MEG3 Activated by Vitamin D Inhibits Colorectal Cancer Cells Proliferation and Migration via Regulating Clusterin

EBioMedicine - Tập 30 - Trang 148-157 - 2018
Yan Zhu1, Peizhan Chen2, Yisha Gao1, Na Ta1, Yunshuo Zhang1, Jialin Cai2, Yong Zhao3, Shupeng Liu4, Jianming Zheng1
1Department of Pathology, Changhai Hospital, Secondary Military Medical University, Shanghai 200433, PR China
2Translational Medicine Research Center, Ruijin Hospital North, Shanghai Jiao Tong University School of Medicine, Shanghai 201821, PR China
3Office of Shanghai Administrative Committee for Laboratory Animal, Shanghai, Laboratory Animals Research Center, Shanghai, 201203, PR China
4Clinical Research Center, Changhai Hospital, Secondary Military Medical University, Shanghai 200433, PR China

Tài liệu tham khảo

Aggarwal, 2016, Cross talk between the calcium-sensing receptor and the vitamin D system in prevention of cancer, Front. Physiol., 7, 451, 10.3389/fphys.2016.00451 Arnold, 2017, Global patterns and trends in colorectal cancer incidence and mortality, Gut, 66, 683, 10.1136/gutjnl-2015-310912 Bando, 1999, Loss of heterozygosity of 14q32 in colorectal carcinoma, Cancer Genet. Cytogenet., 111, 161, 10.1016/S0165-4608(98)00242-8 Cai, 2017, Prognostic biomarker identification through integrating the gene signatures of hepatocellular carcinoma properties, EBioMedicine, 19, 18, 10.1016/j.ebiom.2017.04.014 Chen, 2003, Clusterin as a biomarker in murine and human intestinal neoplasia, Proc. Natl. Acad. Sci. U. S. A., 100, 9530, 10.1073/pnas.1233633100 Deng, 2013, The loss of miR-26a-mediated post-transcriptional regulation of cyclin E2 in pancreatic cancer cell proliferation and decreased patient survival, PLoS One, e76450, 8 Duffy, 2017, Vitamin D analogues: potential use in cancer treatment, Crit. Rev. Oncol. Hematol., 112, 190, 10.1016/j.critrevonc.2017.02.015 Elimrani, 2017, Vitamin D reduces colitis- and inflammation-associated colorectal Cancer in mice independent of NOD2, Nutr. Cancer, 69, 276, 10.1080/01635581.2017.1263346 Guinney, 2015, The consensus molecular subtypes of colorectal cancer, Nat. Med., 21, 1350, 10.1038/nm.3967 Jiang, 2014, LncRNA profiling reveals new mechanism for VDR protection against skin cancer formation, J. Steroid Biochem. Mol. Biol., 144, 87 Jiang, 2014, LncRNA: a new player in 1alpha, 25(OH)(2) vitamin D(3)/VDR protection against skin cancer formation, Exp. Dermatol., 23, 147, 10.1111/exd.12341 Kong, 2016, Long non-coding RNAs: novel prognostic biomarkers for liver metastases in patients with early stage colorectal cancer, Oncotarget, 7, 50428, 10.18632/oncotarget.10416 Lee, 2016, eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells, Oncotarget, 7, 18541, 10.18632/oncotarget.8105 Li, 2014, Review: the impacts of circulating 25-hydroxyvitamin D levels on cancer patient outcomes: a systematic review and meta-analysis, J. Clin. Endocrinol. Metab., 99, 2327, 10.1210/jc.2013-4320 Li, 2016, Clusterin induced by N,N′-Dinitrosopiperazine is involved in nasopharyngeal carcinoma metastasis, Oncotarget, 7, 5548, 10.18632/oncotarget.6750 Li, 2017, MEG3 is a prognostic factor for CRC and promotes chemosensitivity by enhancing oxaliplatin-induced cell apoptosis, Oncol. Rep., 38, 1383, 10.3892/or.2017.5828 Li, 2018, LncRNA MEG3 inhibits cell proliferation and metastasis in chronic myeloid leukemia via targeting MiR-184, Oncol. Res., 26, 297, 10.3727/096504017X14980882803151 Lin, 2015, Comparison of survival and clinicopathologic features in colorectal cancer among African American, Caucasian, and Chinese patients treated in the United States: results from the surveillance epidemiology and end results (SEER) database, Oncotarget, 6, 33935, 10.18632/oncotarget.5223 Lu, 2013, Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression, BMC Cancer, 13, 461, 10.1186/1471-2407-13-461 Luo, 2017, Long non-coding RNAs: a