MALT Lymphoma of Caecum Presenting as Acute Intestinal Obstruction: A Case Report
Tóm tắt
Mucosa-associated lymphoid tissue lymphomas (MALT lymphoma) are well known, but colonic MALT lymphomas are extremely rare. We report the first case of mucosa-associated lymphoid tissue (MALT) lymphoma in the cecum from India presenting as acute intestinal obstruction with mass in right iliac fossa showing diffuse thickening of ascending colon and caecum with obliterated lumen along with nodular mass on CECT scan of abdomen. On video colonoscopy, circumferential ulcerated growth was seen at cecum, and the rest of the colon was normal. Multiple biopsies from growth suggested malignancy. Right hemicolectomy was performed. The histopathology of resected specimen demonstrated low-grade B-cell MALT lymphoma of the cecum, and the depth of invasion was up to the muscular layer. This was confirmed by immunohistochemistry.
Tài liệu tham khảo
Issacson PG, Wright DH (1983) Malignant lymphoma of mucosa-associated lymphoid tissue: a distinctive type of B-cell lymphoma. Cancer 52:1410–1416
Stanojevic GZ, Nestorovic MD, Brankovic BR, Stojanovic MP, Jovanovic MM, Radojkovic MD (2011) Primary colorectal lymphoma: an overview. World J Gastrointest Oncol 15:14–18
Bacon CM, Du MQ, Ahmet D (2007) Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists. J Clin Pathol 60:361–372
Miyazaki T, Ishiguro T, Ishibashi K, Itoyama S, Ishida H (2010) Mucosa-associated lymphoid tissue lymphoma of the appendix vermiformis. Int Surg 95:27–32
Ahlawat S, Kanber Y, Charabaty-Pishvaian A, Ozdemirli M, Cohen P, Benjamin S et al (2006) Primary mucosa-associated lymphoid tissue (MALT) lymphoma occurring in the rectum: a case report and review of the literature. South Med J 99:1378–1384
Ghulam MA, Khush MS, Anwarul H, Mukhtar HR (2001) Maltoma: a rare diagnosis in common presentation. Biomedica 17:1–2
Neubauer A, Christian T, Birgit A, Markus R, Beatrix N, Gerhard E (1997) Cure of Helicobacter pylori infection and duration of remission of low-grade gastric mucosa-associated lymphoid tissue lymphoma. J Natl Cancer Inst 89:1350–1355
Raderer M, Pfeffel F, Pohl G, Mannhalter C, Valencak J, Chott A (2000) Regression of colonic low grade B cell lymphoma of the mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Gut 46:133–135
Nakase H, Okazaki K, Ohana M, Ikeda K, Uchida K, Uose S et al (2002) The possible involvement of microorganisms other than Helicobacter pylori in the development of rectal MALT lymphoma in H. pylori-negative patients. Endoscopy 34:343–346