MIR-23A microRNA cluster inhibits B-cell development

McKercher, 1996, Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities, EMBO J, 15, 5647, 10.1002/j.1460-2075.1996.tb00949.x Pevny, 1995, Development of hematopoietic cells lacking transcription factor GATA-1, Development, 121, 163, 10.1242/dev.121.1.163 Scott, 1994, Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages, Science, 265, 1573, 10.1126/science.8079170 Zhang, 1997, Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice, Proc Natl Acad Sci U S A, 94, 569, 10.1073/pnas.94.2.569 Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5 Biryukova, 2009, Drosophila mir-9a regulates wing development via fine-tuning expression of the LIM only factor, dLMO, Dev Biol, 327, 487, 10.1016/j.ydbio.2008.12.036 Schratt, 2009, Fine-tuning neural gene expression with microRNAs, Curr Opin Neurobiol, 19, 213, 10.1016/j.conb.2009.05.015 Dahl, 2003, The importance of PU.1 concentration in hematopoietic lineage commitment and maturation, Blood Cells Mol Dis, 31, 229, 10.1016/S1079-9796(03)00152-9 Dahl, 2003, Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor, Nat Immunol, 4, 1029, 10.1038/ni973 Flynt, 2008, Biological principles of microRNA-mediated regulation: shared themes amid diversity, Nat Rev Genet, 9, 831, 10.1038/nrg2455 Emambokus, 2003, Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb, EMBO J, 22, 4478, 10.1093/emboj/cdg434 Xiao, 2007, MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb, Cell, 131, 146, 10.1016/j.cell.2007.07.021 Lu, 2008, MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors, Dev Cell, 14, 843, 10.1016/j.devcel.2008.03.012 Fazi, 2005, A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis, Cell, 123, 819, 10.1016/j.cell.2005.09.023 Fontana, 2007, MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation, Nat Cell Biol, 9, 775, 10.1038/ncb1613 Velu, 2009, Gfi1 regulates miR-21 and miR-196b to control myelopoiesis, Blood, 113, 4720, 10.1182/blood-2008-11-190215 DeKoter, 2000, Regulation of B lymphocyte and macrophage development by graded expression of PU.1, Science, 288, 1439, 10.1126/science.288.5470.1439 Walsh, 2002, Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates, Immunity, 17, 665, 10.1016/S1074-7613(02)00452-1 Horman, 2009, Gfi1 integrates progenitor versus granulocytic transcriptional programming, Blood, 113, 5466, 10.1182/blood-2008-09-179747 Laslo, 2006, Multilineage transcriptional priming and determination of alternate hematopoietic cell fates, Cell, 126, 755, 10.1016/j.cell.2006.06.052 Weigelt, 2009, Transcriptomic profiling identifies a PU.1 regulatory network in macrophages, Biochem Biophys Res Commun, 380, 308, 10.1016/j.bbrc.2009.01.067 Fujita, 2008, miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism, J Mol Biol, 378, 492, 10.1016/j.jmb.2008.03.015 Fukao, 2007, An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling, Cell, 129, 617, 10.1016/j.cell.2007.02.048 Landgraf, 2007, A mammalian microRNA expression atlas based on small RNA library sequencing, Cell, 129, 1401, 10.1016/j.cell.2007.04.040 Cho, 1999, Functional characterization of B lymphocytes generated in vitro from embryonic stem cells, Proc Natl Acad Sci U S A, 96, 9797, 10.1073/pnas.96.17.9797 Allman, 2003, Thymopoiesis independent of common lymphoid progenitors, Nat Immunol, 4, 168, 10.1038/ni878 De Marchis, 2009, A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells, Leukemia, 23, 656, 10.1038/leu.2008.372 Rosa, 2007, The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation, Proc Natl Acad Sci U S A, 104, 19849, 10.1073/pnas.0706963104 Wang, 2008, MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4, Blood, 111, 588, 10.1182/blood-2007-05-092718 Ben-Ami, 2009, A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis, Proc Natl Acad Sci U S A, 106, 238, 10.1073/pnas.0811466106 Feng, 2009, MicroRNA-27 enhances differentiation of myeloblasts into granulocytes by post-transcriptionally downregulating Runx1, Br J Haematol, 145, 412, 10.1111/j.1365-2141.2009.07632.x Mishra, 2007, A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance, Proc Natl Acad Sci U S A, 104, 13513, 10.1073/pnas.0706217104 Lal, 2008, p16(INK4a) translation suppressed by miR-24, PLoS ONE, 3, e1864, 10.1371/journal.pone.0001864 Lal, 2009, miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells, Nat Struct Mol Biol, 16, 492, 10.1038/nsmb.1589 Walker, 2009, microRNA-24a is required to repress apoptosis in the developing neural retina, Genes Dev, 23, 1046, 10.1101/gad.1777709 Lal, 2009, miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3'UTR microRNA recognition elements, Mol Cell, 35, 610, 10.1016/j.molcel.2009.08.020 Zaidi, 2009, Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network, Cancer Res, 69, 8249, 10.1158/0008-5472.CAN-09-1567 Takagi, 2010, MicroRNAs regulate human hepatocyte nuclear factor 4alpha, modulating the expression of metabolic enzymes and cell cycle, J Biol Chem, 285, 4415, 10.1074/jbc.M109.085431 Chan, 2010, Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression, EMBO J, 29, 559, 10.1038/emboj.2009.370 Wu, 2010, Induction of anion exchanger-1 translation and its opposite roles in the carcinogenesis of gastric cancer cells and differentiation of K562 cells, Oncogene, 29, 1987, 10.1038/onc.2009.481 Celeste, 2002, Genomic instability in mice lacking histone H2AX, Science, 296, 922, 10.1126/science.1069398 Habib, 2007, Myc stimulates B lymphocyte differentiation and amplifies calcium signaling, J Cell Biol, 179, 717, 10.1083/jcb.200704173 Morrow, 1992, Interleukin-7 induces N-myc and c-myc expression in normal precursor B lymphocytes, Genes Dev, 6, 61, 10.1101/gad.6.1.61 He, 2008, c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo, Development, 135, 2467, 10.1242/dev.020131