rising biotarget in colorectal cancer, Oncotarget, 8, 22187, 10.18632/oncotarget.14728 Ma, 2016, Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/beta-catenin signalling pathway via suppression of activator protein 2alpha, Gut, 65, 1494, 10.1136/gutjnl-2014-308392 Marchese, 2017, The multidimensional mechanisms of long noncoding RNA function, Genome Biol., 18, 206, 10.1186/s13059-017-1348-2 Menigatti, 2013, Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions, Oncogene, 2 Modali, 2015, Epigenetic regulation of the lncRNA MEG3 and its target c-MET in pancreatic neuroendocrine tumors, Mol. Endocrinol., 29, 224, 10.1210/me.2014-1304 Mondal, 2015, MEG3 long noncoding RNA regulates the TGF-beta pathway genes through formation of RNA-DNA triplex structures, Nat. Commun., 6, 7743, 10.1038/ncomms8743 Morales-oyarvide, 2016, Vitamin D and physical activity in patients with colorectal Cancer: epidemiological evidence and therapeutic implications, Cancer J., 22, 223, 10.1097/PPO.0000000000000197 Ohtsuka, 2016, H19 noncoding RNA, an independent prognostic factor, regulates essential Rb-E2F and CDK8-beta-catenin signaling in colorectal Cancer, EBioMedicine, 13, 113, 10.1016/j.ebiom.2016.10.026 Pan, 2015, Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis, Br. J. Cancer, 113, 763, 10.1038/bjc.2015.260 Ponting, 2009, Evolution and functions of long noncoding RNAs, Cell, 136, 629, 10.1016/j.cell.2009.02.006 Radziwon-Balicka, 2014, Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway, Carcinogenesis, 35, 324, 10.1093/carcin/bgt332 Ramagopalan, 2010, A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution, Genome Res., 20, 1352, 10.1101/gr.107920.110 Su, 2016, Skp2 regulates non-small cell lung cancer cell growth by Meg3 and miR-3163, Tumour Biol., 37, 3925, 10.1007/s13277-015-4151-2 Torre, 2015, Global cancer statistics, 2012, CA Cancer J. Clin., 65, 87, 10.3322/caac.21262 Walsh, 2003, Colorectal cancer screening: scientific review, JAMA, 289, 1288, 10.1001/jama.289.10.1288 Wang, 2012, Clusterin confers resistance to TNF-alpha-induced apoptosis in breast cancer cells through NF-kappaB activation and Bcl-2 overexpression, J. Chemother., 24, 348, 10.1179/1973947812Y.0000000049 Wang, 2015, Clusterin facilitates metastasis by EIF3I/Akt/MMP13 signaling in hepatocellular carcinoma, Oncotarget, 6, 2903, 10.18632/oncotarget.3093 Wu, 2015, LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression, Oncotarget, 6, 32890, 10.18632/oncotarget.5335 Yan, 2009, Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis, EMBO J., 28, 2719, 10.1038/emboj.2009.214 Yin, 2015, Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer, Tumour Biol., 36, 4851, 10.1007/s13277-015-3139-2 Yu, 2015, Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer, Gut, 64, 636, 10.1136/gutjnl-2013-306620 Yuan, 2017, The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1, Nat. Cell Biol., 19, 820, 10.1038/ncb3538 Zhang, 2003, A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells, J. Clin. Endocrinol. Metab., 88, 5119, 10.1210/jc.2003-030222 Zhang, 2017, LncRNA MEG3 inhibits cell epithelial-mesenchymal transition by sponging miR-421 targeting E-cadherin in breast cancer, Biomed Pharmacother, 91, 312, 10.1016/j.biopha.2017.04.085 Zhao, 2006, Cyclic AMP stimulates MEG3 gene expression in cells through a cAMP-response element (CRE) in the MEG3 proximal promoter region, Int. J. Biochem. Cell Biol., 38, 1808, 10.1016/j.biocel.2006.05.004 Zhou, 2012, MEG3 noncoding RNA: a tumor suppressor, J. Mol. Endocrinol., 48, R45, 10.1530/JME-12-0008 Zhu, 2013, Function of lncRNAs and approaches to lncRNA-protein interactions, Sci. China Life Sci., 56, 876, 10.1007/s11427-013-4553-6 Zwain, 2001, cAMP-induced apoptosis in granulosa cells is associated with up-regulation of P53 and bax and down-regulation of clusterin, Endocr. Res., 27, 233, 10.1081/ERC-100107184