MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer

Beheshti Zavareh, 2012, Suppression of cancer progression by MGAT1 shRNA knockdown, PLoS One, 7, 10.1371/journal.pone.0043721 Bello, 2010, Novel 2‑[(benzylamino)methyl]pyrrolidine‑3,4‑diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies, Bioorg. Med. Chem., 18, 3320, 10.1016/j.bmc.2010.03.009 Bhat, 2017, Shifted Golgi targeting of glycosyltransferases and alpha-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells, Biochim. Biophys. Acta, 1861, 2891, 10.1016/j.bbagen.2017.08.006 Borgwardt, 2014, Alpha-mannosidosis - a review of genetic, clinical findings and options of treatment, Pediatr. Endocrinol. Rev., 12, 185 Cao, 2017, p-Akt as a potential poor prognostic factor for gastric cancer: a systematic review and meta-analysis, Oncotarget, 8, 59878, 10.18632/oncotarget.17001 Chen, 2017, Cancer incidence and mortality in China, 2013, Cancer Lett., 401, 63, 10.1016/j.canlet.2017.04.024 Chen, 2017, MAN2A1-FER fusion gene is expressed by human liver and other tumor types and has oncogenic activity in mice, Gastroenterology, 153, 1120, 10.1053/j.gastro.2016.12.036 Duarte, 2017, 18 Duronio, 2008, The life of a cell: apoptosis regulation by the PI3K/PKB pathway, Biochem. J., 415, 333, 10.1042/BJ20081056 Ferlay, 2015, Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012, Int. J. Cancer, 136, E359, 10.1002/ijc.29210 Gajate, 2017, Prognostic and predictive role of the PI3K-AKT-mTOR pathway in neuroendocrine neoplasms, Clin. Transl. Oncol., 20, 561, 10.1007/s12094-017-1758-3 Hou, 2015, Protective macroautophagy is involved in vitamin E succinate effects on human gastric carcinoma cell line SGC-7901 by inhibiting mTOR axis phosphorylation, PLoS One, 10, 10.1371/journal.pone.0132829 Jayaprakash, 2017, Role of glycosylation in nucleating protein folding and stability, Biochem. J., 474, 2333, 10.1042/BCJ20170111 Jennewein, 2017, The immunoregulatory roles of antibody glycosylation, Trends Immunol., 38, 358, 10.1016/j.it.2017.02.004 Korkolopoulou, 2012, A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma, BJU Int., 110, E1237, 10.1111/j.1464-410X.2012.11569.x Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) method, Methods, 25, 402, 10.1006/meth.2001.1262 Mahdavifar, 2016, Epidemiology, incidence and mortality of bladder cancer and their relationship with the development index in the world, Asian Pac. J. Cancer Prev., 17, 381, 10.7314/APJCP.2016.17.1.381 Malm, 1993, Alpha-mannosidosis Nguyen, 2017, Organelle specific O-glycosylation drives MMP14 activation, tumor growth, and metastasis, Cancer Cell, 32, 639, 10.1016/j.ccell.2017.10.001 Oliveira-Ferrer, 2017, Role of protein glycosylation in cancer metastasis, Semin. Cancer Biol., 44, 141, 10.1016/j.semcancer.2017.03.002 Olszewska, 2012, Possible role of alpha-mannosidase and beta-galactosidase in larynx cancer, Contemp. Oncol., 16, 154 Shi, 2017, Cell recognition molecule L1 regulates cell surface glycosylation to modulate cell survival and migration, Int. J. Med. Sci., 14, 1276, 10.7150/ijms.20479 Tian, 2008, Inhibition of α‑mannosidase Man2c1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis, Cancer Sci., 99, 2428, 10.1111/j.1349-7006.2008.01019.x Torre, 2015, Global cancer statistics, 2012, CA Cancer J. Clin., 65, 87, 10.3322/caac.21262 Vajaria, 2017, Glycosylation: a hallmark of cancer?, Glycoconj. J., 34, 147, 10.1007/s10719-016-9755-2 Varki, 2015, Glycosylation changes in cancer Veillon, 2017 Yoshida, 2017 Zhang, 2013, Resveratrol inhibits human nasopharyngeal carcinoma cell growth via blocking pAkt/p70S6K signaling pathways, Int. J. Mol. Med., 31, 621, 10.3892/ijmm.2013.1237