1872214811004030190 Meresse, 1989, Low-density lipoprotein receptor on endothelium of brain capillaries, J Neurochem, 53, 340, 10.1111/j.1471-4159.1989.tb07340.x Méresse, 1991, Lipoproteins and Reconstituted Blood-Brain Barrier, 217 Dehouck, 1994, Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes, J Cell Biol, 126, 465, 10.1083/jcb.126.2.465 Dehouck, 1997, A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier, J Cell Biol, 138, 877, 10.1083/jcb.138.4.877 Betzer, 2017, The effect of nanoparticle size on the ability to cross the blood-brain barrier: an in vivo study, Nanomedicine (Lond), 12, 1533, 10.2217/nnm-2017-0022 Shilo, 2015, The effect of nanoparticle size on the probability to cross the blood-brain barrier: an in-vitro endothelial cell model, J Nanobiotechnol, 13, 19, 10.1186/s12951-015-0075-7 Samal, 2014 Chodobski, 2011, Blood-brain barrier pathophysiology in traumatic brain injury, Transl Stroke Res, 2, 492, 10.1007/s12975-011-0125-x Landau, 1955, The local circulation of the living brain; values in the unanesthetized and anesthetized cat, Trans Am Neurol Assoc, 125 Ball, 2007, Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: implications for [(14)C]glucose metabolite trafficking, J Neurosci Res, 85, 3267, 10.1002/jnr.21376 Csiba, 2014, Ultrasound in acute ischemic stroke, 82 Sharan, 2001, A two-phase model for flow of blood in narrow tubes with increased effective viscosity near the wall, Biorheology, 38, 415 Wong, 2013, The blood-brain barrier: an engineering perspective, Front Neuroeng, 6, 7, 10.3389/fneng.2013.00007 Cortes-Sol, 2013, Inner capillary diameter of hypothalamic paraventricular nucleus of female rat increases during lactation, BMC Neurosci, 14, 7, 10.1186/1471-2202-14-7 Karbowski, 2011, Scaling of brain metabolism and blood flow in relation to capillary and neural scaling, PLoS One, 6, 10.1371/journal.pone.0026709 Elmore, 2012, Enhanced histopathology of the immune system: a review and update, Toxicol Pathol, 40, 148, 10.1177/0192623311427571 Hughes, 2005, New insights into the pathology of inherited cardiomyopathy, Heart, 91, 257, 10.1136/hrt.2004.040337 Liu, 2003, Molecular basis of the inflammatory response to adenovirus vectors, Gene Ther, 10, 935, 10.1038/sj.gt.3302036 Frazier, 2013, Urinary system Seely, 2015, Regulatory Forum Opinion Piece*: Dispelling Confusing Pathology Terminology: Recognition and Interpretation of Selected Rodent Renal Tubule Lesions, Toxicol Pathol, 43, 457, 10.1177/0192623315573044